Varun Venkat

[Science Advances @ScienceAdvances]

Icosahedral RNA viruses rely on essential asymmetries for host cell entry. A new study identifies a unique isopeptide bond that confers a “loaded die” packaging of genomic RNA that steers RNA from the virus particle to the host cell. @GaneshSAnand1 https://t.co/CA3yCtENJW

[Ganesh S Anand @GaneshSAnand1]

Super excited to share this latest paper from my group!

1) Essential asymmetries are critical for steering directional RNA egress and virus infectivity!

2) These essential asymmetries are contributed by a highly specific isopeptide bond!

3) RNA self assembly!

[J. Am. Chem. Soc. @J_A_C_S]

Multiplicity of Regulatory Subunit Conformations Defines Structural Ensemble of Reset Protein Kinase A Holoenzyme | Journal of the American Chemical Society @psu_chemistry @PSUScience https://t.co/LL2hNdvh99