Xiao Li

PhD

[Xiao Li @XiaoLinichd]

4) The OPA1 S158N variant attenuates FA release and associates with metabolic traits in pediatric cancer survivors.
These findings uncover an unexpected mitochondria–lipid droplet regulatory axis linking OPA1 to human metabolism.

[Xiao Li @XiaoLinichd]

New preprint from our team @chiluncellbio : OPA1 doesn’t just regulate mitochondrial fusion — a subpopulation localizes to lipid droplets and actively controls fatty acid release.
https://t.co/1L8AX6moqw.

[Xiao Li @XiaoLinichd]

We show:
1) Exon 4 encodes an amphipathic helix that targets OPA1 to LDs
2) LD-localized OPA1 recruits lipases and promotes FA release
3) LD targeting competes with mitochondrial localization and alters mitochondrial connectivity

[Xiao Li @XiaoLinichd]

@PCLeeWSU @WSUBioSci @sydquag @BrendynStLouis Congrats to PC!

[Journal of Cell Biology @JCellBiol]

.@XiaoLinichd, Gamuyao, @chiluncellbio et al. @stjuderesearch engineer a #LipidDroplet (LD)-targeting motif and develop a tool kit that can track contact sites between LDs and other organelles in living cells. https://t.co/AotgLVvOjm

@Daniel_Stabley @alexcarisey @agtebo

[Xiao Li @XiaoLinichd]

@PCLeeWSU @mbiojournal Congratulations, PC!

[Xiao Li @XiaoLinichd]

@PCLeeWSU He is ready to study legionella😆

[Xiao Li @XiaoLinichd]

@Eric_T_Hall @CellCellPress @lab_ogden @StJudeResearch Congratulations 🎉

[CC_Lab @chiluncellbio]

We are thrilled to introduce FABCON, a “Fluorogen-Activated Bimolecular complementation at CONtact sites” tool kit for interrogating lipid droplet-organelle interaction and beyond in living cells.
https://t.co/8DaroDqX3K

[Xiao Li @XiaoLinichd]

@PCLeeWSU So cute and lovely

[Xiao Li @XiaoLinichd]

@PCLeeWSU @YuTingSu18 @BrendynStLouis @stephlehmanphd @MatthiasMachner Congrats PC! Looking forward to reading it online!

[Matthias P. Machner @MatthiasMachner]

A postdoctoral position in microbial pathogenesis is available in the Machner Lab at NIH.
Help us determine how Legionella pneumophila modulates host cells during infection.
For more details go to
https://t.co/N3EQiHtqZc

[Xiao Li @XiaoLinichd]

@SunnyShinLab @PCLeeWSU @MatthiasMachner Thank you Sunny! ☺️

[Xiao Li @XiaoLinichd]

Interested in how a Legionella phospholipase effector and phospholipids regulate pathogen-containing-vacuole expansion within host cells? Check out our @MatthiasMachner paper! Proceedings of the National Academy of Sciences https://t.co/EFwJbcYktu

[Xiao Li @XiaoLinichd]

@PCLeeWSU @MatthiasMachner Thank you PC. Hope you and your family have a nice Thanksgiving holiday!

[Xiao Li @XiaoLinichd]

@remi_safi @LADYTATA @lipids @Menendez_Lab @AlbertPol10 @CarrerasIJC Congrats Remi🥳🥳🥳

[CC_Lab @chiluncellbio]

Job Alert!
We are hiring postdocs & scientists to interrogate the subcellular spatial organization of metabolism! These positions are supported by DP2 award @NIH_CommonFund and @StJudeResearch offering amazing training opportunities, generous salary/benefits, and GREAT science!

[Xiao Li @XiaoLinichd]

@chiluncellbio @NIHDirector @NIH_CommonFund @NIGMS 🥳🥳🥳

[CC_Lab @chiluncellbio]

The Chang lab @stjuderesearch is looking for highly motivated postdocs and scientists to join us!

We apply innovative tools and approaches to interrogate the dynamic spatial organization of inter-organelle logistics. Details here, https://t.co/8ubraojP2Q

[Xiao Li @XiaoLinichd]

@PCLeeWSU Happy tiger new year!!!