Trevor

Founder @CaravelBio building new protein machines | MO➡️MA➡️OR

[Trevor @TrevorBNicks]

100% - Systems that enable measurement and thus informed-design to be done quickly will be very valuable.

[Clive G. Brown @The__Taybor]

I’ve come to the view that AI in biology will actually boost measurement, e.g. sequencing. AI in biology means more constructs, more edits, more synthetic genomes, more single cells, more hypothetical proteins to express and characterize, more validation, more perturbation of cells, best measured by deep sequencing of transcripts/proteins etc.

[Polly Fordyce @fordycelab]

For the computational community, this is the part we're most excited about 👇

APB-Display's fast turnaround (< 1 week) and low cost (<15¢/variant) could make it possible to actually close active learning loops on protein-binding models. (9/n)

[Trevor @TrevorBNicks]

This is like that meme where people keep saying their dog’s favorite words, but for my scientific interests

[Olivier Borkowski @O_Borkowski]

Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates
https://t.co/qwUUAzzCtd

[Gaurab Chakrabarti @Gaurab]

Sumitomo Chemical declared force majeure yesterday, making it the fifth Asian chemical company in a single week. First Chandra Asri in Indonesia, then Yeochun NCC in South Korea. By March 5, Petrochemical Corporation of Singapore had declared force majeure on 1.1 million tons of ethylene capacity on Jurong Island. Aster followed a day later with its cracker running at half capacity. The root cause is the same for all five: naphtha, the feedstock these plants break down into the base chemicals behind plastics, rubber, and packaging. Asian steam crackers source most of their naphtha from the Middle East, and virtually all of it transits the Strait of Hormuz. When the Strait closed, all five lost their feedstock within days. Five force majeures in seven days. This is a massive disruption of the chemicals that hold the global economy together. Polymer prices are already up double digits. Everything downstream gets more expensive from here.

[Trevor @TrevorBNicks]

@nimivashi15 @GustoHQ We are leaving them after a similar experience. So terrible

[Trevor @TrevorBNicks]

@manishtanks It has been a crazy week

[Tom Ellis @ProfTomEllis]

Biolab robots have been a big topic on here this week. Not everyone $2m+ to spend, but plenty of labs have an OpenTrons and we're happy to now share a standard Golden Gate Cloning Workflow for their latest models, that we call "SLOWPOKE"
https://t.co/8DJxkCYmdP

[charlota @0xCharlota]

"everyone will just vibecode all the apps they need now!" has that "everyone will just print everything they need on their 3D printer now!" energy

[bioRxiv Synthetic Biology @bioRxiv_synbio]

PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized non-ribosomal proteins https://t.co/6lnXiRKumc #biorxiv_synbio

[Trevor @TrevorBNicks]

@SynBio1 This is some of your best work

[Alex Iskold | 2048.vc @alexiskold]

Pre-Seed should not take months and months to raise!

We are thrilled to announce that @2048vc is launching Pre-Seed Fast Track to help you get funding in 10 business days.

If you are raising $500K - $1.5M Pre-Seed round in Vertical AI, Deep Tech, Health or Bio we would love to meet you!

We offer clear and transparent process and money in the bank within 10 business days of the first meeting.

To start the process submit your pitch through our short form - https://t.co/SqAoEbTMLl

If there is a potential fit we will reach out within a few days and follow these steps to fund you:

Step 1: Intro meeting via Zoom: 30 mins where you meet with 1 member of our team.

Step 2: Deep Dive via Zoom: 60 mins where you meet with 3-4 members of our team.

Step 3: References + In-Person Meeting: We will chat with your early customers and professional references, and will spend a few hours to get to know each other in person. Startups are long journeys and we know how important the investor-founder fit is, so we will gladly pay for your travel.

Step 4: Term sheet: We make you an offer from $250K - $750K

Step 5: Wire: We are high conviction and don’t wait for the rest of the round to come together - we wire as soon as we sign the docs.

To learn more about Pre-Seed Fast Track visit https://t.co/kCgKU8ZZ12.

We can’t wait to review your pitches and to meet you!

@2048vc // #preseed

[Trevor @TrevorBNicks]

Hey, Boston folks! @2048vc wrote the first check in @CaravelBio. Their diligence process was both the fastest and most thorough I’ve experienced - which gave us confidence we were picking the right investors and can give you confidence they’ll be great co-workers.

[Zann @thisiszann]

We’re hiring an Associate for the @2048vc team in Boston! 🚀

We lead a dozen+ pre-seed and seed rounds each year across Vertical AI, Deep Tech, Health, and Bio.

We love being the first YES & we're incredibly privileged to work with founders at the earliest moments in their journeys.

Boston has become one of the most exciting places to do that: world-class schools, labs, and a growing community of ambitious founders. So we’re doubling down.

This is a rare hire for us.

You’ll be on the ground with me sourcing, meeting founders, supporting on deals, and helping to build a preeminent pre/seed fund.

The sweet spot: 2–5 years of experience, prior venture/early-stage investing exposure, and a strong network. Ideally already in Boston or happy to relocate.

Please help me spread the word! Link and application below

[Neel Joshi @jeloshine]

Check out our new paper on using whole bacteria and protein nanofibers to make biodegradable bioplastics with tunable properties. @M_B_Avinash did an amazing job conceiving and developing this idea.
https://t.co/Qh7UjCKKsz

[Trevor @TrevorBNicks]

This, but importantly it’s my dog’s costume.

[Michael Benjamin @mfbenji]

Gay guys love a Halloween costume that requires a 2 minute backstory and reference photo

[Trevor @TrevorBNicks]

@nimivashi15 Thank you!

[Trevor @TrevorBNicks]

I made a spicy BLT so good that I cried a little

[Heather Lindsy @_heatherlindsy]

St Louis won the water lily weigh off at @mobotgarden with 142 lbs!!! We did it! Thanks @denverbotanic for challenging other botanical gardens to partake!

[Jake Becraft @DrSynbio]

I firmly believe science fiction writers are the closest thing we have to science “philosophers” or “futurists.” And the few I know spend more time thinking about the likely deep future than almost any research scientist I know.