Jess Davidson

ultra runner + mom + metabolism nerd + aspiring neuroscientist, postdoc at UW Madison (she/her)

[Jess Davidson @_JessDavidson]

Excited to share our latest story on the regulation of lysosomal BMP lipids! Co-led with Raghav Jain, we show that PLA2G15 is a BMP hydrolase that regulates lipid levels under the transcriptional control of TFEB.
@JudithSimcox @UWBiochem @HHMINEWS

[Cell Metabolism @Cell_Metabolism]

New! Online now: Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV https://t.co/QcT4tpbNWl

[UW-Madison IPiB @uwmadisonipib]

Join us for Jess Davidson's Ph.D. thesis defense on April 16! Her research in the @JudithSimcox Lab explored how lipids are regulated under conditions of metabolic stress, such as cold exposure and disease. Learn more: https://t.co/1GmV8rLS9g

[Judith Simcox PhD @JudithSimcox]

Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.

[Judith Simcox PhD @JudithSimcox]

Great work by Mugagga, @LainyVonBank and @_JessDavidson from the Simcox Lab! SCD1 is known to regulate the production of monounsaturated fatty acids and development of diabetes in response of high carbohydrate diet. We showed loss of SCD1 also controls acylcarnitine levels.

[Eddie Rashan @EdreesRashan]

As promised, a 🧵 on our recent article now out in @NatureSMB! Co-led with @AbbyBartlett_ @Pagliarini_Lab @JudithSimcox, we find ACAD10/11 are NOT like other acyl-CoA dehydrogenases and instead catabolize atypical lipids called 4-hydroxy acids 🤯#lipidtime https://t.co/u1E4kniIso

[Eddie Rashan @EdreesRashan]

AHH!! My primary thesis work is finally out! Tweetorial to come...

[Jess Davidson @_JessDavidson]

30 mile ride to celebrate 30 weeks of pregnancy 💪🏼 pretty stoked with how this cell culture experiment is going so far!

[UW-Madison Graduate School @UWMadGSEd]

Congratulations to Dr. Andrea Hunger on receiving the WISL Award for Communicating PhD Research to the Public! Dr. Hunger's thesis chapter explores novel genetic regulators of metabolism. https://t.co/CWD3o4WglJ

[Wei Lab@wisc @Wei_Lab_WISC]

My lab is recruiting a postdoc fellow to characterize new biochemical pathways that control taurine and glucose metabolism. Email me at [email protected] to apply! Please help RT🙏 @longlabstanford @JudithSimcox @UWBiochem

[Jess Davidson @_JessDavidson]

@YutongBao @JudithSimcox @UWBiochem @HHMINEWS Thanks, Yutong!

[Jess Davidson @_JessDavidson]

Excited to share our latest story on the regulation of lysosomal BMP lipids! Co-led with Raghav Jain, we show that PLA2G15 is a BMP hydrolase that regulates lipid levels under the transcriptional control of TFEB.
@JudithSimcox @UWBiochem @HHMINEWS

[Cell Metabolism @Cell_Metabolism]

New! Online now: Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV https://t.co/QcT4tpbNWl

[Jess Davidson @_JessDavidson]

@WeiWei_Stanford @JudithSimcox @UWBiochem @HHMINEWS Thank you!!

[Jess Davidson @_JessDavidson]

5/ There are still many unanswered questions on PLA2G15 post-translational regulation and stereoisomer specificity for BMPs to be explored in the future. But this is a huge step forward for the field and I’m thrilled to be a part of such impactful, collaborative research.

[Jess Davidson @_JessDavidson]

4/ This is exciting, as PLA2G15 was identified as a BMP lipid hydrolase not only by us but also in recent work from our collaborators in the @abu_remaileh lab who further characterized PLA2G15 as a potential therapeutic target in NPC disease.

[Jess Davidson @_JessDavidson]

Stoked for the opportunity to share some of my translational research with the Biochemistry community at the University of Utah next week!

[U of Utah Dept of Biochemistry @UofUBiochem]

We will be welcoming nine talented Graduate Student Rising Stars to share their research with us on Monday May 19th, starting at 9:30am in HSEB 1730. The symposium will be followed by the Pace Keynote talk by Dr. Toto Olivera at 4pm!

[UW-Madison IPiB @uwmadisonipib]

Please join us on May 19 for Andrea Hunger's Ph.D. thesis defense! Hunger's research in the @JudithSimcox Lab examined the regulation of a lipid that controls cell death and insulin signaling. Learn more: https://t.co/dzml95fBSY

[UW-Madison IPiB @uwmadisonipib]

Join us for Gina Wade's Ph.D. thesis defense on May 2! @JustWadeAMinute's research in the @JudithSimcox Lab examined the role lipids play in regulating body temperature during cold exposure. Learn more: https://t.co/zEAvxqOnob

[Wei Lab@wisc @Wei_Lab_WISC]

I'm beyond thrilled to announce that I will be joining the Biochemistry Department at the University of Wisconsin–Madison this fall as an Assistant Professor. My lab will focus on deorphanizing biochemical pathways that regulate nutrient metabolism @UWBiochem @uwmadisonipib