Zepeng (Phoenix) Mu

(牟泽鹏) Postdoc @soumya_boston @BrighamWomens @broadinstitute | PhD @yang_i_li @UChicago

[Zepeng (Phoenix) Mu @ZepengMu]

Excited to see the final chapter of my PhD published. Huge thanks to my PhD advisor @yang_i_li, as well as @LB_Barreiro!!!

[Cell Genomics @CellGenomics]

Impact of disease-associated chromatin accessibility QTLs across immune cell types and contexts https://t.co/e1OEfwzkmq

[Soumya Raychaudhuri সৌম্য রায়চৌধুরী @soumya_boston]

So excited to share our latest with Betty Diamond and many colleagues from the AMP RA/SLE consortium, @NIH_NIAMS , and @NIAIDNews ! A large-scale blood and tissue atlas of Lupus Nephritis! https://t.co/c1SAlMnRcu

[Yuriy Baglaenko @YuriyBaglaenko]

I am very excited to share our publication, out now in Nature, detailing our developed CRAFTseq methodology for capturing and analysing single cell genomic DNA amplicons alongside the transcriptome and cell surface protein expression.
https://t.co/rQRubsK58P

[Soumya Raychaudhuri সৌম্য রায়চৌধুরী @soumya_boston]

Join me for this lecture to find out how we use genomics to decipher #autoimmunity and #rheumatoid arthritis

[Saori Sakaue @saorisakaue]

📣Excited to share my last postdoc paper with
@soumya_boston on eQTL mechanisms depending on where the RNA is in the cell! @BrighamResearch @broadinstitute
TL;DR:Early RNA eQTL variants in the nucleus and late RNA eQTL variants in the cytosol have distinct molecular mechanism🧵👇

[Yoav Gilad @Y_Gilad]

My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. It’s available on Amazon: https://t.co/VKR3l4RTSA

[Zepeng (Phoenix) Mu @ZepengMu]

Huge thanks to my PhD advisor @yang_i_li and all collaborators especially @LB_Barreiro for their help and support!!! Huge thanks to all the donors! This data is a subset of a larger scRNA/scATAC data, read more about the cool discoveries in threads from @he_randolph!

[Zepeng (Phoenix) Mu @ZepengMu]

Excited to share the final chapter my PhD research on @medrxivpreprint! eQTLs only explain 30% of GWAS loci and 11% of trait heritability. Here we investigate if epigenetic QTL can provide new insights at the remaining GWAS loci. https://t.co/vzkyjbTdkC

[Zepeng (Phoenix) Mu @ZepengMu]

To conclude, we believe it is crucial to continue studying the genetic regulation of molecular phenotypes in more disease-relevant contexts. Furthermore, we emphasize the necessity of integrating various functional assays to elucidate causal mechanisms at GWAS loci.

[Xuanyao Liu @XuanyaoLiu]

Our work is out in AJHG! I wholeheartedly thank all the co-authors @marie_saitou @andywdahl @qbw_128 for their time and effort! All four of us started our own labs between 2019 and 2021 and the pandemic didn't make things easy. Super proud of everyone.

[Jinghui Li @JinghuiLi14637]

Our work on trans regulation of proteome and how protein-protein interactions play a role in it🧬.

[Haley Randolph @he_randolph]

check out our review discussing immune diversity through the lens of evolutionary biology!

we argue that past selection underlies variation in disease risk across populations and offer new avenues to pursue that couple empirical and genomics approaches

https://t.co/v8SmOHhcOp

[Xuanyao Liu @XuanyaoLiu]

Our work led by @liliw_wang on identifying trans genetic effects of gene networks is out in @CellGenomics today!

[Yuriy Baglaenko @YuriyBaglaenko]

CRISPR editing is hard. Editing in primary human cells is even harder. Editing non-coding variants in human cells is downright impossible. I am happy to share our work aimed at addressing this problem with @soumya_boston @broadinstitute @MassGenBrigham https://t.co/zsH9UYd4cj