@aparanjape Rather than looking like a bull’s nostrils or a kidney grill like earlier, these look like they have the teeth of Bugs Bunny.
Sad fall from the brand’s iconic designs.
@kundu_prashant@wordi25 The only viable solution is to buy an EV 2W/4W for city commute and use the ICE car (new/old) for long rides.
If your city has good public transport, then try to use that as much as possible.
A 23-year-old man from Louisiana, Daniel Cressy, has become the first person in the state to be effectively cured of sickle cell disease through a CRISPR-based gene-editing treatment.
He had lived since childhood with sickle cell disease, a genetic condition that affects the shape of red blood cells. Instead of being round and flexible, the cells become rigid and crescent-shaped, which can block blood flow. This leads to extreme pain episodes, organ damage, strokes, and other serious complications. The disease comes from a single change in the gene that controls haemoglobin, the protein responsible for carrying oxygen around the body.
Because the disorder is caused by a specific genetic mutation, it became an early focus for CRISPR technology, often described as a kind of “molecular scissors” that can edit DNA.
For the treatment, doctors first collected his blood-forming stem cells and sent them to a laboratory. There, scientists used CRISPR-Cas9 to modify the cells, not by directly repairing the faulty gene, but by reactivating the production of fetal haemoglobin, a natural form of haemoglobin present before birth that does not cause red blood cells to sickle.
Once enough fetal haemoglobin is produced, it can take over the role of the faulty adult version and prevent the disease process.
Before the modified cells were returned to his body, doctors used chemotherapy to make space in his bone marrow. After the infusion, the edited stem cells began generating healthy red blood cells.
The therapy, known as Casgevy, became the first CRISPR-based treatment approved for use in 2023 and is seen as a major breakthrough in genetic medicine.
@VirajBake Hi! Thanks for reaching out. That’s not the experience we want you to have. Please share your contact details at https://t.co/Kd7oDKjdJY and we’ll make sure to get it sorted for you.
The best highlights by @ZEE5India from the 2026 FIFA World Cup were from the Norway vs Senegal match because they thought that this match was not important. Hence, the highlights were of 1:52 mins and they forgot to put ads!
Alan Greenspan has died at 100. During his 18½ years leading the Fed, he reached rock-star heights and shaped the U.S. economy under presidents of both parties. Milton Friedman called him the greatest of all time. 2008 recast his legacy.
India holds an estimated one crore manuscripts and more than three lakh stone inscriptions, written across five thousand years and more than a hundred scripts. By volume it is the largest written record any civilisation has produced, and yet less than one per cent of it can be read or searched.
@midf_org describes the country as a civilisational billionaire living in a data-poverty trap.
- @dikshayadav_
Weather Facts #13
Do You Know?
.
☁️ A cloud can weigh 500,000 kg — that’s like 100 elephants in the sky…
And yet it FLOATS 🌤️
Because rising warm air keeps it suspended.
Nature is insane.
In my role over the years, many highly talented people have candidly shared how they’re feeling about their lives and careers.
These days, the feelings of regret, confusion, and FOMO are higher than I’ve ever seen.
While life teaches us better lessons here than anyone else can, here’s something to consider:
You will never make the perfect career decision every time.
And the more talented you are, the greater your accumulated regret about that offer you rejected and that opportunity you didn’t pursue.
So remember this: when you imagine what could’ve gone much better if you’d made a different choice, you will miss seeing what could have gone worse with that choice.
If you are happy and comfortable, imagining how you’d be even happier if only you’d done XYZ or ABC is a guaranteed formula to turn happiness to misery.
#Pune on my plate: How a 25-year-old engineer is reinventing the croissant for India
For Akshay Sanjay Koli, founder of Crosaaintwala & Co, the French pastry is not a foreign indulgence, but a blank canvas waiting to tell an Indian story.
https://t.co/4ziQlZOG6i