⚠️ AT&T is currently experiencing a cellular outage along the Huntington–Charleston I-64 corridor and parts of southern WV. This may impact some WV 511 camera feeds.
Psilocybin made human cells live 50% longer.
A new study has uncovered surprising anti-aging potential in psilocin—the active metabolite produced when the body breaks down psilocybin, the psychoactive compound found in magic mushrooms.
In laboratory experiments, researchers exposed two human cell lines (skin fibroblasts and fetal lung fibroblasts) to a 100 μM concentration of psilocin. The results were striking: lung cells took 57% longer to reach replicative senescence (the point at which cells permanently stop dividing and accumulate damage), while skin fibroblasts extended their replicative lifespan by 51%.
These findings suggest psilocin may slow fundamental cellular aging processes, possibly by lowering oxidative stress, enhancing DNA-repair pathways, supporting mitochondrial health, or dampening chronic inflammation—mechanisms that overlap with those targeted by leading experimental longevity drugs.
The benefits extended beyond cell culture. In aged female mice (19 months old at the start, equivalent to approximately 60–65 human years), a single monthly dose of psilocybin dramatically improved outcomes. After 10 months of treatment, 80% of the psilocybin-treated animals remained alive, compared with only 50% of untreated controls. Treated mice also displayed markedly fewer visible signs of aging, including reduced fur loss and graying.
This research marks the first direct demonstration that psilocybin/psilocin can influence biological aging itself, rather than solely producing psychological effects. The authors emphasize that the study used relatively conservative dosing and are now advocating for follow-up work with higher or more frequent administration, detailed assessments of immune, metabolic, and cognitive function, and investigations into whether the extended lifespan corresponds to genuine improvements in healthspan and quality of life.
["Psilocybin treatment extends cellular lifespan and improves survival of aged mice." npj Aging, 2025]
@RAKwireless Was just about to buy a CutiePi then noticed RAK had a WisTablet in the works 👀
You wouldn't happen to be able to give me a rough release date estimate, would you? Or tell me how it would compare to the CutiePi? 🙏
Thanks!
@nuphystudio I already have one of these - but I would do anything for this exact keyboard, split with a cord between the two halves. Like the Keychron Q11, but slim and travel-ready like the Air75 V3.
Starting to think I might actually be 7w6 and not 6w7, and that's why the type 6 memes never quite hit for me. I thought it was because I am the countertype (I'm sx/sp).