Veena S. Anwani

Probe geek.
Chemical Biology,
Ph.D Student at IISER Bhopal.
@iiserbhopal

[Veena S. Anwani @VsAnwani]

@_Tushar_patel Congratulations 🎊

[J. Am. Chem. Soc. @J_A_C_S]

Single-Cell Native Mass Spectrometry for In Situ Detection of Protein–Drug Complexes in Live Cells | Journal of the American Chemical Society https://t.co/VSByu0xdNB

[Veena S. Anwani @VsAnwani]

@AbhilashaBatra @RatiSharma @PhysRevE @iiserbhopal Congratulations 🎊

[J. Am. Chem. Soc. @J_A_C_S]

On the cover of this week's issue: "A Versatile Bioorthogonal Theranostic Platform Enables Relay Activation of Tumor Cell Imaging and Targeted Protein Degradation"

Read it here 🔗 https://t.co/5PhOqeIihH

[Nature Chemical Biology @nchembio]

Activity-based protein profiling identifies covalent small molecules that potentiate the activity of the METTL5:TRMT112 complex through binding to a complexoform-restricted allosteric pocket absent in other TRMT112:methyltransferase complexes

https://t.co/h2xkvN1O1R

[Abhishek Chatterjee @AChemSynBio]

Starting 2026 with Quan Pham's paper expanding the chemical toolbox for engineering AAV
- New bioorthogonal labeling, including IEDDA, for efficient macromolecule attachment
- Incorporation of two different chemistries for dual capsid labeling & much more:
https://t.co/ITupX1fsXq

[Jim Wells @realJimWells]

Check out our most recent temporal MultiMap in print on Nat Chem Biol @nchembio! Using function-orthogonal tags, we applied this molecular photographic labeling technique to monitor dynamic protein neighborhood changes over time. Congratulations to @Zhi_Lindsey_Lin and the team!

[Veena S. Anwani @VsAnwani]

@JhaShivangee Congratulations 🎊 👏 💐

[Dan Nomura @DanNomura]

New from the Cravatt Lab!
Tryptoline stereoprobes reveal hidden cysteine ligandability — while Boltz-2 nails orthosteric sites but burns out on non-orthosteric ones.
Plus: GRPEL1 ligands disrupt its HSPA9 complex, rewiring mitochondrial biology.
A masterpiece of chemoproteomics + AI.

🔗 https://t.co/uwKZG2p9Fz

#ChemicalBiology #Chemoproteomics #Boltz2 #CovalentDrugs

[J. Am. Chem. Soc. @J_A_C_S]

Hijacking Extracellular Targeted Protein Degrader–Drug Conjugates for Enhanced Drug Delivery | Journal of the American Chemical Society @UCSF https://t.co/yVmcmPuB8O

[Guillaume Laconde @Glaconde34]

In Situ PROTAC Synthesis Enabled by Pathologically Activated Bioorthogonal Catalysis for Precision Cancer Therapy | Journal of the American Chemical Society https://t.co/IRNZt3Czry

[Nature Reviews Cancer @NatureRevCancer]

#REVIEW 🚨

Antibody–drug conjugates are rapidly expanding in clinical cancer treatment and in preclinical development. In this Review, Thurber&Co highlight the molecular interactions and immune effects driving #ADC efficacy and toxicity.
📖⬇️
https://t.co/wS841UOGhB

[Xuefeng Jiang @JiangxfGroup]

We built a tunable asymmetric stapling library that:
✅ Precisely controls peptide conformation & function
✅ Enables specific crosslinking of unprotected peptides in complex biological settings
A new tool for chemical biology & drug discovery!
DOI:10.1093/nsr/nwaf406 #Peptide

[Chris Parker @_chrisgparker_]

See our finalized version now out in @angew_chem!

https://t.co/2kBJAG4y4H

[Igor Alabugin @IAlabugin]

What a cool NMR spectrum!
In addition to the negative chemical shift, note how the stereochemical arrangement of H and P strongly influences the coupling constants.

[Vir Das @thevirdas]

I hope India goes to the dogs. For our strays, our Indies, our community dogs 🙏 Wrote in the @timesofindia
Link: https://t.co/0oQUu0V4XL

[Lyndsey Prosser @3LYNDSEY]

Super proud of my best friends and colleagues, Patricia and Ankita! They've worked extremely hard on this project and it shows. You could almost say...it "glows". 💕 https://t.co/Sc5AhqgTlK

[Chris Parker @_chrisgparker_]

Happy to share our contribution to this special issue dedicated to "Proximity-Induced Chemical Biology". We provide our take on targeted protein acetylation.

Nice work Wesley and Roy!

https://t.co/Gp4ggeZIh1

[Yishai Levin @YishaiLevin]

#sp3 digestion protocol automated on the #Waters #andrew robot.
#proteomics

[Arindam Ghosh @ArindamPhysics]

What happened in IISER Kolkata is both heartbreaking and worrying. We need to be more sympathetic and vigilant. Time to monitor mental wellness in educational institutions more systematically by dedicated team of trained professionals, rather than committees of Professors.