Hydroalkylation of Vinylarenes by Transition-Metal-Free In Situ Generation of Benzylic Nucleophiles Using Tetramethyldisiloxane and Potassium tert-Butoxide (Stephen G. Newman and co-workers) @TheNewmanLab#openaccess 🔓 https://t.co/q93YsFdmQD
@TheNewmanLab had a fun time @qomsboc 2024. Thanks @diaogroupNYU for her valuable feedback and a shout out to @arefvaezghaemi for winning best oral presentation @ Piers for best poster. Celebrations continued thereafter. Big thanks to @RousseauxGroup for being a great organizer!
Common reactants, uncommon outcome. See how @czc_chem achieved atypical regioselectivity in the Mizoroki-Heck reaction of vinyl boronates in @JOC_OL
https://t.co/txCZ95YbQd
A huge effort led by recent PhD graduate Adam Cook, who just received a prestigious Banting Postdoctoral Fellowship. Good luck in the Wender group @StanfordUChem
Ni-catalyzed deoxygenative arylation of alcohols via an SN1-type mechanism thanks to the β-silicon effect and new wide bite angle NHC ligands. Now online in @JACS.
https://t.co/WzjRS2pumx
Congrats @ Adam for a wonderful PhD defence followed by an awesome after party with the entire @TheNewmanLab. It was a great privilege working alongside you for the last two years!!!!
Mizoroki-Heck reactions with cyclic enones are surprisingly difficult. Read our latest work in collaboration with @Pfizer in @ACSCatalysis to find out why.
https://t.co/CZoN13OHUu
@ChemRxiv Our review is now online @ACSChemRev (https://t.co/LnXyIbWGEn). Take a look to see some creative ways chemists have come up with to directly use alcohols in transition metal catalysis.
How can we better use feedstock molecules and avoid stoichiometric functional group interconversion steps? PhD student Adam Cook documents how catalysis can enable complexity-building reactions with alcohols, now on @ChemRxiv (https://t.co/EE51FyjMn2)
@awhspeed@JACS@RowleyGroup@jmblacquiere Thanks Alex. Like most things, the 'rules of thumb' here are not quite as universal or as rigorously constructed as we tend to think. It's quite a challenge to figure out exactly which Heck reactions work with high yield/selectivity and which ones don't.
Exceptional control of regioselectivity in the Mizoroki-Heck reaction enabled by P2N2 ligands now online @JACS. Great collaboration with @RowleyGroup, @jmblacquiere, and recent PhD graduate Eric Isbrandt . https://t.co/uofflNtd1b
Synthesis of Secondary Benzylic Alcohols by Reductive Arylation of Aldehydes: α-Phenyl-6-quinolinemethanol
Gilian T. Thomas, Eric S. Isbrandt, and Stephen G. Newman
https://t.co/vXkACQuktl
@TheNewmanLab from the @uOttawaCHM presents a Ni/Bi dual-catalyzed method for the Suzuki–Miyaura arylation of tertiary alcohols. Find out more about his research 👉 https://t.co/MHo1mqv3nX
The Keith Fagnou Award is presented to a scientist residing in Canada who has made a distinguished contribution to organic chemistry while working in Canada. Congrats to Dr. Stephen Newman @TheNewmanLab of @UOttawa on being the recipient of this award. https://t.co/SPpsznw8O8