Cancer Reports

Cancer Reports is an international, peer-reviewed, OA journal publishing basic, translational, clinical & interdisciplinary research in all aspects of cancer.

[Cancer Reports @Wiley_CancerRep]

Neitzel & Hong showed that inhibition of GPR68 by ogremorphin induces ATF4-dependent ferroptosis in ATRT & that SLC7A11 blockade confers similar sensitivity.
https://t.co/YNHvDdbnrC
#CancerReports #Wiley #BriefReport #AtypicalTeratoidRhabdoidTumors #ATRT #Ferroptosis #GPR68

[Cancer Reports @Wiley_CancerRep]

Liu et al. evaluated role of Dickkopf-1 (DKK1) in regulating ferroptosis & resistance to cisplatin in oral squamous cell carcinoma.
https://t.co/F3HbyUwDh9
#CancerReports #Wiley #OralSquamousCellCarcinoma #Cisplatin #DKK1 #Ferroptosis

[Cancer Reports @Wiley_CancerRep]

Pallatt et al. reviewed mechanisms of senescence-associated secretory phenotype (SASP) induction, its condition-dependent roles in cancer, TME remodeling & emerging strategies targeting senescent cells & SASP signaling.
https://t.co/6RS9GOHD57
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Ikezawa et al. evaluated efficacy & safety of biweekly gemcitabine plus nab-paclitaxel as first-line therapy in patients aged ≥75 years with unresectable prostate cancer.
https://t.co/umGn7IAmR3
#CancerReports #Wiley #UnresectableProstateCancer #OldAge

[Cancer Reports @Wiley_CancerRep]

Pikkarainen et al. evaluated effect of temporalis muscle thickness, measured from head computed tomography scans, on prognosis of patients aged >70 years with brain metastases receiving radiotherapy.
https://t.co/j8cVudxU3T
#CancerReports #Wiley #BrainMetastases #Radiotherapy

[Cancer Reports @Wiley_CancerRep]

Koguchi et al. studied that early evaluation of eosinophil counts can help predict initial & recurrent skin rash in patients who receive apalutamide for prostate cancer.
https://t.co/h9nhQvtLAi
#CancerReports #Wiley #BriefReport #ProstateCancer #Apalutamide #SkinRash

[Cancer Reports @Wiley_CancerRep]

Gong & Xu et al. identified low expression of PKLR to associate with poor survival outcomes in patients with cholangiocarcinoma. Study suggests PKLR to serve as independent risk factor for cholangiocarcinoma.
https://t.co/T9YJTjbARh
#CancerReports #Wiley #Cholangiocarcinoma

[Cancer Reports @Wiley_CancerRep]

Tankul & Hanamornroongruang et al. evaluated correlation between expression of PD-L1 and clinicopathological, surgical outcomes & oncologic outcomes in patients with epithelial ovarian carcinoma.
https://t.co/DXP01WCTH1
#CancerReports #Wiley #OvarianCarcinoma #PDL1

[Cancer Reports @Wiley_CancerRep]

Chou et al. evaluated efficacy & safety of ribociclib & palbociclib as first-line treatments for metastatic hormone receptor-positive breast cancer in real-world settings in Taiwan.
https://t.co/vk66g43Yc0
#CancerReports #Wiley #MetastasticBreastCancer #HormoneReceptorPositive

[Cancer Reports @Wiley_CancerRep]

Othman & Habib et al. reviewed evidence to highlight core principles to modernize cachexia clinical trials. They describe necessity of multimodal approaches: pharmacologic intervention with nutritional support & exercise.
https://t.co/cuGTyD6ip9
#CancerReports #Wiley #Cachexia

[Cancer Reports @Wiley_CancerRep]

Lopetegui-Lia et al. evaluated antidepressant prescribing patterns in patients with breast cancer receiving tamoxifen. Study highlighted variability in prescribing practices, & highlighted importance of individualized, multidisciplinary care
https://t.co/meTGo7ghKP
#CancerReports

[Cancer Reports @Wiley_CancerRep]

Maestri et al. assessed variability of primary ovarian cancer tissues to drug responses using an ex vivo functional profiling platform, and examined its potential to support personalized treatment decisions in clinical practice.
https://t.co/Z2e2vYJlPR
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Flemban et al. retrospectively analyzed long-term trends in kidney cancer burden in Saudi Arabia & compared incidence, mortality, years of life lost & disability-adjusted life years by sex for 1982–2023.
https://t.co/f9WDw0WpEc
#CancerReports #Wiley #KidneyCancer #Epidemiology

[Cancer Reports @Wiley_CancerRep]

Xiong et al. elucidated regulatory axis between METTL14 & VEGFA in hepatocellular carcinoma. METTL14 functions as a critical tumor suppressor by restricting VEGFA-driven angiogenesis via m6A-dependent mRNA destabilization.
https://t.co/R8RrNlzulJ
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Hajivalizadeh et al. reviewed promising pharmacotherapies based on their ability to target core biological mechanisms of cancer-related depression.

https://t.co/agGtjSRxH0

#CancerReports #Wiley #OpenAccess #Review #Cancer #Pharmacotherapy #Depression

@WileyHealth @WileyLifeSci

[Cancer Reports @Wiley_CancerRep]

Mathibela, Lebelo & Steenkamp assessed effects of cisplatin plus phytocannabinoids on cell proliferation, morphology, cell cycle progression, cell death, & DNA damage, in HeLa, SiHa, & MCF-12A cells.
https://t.co/AyejQAtkOx
#CancerReports #Wiley #Cisplatin #Phytocannabinoids

[Cancer Reports @Wiley_CancerRep]

A study by Kawasaki & Kasuyama et al. provides detailed characterization of alterations in estrogen receptor signaling in ER-positive/HER2-negative breast cancers with germline BRCA2pathogenic variants.
https://t.co/2bZMPXubPE
#CancerReports #Wiley #BreastCancer #Germline #BRCA2

[Cancer Reports @Wiley_CancerRep]

Tian et al. identified Helicobacter pylori infection-related genes associated with gastric cancer prognosis & developed prognostic risk model that predicts patient outcomes, tumor immune microenvironment & responses to immunotherapy.
https://t.co/bsmj1Eb8CS
#CancerReports #Wiley

[Cancer Reports @Wiley_CancerRep]

Okayama et al. report a case with lung adenocarcinoma cT2aN3M1c stage IVB. Patient developed resistance to dabrafenib & trametinib, but responded to pembrolizumab (ICI).
https://t.co/TolxWXbxvw
#CancerReports #Wiley #LungAdenocarcinoma #ImmuneCheckpointInhibitor #Chemoresistance

[Cancer Reports @Wiley_CancerRep]

Takahashi et al. performed retrospective analyses of cancer-specific survival in patients with stage II-III obstructive colorectal cancer. High immune cell infiltration at invasive front associates with favorable prognosis.
Full text: https://t.co/6hz5KGeayo
#Wiley #CancerReports