Vytaute Boreikaite

Postdoc with @plaschka_lab at @IMPvienna
PhD student with @lapassmore at @MRC_LMB
Previously @Cambridge_Uni (@QueensCam & @JesusCollegeCam)

Not active on X

[Manuel Carminati @_M_Carminati]

Our work on Pol II dephosphorylation and its connection to transcription regulation and mRNA 3' end processing by the Cleavage and Polyadenylation Factor (CPF) is now out in @MolecularCell!

[Plaschka Lab @plaschka_lab]

Human mRNAs form globules in 3D and are prepared for export by the transcription-export complex. We are excited to share this and more mechanistic insights in our newest work, co-lead by the fantastic @bpachecofiallos and @MVorlandr. https://t.co/3gek1QRSu2 (1/9)

[Lori Passmore @lapassmore]

Fun times in the Passmore lab!
Congratulations to @VBoreikaite who has just completed her PhD!

[Lori Passmore @lapassmore]

New work from @_M_Carminati shows that dephosphorylation of RNA polymerase II by CPF (the 3' end processing machinery) promotes Pol II dimerisation. @mcemremnv @MRC_LMB @ERC_Research

[Lori Passmore @lapassmore]

Work from @rodriguezmol on the role of Mpe1 in mRNA 3' end processing is now out in @MolecularCell !
This was a team effort including @FJ_OReilly @FagarasanHolly @EleanorSheekey @RappsilberLab @ERC_Research @MRC_LMB

[IMBA imbavienna.bsky.social @IMBA_Vienna]

And concluding #Microsymposium2022 with the #PhDworkshop prizes!

1st prize goes to @lisababalisa from @juliusbrennecke's lab at IMBA!

The two 2nd prizes go to @VBoreikaite (@MRC_LMB) and @MakiGoesScience from our neighboring @gmivienna !

Congratulations to the awardees!

[IMBA imbavienna.bsky.social @IMBA_Vienna]

#Microsymposium2022 also features a #PhDworkshop, at the end of which one of the PhD candidate speakers will be selected for an #award

Photo: @VBoreikaite
(@MRC_LMB), #workshop part 1

@IMPvienna @gmivienna @MaxPerutzLabs @viennabiocenter #RNA #RNAbiology #symposium #PhD

[Yongsheng Shi @YongshengShi]

Very excited to write this Outlook piece with @YoseopYoon for @GenesDev highlighting the groundbreaking work from Elmar Wahle and
@lapassmore groups on reconstituting the human mRNA 3' processing in vitro!
https://t.co/xX0jCO3b1O
https://t.co/XwX2DDpezi
https://t.co/N3FJ3Eyom0

[Lori Passmore @lapassmore]

Vytaute's @VBoreikaite PhD work on reconstituting the activity of the human CPSF complex has now been published online 🎉. @GenesDev https://t.co/d4N9u4vU6S
(see previous thread for details)

[Vytaute Boreikaite @VBoreikaite]

@CJKay93 Done for the day.

[Vytaute Boreikaite @VBoreikaite]

Wordle 210 3/6

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[Lori Passmore @lapassmore]

PolyA tails on eukaryotic mRNAs are added after co-transcriptional endonucleolytic cleavage of the pre-mRNA.
@VBoreikaite has now reconstituted specific and efficient 3ʹ-endonuclease activity by human CPSF with purified proteins. @ERC_Research @MRC_LMB https://t.co/cZGdvu4odW