Tylerlindell

Founder & GP, ASDF | Autoimmune & Inflammatory Disease Biotech Fund | living w/ T1D

[Tylerlindell @Tylerlindell]

https://t.co/bBIPXEjLf3

[Tylerlindell @Tylerlindell]

@grok @UGSPECIAL @ElonMuskAOC Someone's got tell him

[Tylerlindell @Tylerlindell]

When an investor says

"interesting, but we want to see more progress"

they're not asking for speed

They're waiting for permission

Most founders think progress creates permission

It doesn't

That's why they keep building

and the answer never shows up

[Tylerlindell @Tylerlindell]

@parmita capital ignores biotech for years

then binge-funds it like it's just discovered oxygen

Fire? What fire?

[Tylerlindell @Tylerlindell]

@_simonsmith ChatGPT treating PubMed like the dark web.

[Tylerlindell @Tylerlindell]

@mark_k @OpenAI ChatGPT treating PubMed like the dark web

[Tylerlindell @Tylerlindell]

@_simonsmith chatGPT: "Interesting… but have you considered jail?"

[Tylerlindell @Tylerlindell]

@louisanicola_ ibuprofen after lifting = slower growth.

Inflammation is the adaptation trigger;

blunt it, blunt gains.

Let it clear up on it's own or push harder the next day.

[Tylerlindell @Tylerlindell]

@MilanPosts @lucabianchin7 Inflammation -> pubalgia is real

One bad move ends a season

Milan chose well

[Tylerlindell @Tylerlindell]

@OrganicLiveFood If honey + cinnamon beat cancer, Big Pharma would be bankrupt by now 🤣 Use it daily, just don’t skip the doctor.

[Tylerlindell @Tylerlindell]

Most meaningful work starts the same way:

- no playbook
- unclear ownership
- high stakes

I stepped into it at rLoop/SpaceX (Hyperloop pod) and later at Tesla (cross-org AR/VR initiative). Progress came from listening hard, creating clarity, and helping people move when certainty was gone.

That's what draws me now: working with autoimmune biotech founders in unknown territory who value judgment, signal, and the next right move (over the loud one).

If you're building something hard + early + real and want a sharper lens on what you're proving next:

DMs open for a second set of eyes on your plan.

[Tylerlindell @Tylerlindell]

It's more expensive to be unclear than to be wrong

[Tylerlindell @Tylerlindell]

There's a pause -
You feel it through the screen

Because the science is weak? No.
It's because the plan doesn't hold under load yet

And in that moment,
you can't open 12 tabs

Pre-seed biotech decks rarely fail on science
They fail because this answer isn't obvious

[Tylerlindell @Tylerlindell]

It's early, before the day really starts
Too many tabs open
A founder’s deck I've already read three times
My notes from the founder call
An FDA guidance doc I keep reopening

I reread the same slide again
It sounds fine

[Tylerlindell @Tylerlindell]

A Plan Page is one page that removes ambiguity:
- what gets proven next,
- how it gets tested,
- and what outcome actually matters

Because this question doesn't disappear
It shows up later on a Zoom with an investor:
"Ok... what are you proving next?"

[Tylerlindell @Tylerlindell]

Don't be afraid of confusion

Confusion is not a dead end

It is the starting line

It means you're about to trade a comfortable lie for an uncomfortable truth.

- R. Feynman

[Tylerlindell @Tylerlindell]

Complexity grows exponentially

[Tylerlindell @Tylerlindell]

Motion is comforting
Movement is confrontational

[Tylerlindell @Tylerlindell]

Your job as a founder is to apply force until reality changes state.