Zuxiao Zhang Group

Welcome to the Zhang Lab at the University of Hawaii at Manoa, where our focus lies in pioneering novel catalytic systems.

[Zuxiao Zhang Group @ZhangLabUHM]

Turn simple alkenes into high-value allylic CF₂R motifs, our hybrid Pd-catalyzed, redox-neutral difluoroalkylation delivers broad scope, excellent regio/stereocontrol, and even repurposes Freon-22! https://t.co/HuR6eh8kD8

[Zuxiao Zhang Group @ZhangLabUHM]

New chemical discovery could speed up future medicines, materials https://t.co/n7woLZFgV2

[Zuxiao Zhang Group @ZhangLabUHM]

Thrilled to share our latest work in Angew. Chem.: Deoxygenative Difunctionalization of Aldehydes via Ketyl Radical & Light/Dark Pd Synergy 🎉

Read morehttps://onlinelibrary.wiley.com/doi/10.1002/anie.202521847

[Zuxiao Zhang Group @ZhangLabUHM]

We report a visible-light Pd-catalyzed multicomponent strategy for the convenient synthesis of isoquinuclidines, valuable sp³-rich scaffolds for drug discovery.

🎉 Congrats to the team!

🔗 https://t.co/UIzjRIC8E4

#OrganicChemistry #Catalysis #DrugDiscovery

[Zuxiao Zhang Group @ZhangLabUHM]

New chemistry alert! Allylic C–H Difluoroalkylation of Unactivated Alkenes with Trifluoromethylarenes | ACS Catalysis https://t.co/oiVjzBpkB1

[Zuxiao Zhang Group @ZhangLabUHM]

@nagiblab @ScienceMagazine Congratulations!!!

[Zuxiao Zhang Group @ZhangLabUHM]

@ChemJChu @J_A_C_S 祝贺师兄！

[Zuxiao Zhang Group @ZhangLabUHM]

Exciting news! Our recent work has been highlighted in SYNFACTS for its important insights in synthetic chemistry! Huge thanks to my co-authors and the @ThiemeChemistry team. https://t.co/Brl1YITKJf

[Zuxiao Zhang Group @ZhangLabUHM]

Thrilled to share our latest in @Org_Lett! 🚀 Photocatalytic alkylazolation of alkenes enables efficient C–C & C–N bond formation, crafting aza-heterocycles for drug discovery. Congrats, Tiancen! 🎉https://t.co/Pjs6ItOtp1

[Zuxiao Zhang Group @ZhangLabUHM]

Excited to share our latest breakthrough in synthetic chemistry! 🚀 Jing and Qixin's hard work led to a Pd-Catalyzed Difluoroalkylation of Alkenes Using Chlorodifluoroalkanes | ACS Catalysis https://t.co/ZOeaL1Fxmr

[Zuxiao Zhang Group @ZhangLabUHM]

📢 New paper alert! We've developed a hybrid Pd-catalyzed method for selective defluorination of ArCF3, paving the way for efficient functionalization of trifluoromethylated arenes! 🚀 https://t.co/rJMdvGOwCL

[Zuxiao Zhang Group @ZhangLabUHM]

🚀 New breakthrough! We found a way to transform Freon-22 into valuable, harmless chemical building blocks! 🌱

Congrats to Qixin Jing and team on our visible-light, Pd-catalyzed method for 1,4-difluoromethylation of conjugated dienes using Freon-22. https://t.co/bq3Pjc3q4R

[Zuxiao Zhang Group @ZhangLabUHM]

Hybrid Palladium-Catalyzed Intramolecular Carboamination of Conjugated Dienes: Synthesis of Functionalized Pyrrolidines via Selective Trifluoromethylarene Defluorination | The Journal of Organic Chemistry https://t.co/izKiWlf89f

[Zuxiao Zhang Group @ZhangLabUHM]

Discovery could lead to more effective drug treatments https://t.co/CE7ncOjXJN

[Zuxiao Zhang Group @ZhangLabUHM]

Discover innovative insights in our latest publication on synthesizing challenging 1,4-cis-disubstituted cyclic compounds: Selective 1,4-syn-Addition to Cyclic 1,3-Dienes via Hybrid Palladium Catalysis. @ACSCentSci https://t.co/XnWlxrISLy

[Zuxiao Zhang Group @ZhangLabUHM]

@OrgBiomolChem @dirac1231 @StudyatZJNU Nice work!

[Zuxiao Zhang Group @ZhangLabUHM]

@OrgBiomolChem @dirac1231 @StudyatZJNU Nice work