Cancer Reports

Cancer Reports is an international, peer-reviewed, OA journal publishing basic, translational, clinical & interdisciplinary research in all aspects of cancer.

[Cancer Reports @Wiley_CancerRep]

Xiong et al. elucidated regulatory axis between METTL14 & VEGFA in hepatocellular carcinoma. METTL14 functions as a critical tumor suppressor by restricting VEGFA-driven angiogenesis via m6A-dependent mRNA destabilization.
https://t.co/R8RrNlzulJ
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Hajivalizadeh et al. reviewed promising pharmacotherapies based on their ability to target core biological mechanisms of cancer-related depression.

https://t.co/agGtjSRxH0

#CancerReports #Wiley #OpenAccess #Review #Cancer #Pharmacotherapy #Depression

@WileyHealth @WileyLifeSci

[Cancer Reports @Wiley_CancerRep]

Mathibela, Lebelo & Steenkamp assessed effects of cisplatin plus phytocannabinoids on cell proliferation, morphology, cell cycle progression, cell death, & DNA damage, in HeLa, SiHa, & MCF-12A cells.
https://t.co/AyejQAtkOx
#CancerReports #Wiley #Cisplatin #Phytocannabinoids

[Cancer Reports @Wiley_CancerRep]

A study by Kawasaki & Kasuyama et al. provides detailed characterization of alterations in estrogen receptor signaling in ER-positive/HER2-negative breast cancers with germline BRCA2pathogenic variants.
https://t.co/2bZMPXubPE
#CancerReports #Wiley #BreastCancer #Germline #BRCA2

[Cancer Reports @Wiley_CancerRep]

Tian et al. identified Helicobacter pylori infection-related genes associated with gastric cancer prognosis & developed prognostic risk model that predicts patient outcomes, tumor immune microenvironment & responses to immunotherapy.
https://t.co/bsmj1Eb8CS
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Okayama et al. report a case with lung adenocarcinoma cT2aN3M1c stage IVB. Patient developed resistance to dabrafenib & trametinib, but responded to pembrolizumab (ICI).
https://t.co/TolxWXbxvw
#CancerReports #Wiley #LungAdenocarcinoma #ImmuneCheckpointInhibitor #Chemoresistance

[Cancer Reports @Wiley_CancerRep]

Takahashi et al. performed retrospective analyses of cancer-specific survival in patients with stage II-III obstructive colorectal cancer. High immune cell infiltration at invasive front associates with favorable prognosis.
Full text: https://t.co/6hz5KGeayo
#Wiley #CancerReports

[Cancer Reports @Wiley_CancerRep]

An et al. showed that DNA hypermethylation in promoter region of ZNF382 & low ZNF382 expression correlate with occurrence & progression of diffuse large B-cell lymphoma.
https://t.co/FMc6FlyXWI
#CancerReports #Wiley #DiffuseLargeBCellLymphoma #DNAHypermethylation #ZNF382

[Cancer Reports @Wiley_CancerRep]

Gadelha et al. analyzed association of WRAP53 & hTERT with clinical outcomes in patients with acute myeloid leukemia (AML). Reduced expression of WRAP53 may serve as biomarker in AML.
https://t.co/qrg4Se2M6R
#CancerReports #Wiley #AcuteMyeloidLeukemia #WRAP53 #Biomarker

[Cancer Reports @Wiley_CancerRep]

Sun et al. performed single-center investigation of safety & efficacy of hypofractionated radiation therapy in patients with spinal metastases. Reduction in pain scores & re-irradiation rates after hypofractioned radiation therapy.
https://t.co/ta4a9GYDwu
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Jin et al. studied the mechanism by which TMEM59L influences 5-fluorouracil sensitivity via PTPRN-mediated DNA damage response in colorectal cancer.
https://t.co/ELwaNsQ3Ik
#CancerReports #Wiley #ColorectalCancer #Chemoresistance #DNADamageRespone #TMEM59L #PTPRN

[Cancer Reports @Wiley_CancerRep]

Song et al. developed universal prognostic model—fatty acid metabolic signature for prognosis (FAMOUS)—as prognostic tool for breast cancer.
https://t.co/mgEVcgnWaK
#CancerReports #Wiley #BreastCancer #FAMOUS #FattyAcid #MetabolicSignature #Prognosis

[Cancer Reports @Wiley_CancerRep]

Patharia et al. developed a diagnostic method leveraging deep learning techniques to enhance accuracy of lung & colon cancer detection.
https://t.co/v9tZYc82mD
#CancerReports #Wiley #CancerDiagnosis #Histopathology #DeepLearning

[Cancer Reports @Wiley_CancerRep]

Mitsui et al. present case study of a patient with metastatic renal cell carcinoma with ocular adnexal metastasis, treated with lenvatinib plus pembrolizumab combinatorial therapy.
https://t.co/NG8D3cO9ak
#CancerReports #Wiley #CaseReport #RenalCellCarcinoma

[Cancer Reports @Wiley_CancerRep]

Kagawa et al. conducted case study to evaluate clinical efficacy & tolerability of afatinib & osimertinib for patients with EGFR L861R-mutated lung adenocarcinoma.
https://t.co/vthBPgZ62n
#CancerReports #Wiley #CaseReport #LungAdenocarcinoma

[Cancer Reports @Wiley_CancerRep]

Yeomans et al. conducted retrospective study to evaluate treatment outcomes in patients with malignant peripheral nerve sheath tumors.
https://t.co/I8OPf9hp82
#CancerReports #Wiley #OpenAccess #MalignantPeripheralNerveSheathTumors #MPNST #Prognosis #Followup #TreatmentOutcomes

[Cancer Reports @Wiley_CancerRep]

Pehlivan et al. investigated association between cigarette smoking & poor sleep in patients diagnosed with cancer, using data from National Health & Nutrition Examination Survey.
https://t.co/UCCimvkouw
#CancerReports #Wiley #Cancer #Smoking #PoorSleep #SmokingCessation

[Cancer Reports @Wiley_CancerRep]

Azadi et al. reviewed the roles of nicotinic acetylcholine receptors (nAChRs) in cancer development with their context-dependent activation & downstream effectors.
https://t.co/t7JFQChn0p
#CancerReports #Wiley #Cancer #NicotinicAcetylcholineReceptor #Therapeutics

[Cancer Reports @Wiley_CancerRep]

Seto et al. assessed correlation between tumor-infiltrating immune cells, expression levels of TGFβ1 & SMAD3, & survival of patients with small cell lung cancer after treatment with immune checkpoint inhibitors plus chemotherapy.
https://t.co/EX3Q0A2yVr
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Haney & Holstein reviewed advantages & shortcomings of osteosarcoma mouse models—transgenic, orthotopic & heterotopic models, and patient-derived xenografts.
https://t.co/qHOSnE5X8j
#CancerReports #Wiley #Review #Osteosarcoma #MouseModel #Preclinical #Therapeutics