Chengqi Yi

Professor at Peking University.

Yi lab is interested in RNA modifications, Epitranscriptomics and Genome Editing.

Welcome to communicate with us!

[Nature Biotechnology @NatureBiotech]

AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight https://t.co/a9relIlKLC

[Xuemei Chen lab @Xuemei_RNAlab]

A cool technology developed by my colleague Chengqi Yi at Peking University to correct premature termination codon mutations
https://t.co/AoLmdlFqEe

[Chengqi Yi @YiChengqi]

@Xuemei_RNAlab It's my GREAT pleasure to publish the “RESTART” technology as a supported work by BEACON！😁

[Chengqi Yi @YiChengqi]

@Jinghui_Song

[Chengqi Yi @YiChengqi]

Our updated RESTART v3 for premature termination codons rescue @NatureBiotech, which boasts editing efficiency and accuracy. Based on Dr. @Jinghui Song's outstanding work!

https://t.co/9OU9MaRPqM

[Chengqi Yi @YiChengqi]

@NatureBiotech @PKU1898 @Tsinghua_Uni 😝

[Nature Biotechnology @NatureBiotech]

Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons - @PKU1898 https://t.co/0B9bf4hJBe

[Jun-Jie Gogo Liu @GogoLiu]

Thanks Julia. This is an awesome summary of current HYERs!

[Jinghui @Jinghui_Song]

Honored that our RNA base editor "RESTART" has been selected as the best technology of Molecular Cell 2023. Huge thanks to my mentor Prof. Yi (@YiChengqi).
https://t.co/5V5i9VMfSy

[Chengqi Yi @YiChengqi]

SIMPLE-seq @NatureBiotech developed by Dr. Dongsheng Bai @bds1993 et al. that simultaneously detects 5mC and 5hmC at the single-cell and single-molecule level!
Jointly published by Prof. Chenxu Zhu @chenxuzhu from Cornell University and us.
https://t.co/BkLjbajyx3

[Chengqi Yi @YiChengqi]

#RESTART #RNAEditing
We are delighted that RESTART has been recommended as one of the "Best of Cell Press" and published in @MolecularCell . This is a novel and elegant RNA editing tool developed by Dr. @Jinghui_Song et al.
Link to our paper:
https://t.co/qyt28YJvuM

[Chengqi Yi @YiChengqi]

We have witnessed this moment!!!

[Patrick Hsu @pdhsu]

The first approved CRISPR medicine in the world for sickle cell disease and beta thalassemia!

A huge victory for biotechnology, patients, and humanity

https://t.co/hsxHRpPlg1

[Patrick Hsu @pdhsu]

The first approved CRISPR medicine in the world for sickle cell disease and beta thalassemia!

A huge victory for biotechnology, patients, and humanity

https://t.co/hsxHRpPlg1

[Nature Reviews Molecular Cell Biology @NatRevMCB]

🚨 New #NRMCBReview Alert! 🚨

"Regulation and functions of non-m6A mRNA modifications" by Hanxiao Sun, Kai Li, Cong Liu and @YiChengqi

This Review discusses the emerging functional mechanisms and roles of various non-m6A mRNA modifications.
🔗https://t.co/zFV5rpObOo

[Wolf Prize @WolfPrize_]

Congratulations to Chuan He, 2023 Wolf Prize laureate in Chemistry!
@UChiChemistry @UChicago

[JRNLclub @JRNLclub]

Always double check your work. @HermanZhaoZzzz
discusses extensive off-target editing in the nuclear genome induced by a mitochondrial base editor.
@Nature @YiChengqi #JRNLclub https://t.co/txN9siVwLC

[JRNLclub @JRNLclub]

Always double check your work. @HermanZhaoZzzz discusses extensive off-target editing in the nuclear genome induced by a mitochondrial base editor. @Nature @YiChengqi @PKU1898 #JRNLclub https://t.co/5PRjAa8MqF

[Chengqi Yi @YiChengqi]

We are pleased to introduce our new idea of RNA base editing, a safe RNA base editing tool.

Excellent work by Dr. Jinghui Song @Jinghui_Song and Liting Dong!

Click to view the full article
↓

https://t.co/ODqr7SWwCJ

[Jinghui @Jinghui_Song]

So excited to share our work (https://t.co/Mc5PHBLSux). We developed a programmable RNA base editor, termed RESTART in the lab of Prof. Yi (@YiChengqi). Hoping our work will be a promising tool for therapeutics of PTC-disease. https://t.co/hTvD9lnACA

[Chengqi Yi @YiChengqi]

Congratulations to our "GLORI" team!

[Nature Biotechnology @NatureBiotech]

Absolute quantification of single-base m⁶A methylation in the mammalian transcriptome using GLORI - @PKU1898 https://t.co/CpuP72DkWK

[Nature Biotechnology @NatureBiotech]

Absolute quantification of single-base m⁶A methylation in the mammalian transcriptome using GLORI - @PKU1898 https://t.co/CpuP72DkWK