Timothy Cleland

Vertebrate Paleontologist • Mass Spectrometrist • Physical Scientist at Smithsonian (tweets are my own)

[asher newsome @the_ion_doctor]

My newest publication is now out in #IJMS. Dopants have been used to tweak microflow ESI before, but this is for 300 nL/min emitters and nanoLCMS. This is another application of my in-line permeation device 2021 pub. w/ @TimClelandPaleo
(open access link) https://t.co/lJkT1Pba2g

[Timothy Cleland @TimClelandPaleo]

We found a broad proteome with patterns similar to human milk. This project will be a baseline for future milk projects on more individuals of these species.

[Timothy Cleland @TimClelandPaleo]

Michael Power at the National Zoo invited me to collaborate on exploring the milk proteome from gorilla and orangutan across lactation https://t.co/bn6Bo2Y9IA

[Timothy Cleland @TimClelandPaleo]

@DrPardi There have been some recent papers using FT-IR to evaluate protein preservation for organic stable isotopes, and something similar may apply to radiocarbon

[Timothy Cleland @TimClelandPaleo]

The next director position for @SmithsonianMCI is open for anyone qualified including international researchers. https://t.co/zOiTNYMsRl

[Timothy Cleland @TimClelandPaleo]

@neely615 I currently have several projects with them. There are quite a few researchers at the National Zoo who are interested in proteomics so they keep me busy.

[asher newsome @the_ion_doctor]

Come to poster 266 to see my charge manipulation for nano-sprayed proteins! #ASMS2022

[Timothy Cleland @TimClelandPaleo]

@GarciaLabMS

[Timothy Cleland @TimClelandPaleo]

@GarciaLabMS @asmsnews

[Timothy Cleland @TimClelandPaleo]

@GarciaLabMS

[Timothy Cleland @TimClelandPaleo]

@neely615 @the_ion_doctor I learned that as a kid, but they didn’t have 2 brains. It is an expansion of the spinal cord in the sacral region.

[Timothy Cleland @TimClelandPaleo]

@NorSivaeb I’ve had quite a few reviews where the authors found only a few collagen peptides because they didn’t search for HYP and after review found hundreds. It really doesn’t make sense to exclude it on ECM studies.

[Timothy Cleland @TimClelandPaleo]

@neely615 I found a similar result on a serum project, but I wasn’t able to find any lit supporting this when I started the project. I ended up doing a short internal report to my collaborators that depletion wasn’t the way to go for the project.

[Timothy Cleland @TimClelandPaleo]

Mary Schweitzer, @ERSchroeter, and I have a new perspective in @JProteomeRes on deep time paleoproteomics https://t.co/qkhT82wwN2

[Frido Welker @FridoWelker]

Finally, Cleland (@TimClelandPaleo) and colleagues propose "diagenetiforms" as a term to facilitate proper discourse on diagenetic PTM landscapes of ancient proteins. https://t.co/0O21HDhYRI

[Timothy Cleland @TimClelandPaleo]

We give a short retrospective on the dinosaur peptides, the current state of deep time paleoproteomics (enamel and eggshell), and future directions we see for paleoproteomics. We also give some extensional areas that paleoproteomics could be applied to.

[Timothy Cleland @TimClelandPaleo]

Mary Schweitzer, @ERSchroeter, and I have a new perspective in @JProteomeRes on deep time paleoproteomics https://t.co/qkhT82wwN2

[Timothy Cleland @TimClelandPaleo]

@TomHoltzPaleo Preserved proteins and 1 Ma DNA

[Timothy Cleland @TimClelandPaleo]

@HazelR_D This was one of the example test files from the company. I thought about making a Triceratops one though

[Timothy Cleland @TimClelandPaleo]

When you are a paleontologist and get a new liquid handling robot, you make a Stegosaurus.

[Timothy Cleland @TimClelandPaleo]

@DRAWheatcraft OT-2