Happy to share our latest study !!
https://t.co/W0KoTkO1W5
We show that behavioral inflexibility is linked to reduced mGluR5 signaling capacity in the dorsolateral striatum, where mGluR5 engages distinct intracellular pathways to regulate tLTD in iSPNs and dSPNs.
I am thrilled to finally present my first Ph.D. research paper, where we delved into the molecular mechanisms behind the decline in behavioral flexibility following extensive training on an appetitive task in mice.
https://t.co/iMVsZVrMga
These discoveries are shedding light on some of the molecular foundations of habit formation and the difficulties associated with adapting to new situations.
If you are interested in the topic keep an eye out for more insights from my Ph.D. research coming out soon.
Happy to finally share our detailed protocol on how to purify afference-specific synaptosome populations using fluorescence-activated synaptosome sorting!
I hope it will help anyone who wants to try to perform FASS
https://t.co/LqQXqQHZHA
Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of ... https://t.co/9dVt8fMTyv #biorxiv_neursci
A fantastic symposium organized by Paul Lapios today. It felt like Christmas before Christmas in MemTraS team.
For those of you in Bordeaux come to his Ph.D defense tomorrow!