Yunyan Sun

Assistant Professor @ECNUer; Working at the interface of bio/organic/polymer. Interested in molecular design and its applications in bio/organic materials.

[Yunyan Sun @YunyanSun]

@kek_kelsie @IUBChemistry Congrats Kelsie！

[Wang RG @MHWJ9]

My group at RWTH DWI Leibniz institute for interactive materials will have 2 PhD postions open. If you are in polymer chemistry, please send me emails at [email protected]. Details here: https://t.co/VbKhWT6e6L, https://t.co/YUGYL50dxz

[Baran Lab @BaranLabReads]

🚨RADICAL RETHINK: STEREORETENTIVE CROSS COUPLING UNLOCKED🚨 Today in @ChemRxiv (https://t.co/zGZFCsK7aK) the first method for stereoretentive radical cross-coupling is disclosed. No fancy ligands or redox needed—just a Ni-diazene twist. 120 years after Gomberg, a new chapter begins.

Quick summary:
Since Gomberg discovered free radicals over 120 years ago and Kochi pioneered radical cross-coupling in the 1970s, this field has surged with interest for linking C(sp3) fragments. Unlike traditional polar methods (e.g., Suzuki), radical cross-coupling excels with saturated systems, offering mild conditions and chemoselectivity to build complex molecules from common fragments. Until now, enantiospecific radical cross-coupling was deemed impossible due to rapid racemization, but today that changes with readily available sulfonylhydrazides and a simple Ni-catalyst. This stereoretentive approach, enabled by a unique Ni-diazene transition state and driven by loss of N2, skips chiral ligands and redox steps, opening new possibilities for synthesis.

[Huiliang(Evan) Wang @whl0903]

Excited to share our work in @nature on H-bonded organic frameworks as ultrasound-programmable drug delivery system! Congratulations to @wangqenliang92 @advancedlnp @KingRaychard @KaiWTang and all our collaborators! @UTBiomedical @UTAustin @NSF @NIGMS https://t.co/SkoXr2Lwrp

[Yunyan Sun @YunyanSun]

@KevlishviliIlia @BaylorCBC Congrats Ilia!!!

[Yunyan Sun @YunyanSun]

@yuzhengstanford @J_A_C_S Congrats Yu, nice work!

[Yunyan Sun @YunyanSun]

Congrats @Hai_Qian ! Nice approach to tune the force transmission!

[Hai Qian @Hai_Qian]

Thrilled to share our 1st paper in @angew_chem! We introduce a cyclic pulling geometry to tailor force transmission within a mechanophore, enabling modulation of reactivity & the construction of hierarchical mechanophore systems. https://t.co/vPBJfQSt0t #polymer #mechanochemistry

[J. Am. Chem. Soc. @J_A_C_S]

The Restoring Force Triangle: A Mnemonic Device for Polymer Mechanochemistry | Journal of the American Chemical Society @Mechanophore @UofIllinois @BeckmanIllinois #Restoring #Force #Triangle #Polymer #Mechanochemistry https://t.co/8KP9mkrl6h

[Yunyan Sun @YunyanSun]

@MrBSussels @Mechanophore Thanks Ben!

[Yunyan Sun @YunyanSun]

@HirogiY @Mechanophore Thanks!

[Yunyan Sun @YunyanSun]

Check out my last piece of work in my PhD with @Mechanophore! We developed a “cartoon picture” ( a triangle!) to make sense of mechanochemistry under tension. Special thanks to all the reviewers who helped to greatly improved the manuscript! https://t.co/bL5swM5dso.

[Yunyan Sun @YunyanSun]

@Mechanophore @CciMonet Beyond the fundamental insights in the paper, here is one figure I think can be helpful practically (suggested by one kind reviewer!) It tells us the “privileged handles” we should use to incorporate mechanophores.

[Yunyan Sun @YunyanSun]

Many thanks to Jeff who has contributed a ton to this paper! Please make sure to check out the interactive python tool developed by @Mechanophore in the SI!!! Also thank Fangbai who helped to conduct a few simulations. Also thanks the support from @CciMonet

[Yunyan Sun @YunyanSun]

@Mechanophore Thanks Jeff!

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Yunyan Sun @YunyanSun]

@shixuanwei_chem Thanks Shixuan!

[Yunyan Sun @YunyanSun]

@YT_12160 @J_A_C_S @CHEM_Kecheng Thanks Yuting!

[Yunyan Sun @YunyanSun]

Please check out our work @J_A_C_S on Multicolor and White Emission from Mechanically Caged AIEgens. https://t.co/QIVwHReW4T I am glad it is also selected as the ACS Editor’s Choice! This work was done with a phenomenal undergrad @CHEM_Kecheng who will apply for grad school soon

[Yunyan Sun @YunyanSun]

@JunfengZhou2019 @J_A_C_S @CHEM_Kecheng Thanks Junfeng!

[Yunyan Sun @YunyanSun]

@zeyuwang11 @J_A_C_S @CHEM_Kecheng Thanks Zeyu!