Minimum Effective Dose

The MED Report filters the noise so you don't have to. Evidence-based health intelligence for people who want maximum healthspan with minimum effort.

[Minimum Effective Dose @TheMEDReport]

I've spent thousands of hours reading books, digging through studies, and following protocols — all chasing the same thing.

A clear answer. A reliable path. Something that actually works.

Every time I found it — the next expert debunked it.

Sound familiar? 🧵👇

[Minimum Effective Dose @TheMEDReport]

A normal LDL does not automatically mean low cardiovascular risk.

ApoB, Lp(a), blood pressure, glucose, kidney function and plaque can change the picture.

✅ Verdict: SIGNAL. Measure the risk, not just LDL.

https://t.co/PN7M5PYL1A

[Minimum Effective Dose @TheMEDReport]

Want the bigger healthspan picture?

I put the interventions I would prioritize first into the free MED Report Healthspan Stack.

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[Minimum Effective Dose @TheMEDReport]

Are you actually low risk for heart attack and stroke?

A normal-looking cholesterol panel does not prove it.

Part 1 of our 4-part cardiovascular series: what to measure before deciding what to change.

Thread 🧵

[Minimum Effective Dose @TheMEDReport]

My minimum-effective risk stack:

Core: BP, standard lipids, glucose/A1c, kidney function, waist/BMI, smoking + family history
Baseline: ApoB + Lp(a)
Conditional: hsCRP, UACR, CAC
Skip routine particle-size and exotic panels

https://t.co/i4gXWlGkfV

[Minimum Effective Dose @TheMEDReport]

A normal LDL does not automatically mean low heart attack risk.

ApoB, Lp(a), blood pressure, glucose, kidney function and plaque can change the picture.

Tomorrow: Part 1 of our 4-part cardiovascular series.

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[Minimum Effective Dose @TheMEDReport]

My oil rule is simple:
Use EVOO or avocado oil by default.
Choose high-oleic oils when you want neutral flavor.
Fresh conventional seed oils are not poison.
Avoid rancid or repeatedly heated oil.

Full breakdown https://t.co/i4gXWlGkfV

[Minimum Effective Dose @TheMEDReport]

Same seed. Different oil.

Regular sunflower is rich in easily oxidized linoleic acid.

High-oleic sunflower contains much more stable monounsaturated fat and holds up better under heat.

That is why “seed oil” is too crude a category.

Full breakdown at https://t.co/i4gXWlGkfV

[Minimum Effective Dose @TheMEDReport]

A reassuring review on seed oils was funded by ILSI North America. Its lead author disclosed consulting for Monsanto and Bunge.
That does not make the data false.
But when funding change how reassuring the evidence looks, disclosure matters. Full breakdown https://t.co/i4gXWlGkfV

[Minimum Effective Dose @TheMEDReport]

Seed oils are the wrong category.

Fresh seed oil and repeatedly heated seed oil are not the same exposure. The useful question is oxidation, processing, storage and heat.

Verdict: oxidized and degraded oils are ☠️ Harmful.

https://t.co/CmC3TknEfG

[Minimum Effective Dose @TheMEDReport]

Want the bigger healthspan picture?

I put the interventions I would prioritize first into the free MED Report Healthspan Stack.

Get it here:
https://t.co/i4gXWlGkfV

[Minimum Effective Dose @TheMEDReport]

Seed oils are toxic. Seed oils are healthy. Who is right?

Both sides use one label for very different exposures.

Fresh oil, chips stored for months, and oil held hot in a fryer all day are not the same thing.

Thread 🧵

[Minimum Effective Dose @TheMEDReport]

My practical hierarchy:

✅ Default: EVOO + avocado
✅ Neutral option: high-oleic oils
🟢 Ghee/tallow: useful for heat if LDL/ApoB support it
⚠️ Fresh conventional seed oils: acceptable, not preferred
☠️ Avoid degraded/reused oil

https://t.co/i4gXWlGkfV