Yorrick Jaspers

PhD Analytical Chemistry | Mass Spec | Metabolomics | Lipidomics | (neuro)metabolic disorders

[YoungNMC @ynmc_benelux]

Are you an Early-Career Researcher (ECR) in the field of Metabolomics?

Come join us on the 2023 YoungNMC Symposium in Nijmegen!

[Stephan Kemp @StephanKempNL]

Population and newborn screening enable disease variant detection and timely treatment. However, screening may also uncover variants of uncertain significance (VUS). Identifying VUS poses a challenge in terms of diagnostic uncertainty and confusion. Free https://t.co/TtD1XSlidF

[TeamALD @ald_team]

Yes, we did it!! Following the highly successful pilot in 2021, the State Secretary of Health, Welfare and Sport (@MinVWS) has decided to add #adrenoleukodystrophy #ALD to the national newborn screening panel from October 1st, 2023.

[RIVM @rivm]

Vanaf 1 oktober 2023 wordt de #stofwisselingsziekte adrenoleukodystrofie (#ALD) toegevoegd aan de hielprikscreening. Het bloed van pasgeboren jongens wordt dan ook getest op ALD. Als de #ziekte op tijd wordt ontdekt, is deze bij jongens behandelbaar.

➡ https://t.co/WSm4jnOuk3

[Prof. Nikolai Slavov @slavov_n]

The heterogeneity of HeLa cell-lines undermines reproducibility.

HeLa cells were obtained without informed consent.

==> Researchers should avoid using HeLa cells unless required by a special justification.

[Nature Reviews Molecular Cell Biology @NatRevMCB]

The lipotype hypothesis - our newest comment from
@Gio_Dangel0 and @GioeleLaManno (@EPFL) on how membrane lipid composition impacts on signalling:

🔗https://t.co/L1VSds8LNh

[TeamALD @ald_team]

The first sex-specific newborn screening program worldwide. Free accessible: https://t.co/2prXFsz64S
Screening of 71 208 newborns resulted in the identification of four boys with adrenoleukodystrophy. The algorithm is ready for nationwide ALD screening in the Netherlands.

[Yorrick Jaspers @YorrickJaspers]

@JIMD_Editors Yes!

[The Journal of Inherited Metabolic Disease @JIMD_Editors]

New in the main journal:

Sex-specific newborn screening for X-Linked adrenoleukodystrophy

Monique Albersen, @FredericVaz, @StephanKempNL et al
https://t.co/3rHSlyU3PA
#visualabstract @ALDConnect @ald_team #ald #xald

[Prof. Nikolai Slavov @slavov_n]

Predictive power of NMR metabolomic profiles for multidisease outcomes https://t.co/zIee1frnL6

The predictions are from 168 circulating metabolic markers measured in 117,981 participants with ~1.4 million person-years of follow-up from the UK Biobank.

[Yorrick Jaspers @YorrickJaspers]

Ron Heeren kicks off #MetSoc2022 with some nice images @mvanweeghel @EMN_MetSoc @ynmc_benelux

[YoungNMC @ynmc_benelux]

The @ynmc_benelux @nlmetabolomics committee pitched during #BenNMC2022 to highlight recent efforts in setting up the #earlycareer #network to foster #metabolomics #training and #ideas! 😎 With many committee members leaving, we are looking for fresh blood to make things happen!

[YoungNMC @ynmc_benelux]

#earlycareer #metabolomics #researchers and other interested #metabolomics scientists! 😎 🌞 You can still sign up for #BeNeLux #Metabolomics #Days on 19 and 20 May in Utrecht, NL! 😎 Please find the full program including @rickdunnblade
@ESchymanski here: https://t.co/sqGG7ZpkYN

[Veera Rajagopal  @doctorveera]

GWAS of brain structural changes across lifespan in 15,640 individuals. "The most robustly identified genes GPR139, DACH1 and APOE are associated with metabolic processes."
https://t.co/Z3z05sUlBK

[Riekelt Houtkooper @rhhoutkooper]

If you want to run polar metabolomics but have no idea where to start, check out our latest paper in @STARProtocols! ⬇️ https://t.co/x1SjicXKie

[Metakids @Metakids]

Onderzoek dat levens redt: vanaf 2023 kan de metabole ziekte ALD in de hielprik worden opgenomen. Met een succesvolle proef zijn al 4 pasgeboren patiëntjes opgespoord. Hoofdonderzoeker Stephan Kemp vertelt: https://t.co/o9aIBtW1i5

[TeamALD @ald_team]

An updated analysis of the known variants in ABCD1 as catalogued over the past 20 years. We illustrate the importance of collaboration and utility of the database as a scientific, clinical, and ALD-community-wide resource. Free: https://t.co/Pxy8UzIsDd @MDPIOpenAccess

[Stephan Kemp @StephanKempNL]

Molecular Biomarkers for Adrenoleukodystrophy: An Unmet Need. The need for sensitive biomarkers to monitor and/or predict disease progression and evaluate therapy efficacy. On https://t.co/8XlKLKHaRC #mdpicells via @MDPIOpenAccess

[Stephan Kemp @StephanKempNL]

Identification of a variant of unknown significance - without a family history of disease - results in a diagnostic dilemma. Biochemical studies in #ALD fibroblasts classified 15/17 VUS in ABCD1 as likely pathogenic/benign. Free at https://t.co/xpOq7sAObK #mdpigenes @Genes_MDPI

[Peter Horvatovich @PHorvatovich]

Dear Colleagues,

I’m looking for a talented colleague in a position of a TT/Associate Professor level entitled “Mass Spectrometry for Analytical Biochemistry” with focus on spatial flux-omics and/or other relevant field of mass spectrometry. See details https://t.co/eF8vIlb8CC