preLights

A preprint highlights service run by the biological community and supported by The Company of Biologists

[preLights @preLights]

🚨 Call for preLighters!🚨

Help us highlight the most exciting biological preprints. Share your insights, build your profile, and be part of a supportive community! 🌍

Interested? Apply today & help shape the future of science publishing! 📢

More info: https://t.co/SJeh69HFGU

[preLights @preLights]

Gut feeling about ageing: intestinal ceramidase Asah2 as a conserved regulator of vertebrate lifespan.

Jeny Jose highlights a #preprint that addresses the fascinating question: What controls the rate at which we age? ⌛

Read the #preLight to learn more: https://t.co/8p8j54ypez

[preLights @preLights]

1 species, 13 phyla, one simple geometric rule that appears to set when every embryo starts speaking through its own genome.🧬

Panagiotis Giannios highlights a recent #preprint from @mirimiam & collaborators #EvolutionaryBiology

Check out the #preLight: https://t.co/ZIJJWjLsYS

[preLights @preLights]

But corals aren’t alone in facing multiple stressors

A #preprint by @khuongaquatic & team explores how a tropical coastal copepod balances warming + pollution (copper) - with knock-on effects for feeding & reproduction 🦐

#preLight by Tina Nguyen👉 https://t.co/vmjReoaJBR

[preLights @preLights]

As marine heatwaves intensify, who survives - and why?

Maitri Manjunath highlights recent work from Zoe Meziere & colleagues who studied the variation in coral thermal stress responses during a real-time marine heatwave 🪸 #preprint #ecology

#preLight: https://t.co/rZQIjIA0k5

[Ali H. Shaib @AliHShaib]

Hello world, meet 1,000× Expansion Microscopy.
1,000,000,000× expansion by volume! A gel that starts at a few centimeters will then expand to the volume of an Olympic swimming pool. https://t.co/E43kxx4O5M
In our new bioRxiv preprint, work carried out between MIT and UMG, led by Helena Hu in collaboration with scientists from the labs of @eboyden3 Ed Boyden, Silvio Rizzoli, and myself, we present Thousandfold Expansion Microscopy.
By enlarging biological specimens across multiple rounds of expansion, molecular-scale features, as small as the distances between adjacent amino acids, can be visualized with conventional optical microscopes.
Democratizing super-resolution microscopy.

[Sudha Kumari @Sudha__Kumari]

What if we could control actin polymerization in living systems—precisely in time and scale, on demand?

We attempt it in our latest preprint :
https://t.co/BHef8ebl3o

[preLights @preLights]

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

This study from the labs of Maria José Sá and Carles Ubeda highlights how complex diseases like MS require multidisciplinary approaches.

https://t.co/4IJhKBamUD

[preLights @preLights]

ASCL1 can’t always make neurons alone…

In this 2‑minute #Short, Jethro @lundie_brown explains how chromatin priming and co‑factors shape cell fate decisions in embryonic stem cells. #StemCells #DevBio

https://t.co/elaFmCpXZV

[the Node @the_Node]

preLighters’ choice – A curated selection of recent preprints

In this post on the Node, read concise #preprint highlights of recent #DevBio and #StemCell biology papers prepared by the @preLights community.

https://t.co/p8luR3MKGS

[preLights @preLights]

Aquatic adventures in heart regeneration❤️

Study from the @simoesfili Lab looks at zebrafish hearts after cryoinjury to identify ligand-receptor circuits and macrophage states that facilitate #regeneration. #preprint

#preLight by Theodora Stougiannou ⬇️
https://t.co/zKeopNwnOY

[preLights @preLights]

Pairing acute SUZ12 degradation + simplified embryoids, Ming-Kang Lee and team pinpoint time-dependent sensitivities to PRC2 loss. #preprint #MeissnerLab

Check out the latest #preLight prepared by María Mariner-Faulí 👀⬇️
https://t.co/OWSxVNbHcr

[preLights @preLights]

Friction at the tip keeps the Drosophila germ band straight against innate instabilities. #DevBio

Ruoheng Li (@LiRuoheng36210) highlights a #preprint from @GiuliaSerafin12 and colleagues @PavelTomancak Lab

#preLight + an insightful author response 👀⬇️
https://t.co/I3sYTSiCax

[preLights @preLights]

The challenge of in vitro gametogenesis. #DevBio

Alan Leung highlights a #preprint from the Hamer’s Lab that identifies the specific metabolites and proteins in immature hPGCLSc that could create a maturation bottleneck.

#preLight + an author response ⬇️
https://t.co/isev4w9HEv

[FocalPlane @focalplane_jcs]

Last chance to submit your images for our FocalPlane-ELMI2026 @EuLiMI1 image competition!

[Journal of Experimental Biology @J_Exp_Biol]

To support new junior faculty, JEB launched Kickstart Travel Grants to establish a new collaboration & and ECR Visiting Fellowships to bring an ECR to their new lab for a defined project. The next application deadline is 5 June
https://t.co/A4r7eRBGBj

[The Company of Biologists @Co_Biologists]

Science is a story – join the communities that tell it. Every experiment has a backstory. Every figure, failure and breakthrough is shaped by people, choices and chance. Science is rich with narratives waiting to be uncovered.

[DMM Journal @DMM_Journal]

Head to @prelights website and read a preprint about changes in gut microbiome over the course of multiple sclerosis, chosen by Carole Djagang, Nour HAROUN, Phalica Georges and uMontreal Neuro preLighters.

Prelight: https://t.co/eNsunIALUA
Preprint: https://t.co/KkJuUfDY2V

[preLights @preLights]

Sun2: the great separator of healthy tissue repair and pathological fibrosis?

Emma Carley, Sandra Sandria & colleagues show that Sun2 is a key modulator of the fibroblast response #preprint

Beth Chopak highlights their work and speaks to Sandra Sandria⬇️
https://t.co/OpDrZZrFnT

[Andrew Savinov @bioSavinov]

Interested in genetically encodable inhibitors of your favorite biomolecular condensate? Excited to announce our latest work, w/ @jibin_sadasivan, @GeneWeiLiLab, & @LindsayCase19, on protein fragments as generalizable regulators of phase separation. (1/n)
https://t.co/6IMkrTP3ZQ

[preLights @preLights]

What’s new in #DevBio? 👀

Our preLighters Theodora, @sandaklyj, @NathSristilekha & @DeevithaB have handpicked a selection of exciting #preprints in this area.

Check out the #preList and let us know your favourite, recent DevBio preprint ⬇️:
https://t.co/DGhvqhDXlt