Great news from the Apostolova lab @DepBiomedicine! In a recent study led by @ApostolovaPetya & Robert Zeiser (Freiburg, Germany), extracorporeal photopheresis safely treats immune-related adverse events from immune checkpoint inhibitors, with a 92% response rate. Adiponectin helps reduce inflammation while sparing anti-tumor immunity. Congrats! https://t.co/MUaKtbZS1B.
@Cancer_Cell #CancerResearch #Immunotherapy #Collaboration #ECP #ICI #irAE
Researchers in @ZampieriLab@DepBiomedicine developed a method to study how more than 1,500 drugs affect cellular metabolism. Using high-throughput metabolomics, they uncovered new drug mechanisms & potential cancer therapies. Future work will focus on personalizing treatments. @NatureBiotech 🔗https://t.co/0uKHRG5AAB
#Metabolomics #SystemsPharmacology #DrugDiscovery #CellularMetabolism #HighThroughput #PharmaceuticalResearch
We are very excited to share new recent research from our lab! This has been a long-time effort, involving several fantastic group members and collaborators (@pedrobeltrao and @Jürgen) with @LaurentzSchuhk1 on the driving sit.
Thank you European Proteomics Association for the JPA Proteome Pioneer Award in recognition for our group's work in this field. The award promotes "the principles of sharing and integrating resources for the development of excellent research" which is something we do strive for.
It was nice to meet and discuss with all collaborators of the Sinergia grant "Metabolic reprogramming by selective autophagy" from the labs of Fulvio Mario Reggiori and Jörn Dengjel, in Aarhus, Denmark.
In today's journal club, we discussed this comprehensive study on CedA's mechanism of action as transcriptional regulator and its role in mitigating effects of oxidative and antibiotic stress.
https://t.co/sHvP3nmzb8
In our today's journal club:
https://t.co/Qer8QBMHss
The authors demonstrate transcription factor (TF) activities to be predictive biomarkers for genetic dependencies and therefore cancer vulnerabilities.
Check out our new method to read library barcodes and measure metabolites of CRISPRi strains with #massspec. Works almost in real-time: https://t.co/TFrZKIDQyE