Christoph Rau

Assistant Professor of Computational Medicine at UNC-Chapel Hill. Interested in good discussions and collaborations!
Other: @christophrau.bsky.social

[Christoph Rau @The_DataDragon]

@The_New_Roman @CharlieIceman2 @WallStreetApes Right, depending on age range. For infants (the cost we have up there) its 3 kids per adult. I suspect that for 4 year olds the cost is maybe half that.

[Christoph Rau @The_DataDragon]

@Zhero00 @CharlieIceman2 @WallStreetApes For infants, the ratio is mandated at 1:3, toddlers is 1:4, and preschool is 1:10 which is why costs get cheaper the older your kids are. Factor in floating teachers to cover breaks, janitors, rent, health insurance, liability insurance... cost checks out... and is also so high!

[Christoph Rau @The_DataDragon]

@CrawfordCu86299 @JeffJacksonNC https://t.co/5ez49QGzbF

You are welcome.

[Christoph Rau @The_DataDragon]

@LaurieM65533565 @lindawiliams @JeffJacksonNC Of course, it is published and has been published for decades now if you just care to look. Here you are: https://t.co/5ez49QGzbF

[Christoph Rau @The_DataDragon]

.@washingtonpost You cowards. Good riddance.

[Christoph Rau @The_DataDragon]

@cmclymer It’s less what and more how. OP is right that on, say, a video game podcast, many of the ads are for right wing podcasts who advertise themselves as reasonable but are not. I’ve NEVER heard a single ad from the left on one of them, so of course the pull is in one direction.

[Re-energising Your Career @career_re]

#AcademicTwitter Yes!😂#phdlife #phdvoice

[Michaela Patterson @caelagamoo]

Check out our latest from the Patterson Lab - a method to assess cardiomyocyte division along with many other useful metrics all from the same heart: https://t.co/TwdUTwxmLw

Hoping the bench top protocol is not far behind! @ScientistSwift

[oso-tee.bsky.social | Oluwatobi (Tobi) Oso☄️ @OSO_Tee]

My PI: So, do you have a plan?

Me: I have concepts of a plan

My PI:

[Tom Vondriska @VondriskaLab]

📢Looking for postdoc to study biomechanics of chromatin & role of histones as stress sensors @UCLA. Other projects #Cardiovascular #Epigenetics, #HFpEF, #Circadian biology. Email Tom Vondriska for details…Please RT!
#postdoc #academicchatter @dgsomucla
https://t.co/EeNHQiSykR

[Christoph Rau @The_DataDragon]

Imagine this one as being a cool GIF. Not sure why its not animating :|

[Christoph Rau @The_DataDragon]

Myocardial infarctions change both cell-specific expression and cell-type abundance. Can we algorithmically disentangle these two signals in bulk RNAseq data?

Yes!

Excited to share the first paper from the Rau lab, led by @BrianGural!
https://t.co/GQqx9u2SLB

[Christoph Rau @The_DataDragon]

He then showed that the initial enriched GO terms in the DGE b/t WT MI and KO MI mice, largely genes associated with fibroblast abundance (which was old news!) lost significance while novel genes involved in fundamental heart integrity were highlighted as crucially important!

[Christoph Rau @The_DataDragon]

Thanks again to @BrianGural who led this project, along with all our collaborators in the Brian Jensen, Tom Vondriska, Michaela Patterson, and Caitlin O'Meara labs.
https://t.co/GQqx9u3qB9

[Christoph Rau @The_DataDragon]

We have a lot more happening with this approach, with exciting results to share shortly about what happens when you apply this algorithm to-scale across 100s of RNAseq datasets. We want to understand the noise that cell-type composition adds to our analyses!