Thorsten Langner

Independent Research Group Leader at the Max Planck Institute for Biology, Tuebingen. Adaptive evolution of filamentous plant pathogens.

[Thorsten Langner @ThorstenLangner]

@KamounLab @ATinyGreenCell @GetGenome @nanopore This move seems to go directly against the consumers, especially in labs where the sequencer doesnt run 24/7 (or where basecalling is done on a cluster).

[Thorsten Langner @ThorstenLangner]

@KamounLab @ATinyGreenCell @GetGenome The worst decision by @nanopore is to discontinue the P2 solo (to push the P2 integrated)! Currently we can use the external computer (with powerful GPU) for other applications (e.g. modelling) while not sequencing (i.e. basecalling). Now nanopore is taking this flexibility away.

[Sophien Kamoun @KamounLab]

Hugely honored to attend Professor Ryohei Terauchi's @ryoheiterauchi lecture at Kyoto University @KyotoU_News.

What a spectacular career exploring crop evolution and molecular plant pathology / immunity. And a lasting impact on many Early Career Scientists.

[Nick Desnoyer @NickDesnoyer]

Why I’m genetically engineering a rainbow flower…

And how a Russian fairy tale inspired the idea 🧵

[Mauricio Contreras @mpcontreras4]

Check out our new story on the famous rice Pik NLR pair, led by @ClemMarchal and @HsuanPai1 ! Turns out they form a massive 1 MDa membrane-associated complex before activation 🤯 A cool new example of the diversity of NLR resting states!

[Hsuan Pai 白暄 @HsuanPai1]

The Pik NLR pair does more than just wait for activation!
Adding to the known modes of action for NLR proteins: from monomer/dimer to a novel pre-activation heterocomplex 🤜🤛
Get the full mechanism in our new preprint!

[Takema Fukatsu @fkttkm]

Our long-lasting research project on an amazing stinkbug-fungus relationship "Defensive fungal symbiosis on insect hindlegs" finally comes out in Science! https://t.co/J3y9mLJHuR #symbiosis #insect #fungus #stinkbug

[Lida Derevnina @lderevnina]

🔬 PhD opportunity alert! Join us at the @CropSciCentre @camplantsci to decode sensor–helper NLR communication mechanisms in plant immunity. Apply by 14th November! 🔍 More info 👉 https://t.co/RwM3TMiWaR #PhD #PlantScience #Biology Please RT

[Chih-Hang Wu @AdamWu9527]

Please RT! Exciting opportunities in plant–microbe interactions!
My lab @IPMBSinica is looking for passionate postdocs & RAs to join us in one of the following areas:
✨ Cell death & immune signaling
🧬 Discovery of resistance genes
🧫 Development of Agrobacterium-based tools

[Sophien Kamoun @KamounLab]

First a pentamer, then a hexamer… now an octamer!

The riddle of the enigmatic CCG10-NLR immune receptor family cracked open 🔥

Congrats Guanghao @GuanghaoGuo He Zhang @mhz1989 Selva @M__Selvaraj et al.

#NLRbiology #plantsci #immunology

[M. Selvaraj @M__Selvaraj]

Please read here about a plant disease resistance protein that makes an octameric resistosome. We describe about its identification, architecture, action and assembly.
Congrats to all involved. @GuanghaoGuo, He Zhao @mhz1989
@jonathandgjones @KamounLab @TheSainsburyLab 👇

[Fantin Mesny @f_mesny]

📣 NEW PREPRINT 📝

We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.

cc @Team_Thomma

https://t.co/aeyB8xWnRC

[Sophien Kamoun @KamounLab]

Fave study and paper… #EvolutionRocks #EVOMPMI #EffectorWisdom 👇🏾

[Thorsten Langner @ThorstenLangner]

Where is this type of work heading? We propose an experimental framework for predicting and testing of evolutionary outcomes of pathogen effector—host target interactions. This has implications for preparing for the next disease outbreak and plant disease resistance breeding.

[Thorsten Langner @ThorstenLangner]

We’re excited to share our latest work on plant pathogen effector protein evolution @biorxivpreprint. With @KamounLab and Abbas Maqbool.
https://t.co/qAEgS6hOes

[Thorsten Langner @ThorstenLangner]

Two of these homoplasic amino acids are located in the binding interface to host HMA proteins! Interestingly, previous functional studies already suggested an adaptive role of these sites.
https://t.co/LSdmUD3MIm
https://t.co/iu8K8ts7BQ

[Thorsten Langner @ThorstenLangner]

Two of these homoplasic amino acids are located in the binding interface to host HMA proteins! Interestingly, previous functional studies already suggested an adaptive role of these sites.
https://t.co/LSdmUD4kxU
https://t.co/iu8K8tsFro