Armin Toghi

Cognitive neuroscience -Interested in Predictive processing//neuroimaging/TMS

[Armin Toghi @ToghiArmin]

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

https://t.co/QoxDphIXEK

[Adeel Razi @adeelrazi]

We are hiring for our psilocybin clinical trial.

1. Research Officer (testing and screening), 2 positions
https://t.co/HMQ6wXqGiM

2. Research Officer (Peer Navigator)

https://t.co/q80dVBeHMW

DM if you have questions.
@WellcomeLeap @VerdejoGAntonio @DrSuziNielsen @dpsyc42

[Adeel Razi @adeelrazi]

Very excited about our new DishBrain paper, see Moein’s thread below.

We show that in vitro neurons have higher sampling efficiency compared to the state of the art deep reinforcement learning.

Paper: https://t.co/uStgt9PRgl

[Armin Toghi @ToghiArmin]

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

https://t.co/QoxDphIXEK

[Armin Toghi @ToghiArmin]

Any comments would be useful for improving the work!!

feel free to criticize 🙂

[Armin Toghi @ToghiArmin]

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

https://t.co/QoxDphIXEK

[Armin Toghi @ToghiArmin]

Using a multilevel parametric empirical Bayes framework, we observed that
1. cTBS induce wider network effect 2 min after stimulation while iTBS made more lasting changes up to 30 min.
2. TBS caused sustained inhibition within left sgACC microcircuits by increased ss inhibition

[Armin Toghi @ToghiArmin]

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

https://t.co/QoxDphIXEK

[Aaron Boes @boeslab]

Does TMS delivered to the dlPFC elicit a response in the subgenual ACC?

New work with intracranial EEG says yes!
@NickTrapp13 @DrCoreyKeller @jingjiang_psy

Preprint here:
https://t.co/6fnYWLNk36

[Armin Toghi @ToghiArmin]

@yael_niv Starter packs make things easy there

[NIMH_RDoC @NIMH_RDoC]

Spotlight on the Cognitive Systems Domain! An insightful paper examining the potential integration of the Predictive Processing framework and the #RDoC framework when studying #psychopathology; https://t.co/KnBpxDM2at @ToghiArmin @CPSYJournal

[Armin Toghi @ToghiArmin]

@TaraRezapour @VCU @EkhtiariHamed Congrats 🎉

[Armin Toghi @ToghiArmin]

Although the current evidence does not fully support its utility in validating, in cases where PP encompasses both interpretable physiological components (MMN as PE) and known underlying circuitry, it demonstrates a strong capability for connecting different units of analysis.

[Armin Toghi @ToghiArmin]

Excited to share our new paper, published on @CPSYJournal

https://t.co/GYUpPUV6xW

This review tries to address possible contributions of the Predictive Processing Framework to the @NIMH_RDoC matrix.

Key insights [1]:

[Armin Toghi @ToghiArmin]

Next, we turned to PP’s explanatory potential in integrating different units of analysis, to bring a mechanistic understanding of connections between biomarkers and clinical traits by targeting particular RDoC construct (Perception).

[Armin Toghi @ToghiArmin]

These results could have potential clinical implications, given the known associations between exploration-exploitation imbalances and psychopathologies.

[Armin Toghi @ToghiArmin]

Happy to share that our work is now published in @SciReports

https://t.co/QupbRXjPbm

Our study explored the causal role of right DLPFC in different explorative strategies, using TMS and Horizon task.

[Armin Toghi @ToghiArmin]

Key findings:
cTBS over rDLPFC vs Vertex

1.Decision noise only in total uncertainty condition ([2 2]) reduced in both horizons: random exploration reduced by increasing general reward sensitivity

2.Information bonus and spatial bias parameters intact in both horizons