Miren como Peña Nieto celebro aquel gol de Rafa Márquez vs Croacia en el Mundial de Brasil 2014, ese día se olvido que era el Presidente de la Nación y fue un aficionado mas apoyando a México🇲🇽❤️🔥
COMO SE EXTRAÑA A PEÑA NIETO 🥹🇲🇽
🍻Informa #Monterrey que se permitirá beber alcohol en vía pública sólamente en el "Corredor FIFA" que comienza desde plaza Zaragoza, Barrio Antiguo, Santa Lucía hasta fundidora. Las bebidas deben estar en vasos de plástico y podrá consumirse hasta las 6:00am
¡SIMPLEMENTE ESPECTACULAR! 😍
Así luce el Andador 20 de Noviembre en Zapopan de cara a la Copa del Mundo ❤️
Bordados con los siete países que jugarán la justa en Guadalajara 🇲🇽 🇰🇷 🇨🇿 🇨🇴 🇨🇩 🇪🇸 🇺🇾
#JustoAhora Así vivieron en la zona hotelera de #Cancún el sismo de esta tarde. Hoteles evacuaron como medida precautoria.
Hasta el último reporte de las autoridades, no hay daños. Información en desarrollo
📌 Impact of Radionecrosis and Local Recurrence on Overall Survival After Stereotactic Radiosurgery for Brain Metastases 🧠
🔗 https://t.co/zLFWzoaKKY
@ASTRO_org@EJVaios@PeterFecci@MuzamilArshad18
🔹1383 pts
🔸 large, multi-institutional cohort
🔹 Patients diagnosed with LR were diagnosed sooner after SRS than RN (5.8 vs 8.3 months)
🔸 Local recurrence was associated with significantly worse OS than radionecrosis (15.2 vs 40.4 months)
🔹 Patients symptomatic from either LR or RN presented earlier after SRS than asymptomatic patients and had worse OS
🔸 On binomial logistic regression, RN was associated with single fraction SRS (odds ratio [OR] = 0.38, P = 0.012), receipt of immunotherapy after SRS (OR = 0.32, P < 0.014), and a longer interval from SRS (OR = 0.94, P = 0.028).
Can 3 Gy help osteoarthritis pain?
In this US retrospective series, LDRT 0.5 Gy x 6 improved mean Numeric Rating Scale pain scores from 7.3 to 2.6 at ~12 weeks, with 79% achieving a clinically meaningful ≥2-point reduction.
Low burden.
Noninvasive.
Interesting signal for selected patients with persistent OA pain.
#OncTwitter #RadOnc
🚨Hungry for a new α/β study?🚨
🧪📉 We often quote α/β ratios in clinic as if they’re fixed truths — but where do those numbers actually come from?
This study compared in vitro vs. clinical α/β estimates across prostate, breast, and head & neck cancers and...
... they often do NOT match.
Key findings:
📍Prostate: in vitro α/β ~3.8 Gy vs clinical ~2.3 Gy
🦀Breast: fairly similar (~3.6-3.9 Gy)
🗣️H&N: clinical estimates actually HIGHER than lab estimates (~14 vs 9 Gy)
Why it matters for everyday radonc 👇
⚠️ The “standard” α/β assumptions we use for BED/EQD2 calculations, hypofractionation discussions, and protocol design may oversimplify real tumors.
🧬 Tumor heterogeneity, hypoxia, stem-cell populations, ADT, and the tumor microenvironment likely make clinical tumors behave very differently from cell lines grown in a dish.
💡 Practical takeaway:
When we debate fractionation schedules or compare regimens, remember that the radiobiology behind those BED calculations is probably messier than the spreadsheet suggests.
The paper also reinforces that the classic “10 Gy for most tumors” assumption likely doesn’t hold true for many disease sites. 📚
https://t.co/5JOWRK6G6d
@ASTRO_org