aay kay

[Tim Healthy lifestyle 🏋️‍♀️ @clint_timmy]

Put turmeric on a boiled egg and watch what happens

[𝙋𝙚𝙖𝙠 𝙈𝙖𝙨𝙘𝙪𝙡𝙞𝙣𝙞𝙩𝙮 @PeakMasculinit]

8 Supplements That Transform Men With Low Testosterone Levels into True Charms (Men Over 30: This Is For You)

1. Chelated Zinc (the testosterone mineral)

[Dear Men. @DearM_e_n]

7 Daily Foods That Give You Rock-Hard Erections & Beast Mode Stamina

(Your girlfriend will thank you)

1. Watermelon

[رضوانہ @Rizvana_Raza]

Such a beautiful girl could be from Iran or Pakistan

[Lore GuerreroX @HumanaCuriosaX]

10 Hábitos Que Convierten a los Hombres con Baja Testosterona en Bestias de Alta Testosterona.

(Hazlos Todos los Días)

1. Come huevos (La Fábrica de T)

[IRAN ARMY ☫ @IranArmySpoofX]

Muslim women have always been considered among the most beautiful women in the world.

That's why some non-Muslims have a problem with the burqa—Because they want to see Muslim women's faces.

[Mohammad Khuroo @mskhuroo]

Salt Tea (Noon Chai) and Cancer Esophagus in the Kashmiri Population: Cause and Effect.
Dear Viewers: Let Science speak for itself.
The data that form the basis of these statements have been meticulously collected over decades. These are published in high-ranking International Journals and are heavily cited by the International medical fraternity. Each statement is followed by a supportive publication.
Disease Burden
The incidence of esophageal cancer in Kashmir is among the highest in the world. The age-standardized incidence rate (ASIR) in the valley is 43.6 per 100,000 per year for men and 27.9 per 100,000 for women. (1) The burden of esophageal cancer in Kashmir is 3 to 6 times higher than in other major Indian metropolitan areas and the West. However, the incidence in Kashmir is comparable to other regions within the Asian Cancer esophagus belt, such as the Caspian littoral of Iran and the Henan and Shanxi provinces of China. (1) We have evidence that healthy adults have a high occurrence of esophagitis, dysplasia, and carcinoma in situ, which finally culminates in cancer. The data generated show that extensive exposure to nitrates and aliphatic amines in food items is related to the occurrence of cancer in this population. (2, 3) In a meticulously conducted case-control study, five food items were associated with esophageal cancer. These include 1. Salt tea (>5 cups per day; OR 5.93), 2. Smoking (OR 4.75), 3. milk (<30 g/day; OR 1.92), 4. fats/oils (>30g/day; OR 1.92), and 5. fruits (<6 times/month; OR 2.40). (4)
The consumption of Salt Tea (Noon Chai) is considered a critical risk factor in the pathogenesis of esophageal cancer in Kashmir, a region with an exceptionally high incidence of the disease. (2, 5-7) Research indicates that the unique preparation and heavy consumption of this beverage contribute to a biological progression from chronic inflammation to malignancy. (8, 9)
Pathological Progression
The evolution of esophageal cancer in the Kashmiri population follows a well-defined pathological sequence that typically takes 20 to 30 years to culminate in frank cancer:
1. Chronic Esophagitis: A study of 107 healthy volunteers revealed that 75% of the adult population had histological evidence of chronic, non-reflux esophagitis. This inflammation is asymptomatic and results from continuous injury to the esophageal epithelium. (10)
2. Mucosal Changes: Continued irritation leads to more advanced changes, including acanthosis and atrophy.
3. Dysplasia: Approximately 10% of healthy volunteers showed signs of dysplasia, a precancerous state where tissues undergo abnormal changes. (10)
4. Carcinoma in Situ: This is the final stage before the development of invasive cancer, found in about 2% of the asymptomatic population studied. (5, 6, 10, 11)
The Role of Salt Tea (Noon Chai)
Noon Chai is the most popular beverage in Kashmir, with many individuals consuming up to 10 cups per day. A case-control study determined that consuming more than 5 cups per day carries an odds ratio of 6 for developing esophageal cancer. (1) The pathogenesis involves several chemical and physical factors:
• Endogenous Nitrosation: The preparation of Noon Chai involves brewing green tea leaves with sodium bicarbonate (soda) until a thick red-brown extract is formed, to which salt and milk are added. This process creates highly reactive precursors. (9)
• Caffeine-Derived Carcinogens: Pure caffeine, when treated under these specific tea-preparation conditions, forms caffeidine and caffeidine acid. Upon nitrosation (simulating gastric conditions), these form two potent N-nitroso compounds: mononitrosocaffeidine (an asymmetric nitrosamine) and dinitrosocaffeidine (an N-nitrosamide). Mononitrosocaffeidine has been specifically identified in typical Kashmiri salted tea.(12, 13)
• High Methylating Activity: Salted tea shows high methylating activity, equivalent to 3 p.p.m. N-methylnitrosourea, a known carcinogen.
• Exposure to Amines and Nitrates: Frequent consumption results in exceptionally high exposure to aliphatic amines such as methylamine (1200 µg/day) and ethylamine (14,320 µg/day), which can react endogenously to form carcinogenic nitrosamines. (13)
• Irritants and Thermal Injury: The tea is traditionally drunk boiling hot, potentially causing thermal injury to the esophagus. Furthermore, common salt (NaCl) is a known irritant to the gastric and esophageal epithelium and may enhance the effects of other carcinogens. (7)
Synergistic Factors
While salt tea is a primary factor, its impact is often compounded by other local habits. For example, smoking tobacco through a hubble-bubble (Jajeer) and a diet high in sun-dried vegetables (Hakh) and red chili cakes (Wur) also contribute to the high intake of nitrates and amines, further driving the progression from esophagitis to squamous cell carcinoma. (4, 14-18)
References
1. Khuroo MS, Zargar SA, Mahajan R, Banday MA. High incidence of oesophageal and gastric cancer in Kashmir in a population with special personal and dietary habits. Gut. 1992;33(1):11–5.
2. Tricker AR, Preussmann R. Carcinogenic N-nitrosamines in the diet: occurrence, formation, mechanisms and carcinogenic potential. Mutat Res. 1991;259(3-4):277–89.
3. Siddiqi M, Kumar R, Fazili Z, Spiegelhalder B, Preussmann R. Increased exposure to dietary amines and nitrate in a population at high risk of oesophageal and gastric cancer in Kashmir (India). Carcinogenesis. 1992;13(8):1331–5.
4. Thesis. “Diet and risk of cancer of the esophagus in Kashmir: a case-control study. A thesis was submitted to the Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, for the award of the MD (General Medicine) degree in the 1993 session.
5. Khuroo MS, Khuroo NS. Status report: Cancer of the esophagus in Kashmir. JK Practitioner. 2000;7(2):145–8.
6. Siddiqi M, Preussmann R. Esophageal cancer in Kashmir--an assessment. J Cancer Res Clin Oncol. 1989;115(2):111–7.
7. Khuroo MS. Esophageal Cancer in Kashmir: An overview. Greater Kashmir: A daily English Newspaper [Internet]. 2023. Available from: https://t.co/q7eiBIEybn (https://t.co/q7eiBIEybn).
8. Siddiqi M, Tricker AR, Preussmann R. Formation of N-nitroso compounds under simulated gastric conditions from Kashmir foodstuffs. Cancer Letters. 1988;39(3):259–65.
9. Siddiqi M, Tricker AR, Preussmann R. The occurrence of preformed N-nitroso compounds in food samples from a high-risk area of esophageal cancer in Kashmir, India. Cancer Letters. 1988;39(1):37–43.
10. Goswami KC, Khuroo MS, Zargar SA, Pathania AG. Chronic esophagitis in a population (Kashmir) with high prevalence of esophageal carcinoma. Ind J Cancer. 1987;24(4):232–41.
11. Thesis. Role of personal and dietary habits in the etiology of premalignant lesions and malignant tumors of the esophagus.” Thesis submitted to Sheri-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, for the award of the degree MD (General Medicine) in the session 1992.
12. Kumar R, Mende P, Wacker CD, Spiegelhalder B, Preussmann R, Siddiqi M. Caffeine-derived N-nitroso compounds--I: Nitrosatable precursors from caffeine and their potential relevance in the etiology of oesophageal and gastric cancers in Kashmir, India. Carcinogenesis. 1992;13(11):2179–82.
13. Ivankovic S, Seibel J, Komitowski D, Spiegelhalder B, Preussmann R, Siddiqi M. Caffeine-derived N-nitroso compounds. V. Carcinogenicity of mononitrosocaffeidine and dinitrosocaffeidine in bd-ix rats. Carcinogenesis. 1998;19(5):933–7.
14. Tricker AR, Siddiqi M, Preussmann R. Occurrence of volatile N-nitrosamines in dried chilies. Cancer Lett. 1988;38(3):271–3.
15. Katiyar S, Hedau S, Jain N, Kar P, Khuroo MS, Mohanta J, et al. p53 gene mutation and human papillomavirus (HPV) infection in esophageal carcinoma from three different endemic geographic regions of India. Cancer Letters. 2005;218(1):69–79.
16. Kumar R, Mende P, Tricker AR, Siddiqi M, Preussmann R. N-Nitroso compounds and their precursors in Brassica oleracea. Cancer Letters. 1990;54(1):61–5.
17. Tricker AR, Kumar R, Siddiqi M, Khuroo MS, Preussmann R. Endogenous formation of N-nitrosamines from piperazine and their urinary excretion following antihelmintic treatment with piperazine citrate. Carcinogenesis. 1991;12(9):1595–9.
18. Siddiqi M, Tricker A, Kumar R, Fazili Z, Preussmann R. Dietary sources of N-nitrosamines in a high-risk area for oesophageal cancer--Kashmir, India. IARC scientific publications. 1991(105):210–3.

[Dr Tariq Tramboo @tariqtramboo]

What comes to your mind after reading this?

[Arfa Khanum Sherwani @khanumarfa]

मुसलमान रोड पर योगा कर सकता है लेकिन नमाज़ नहीं पढ़ सकता 👏🏼👏🏼

[سليمان الفهد @SulaimanALFAHD1]

#الصين

الصين تعرض #ذبابا_مقاتلا - طائرات بدون طيار صغيرة مثل الحشرات للتجسس الخفي!

يبلغ وزنها أقل من 0.3 جرام، وتهز أجنحتها ما يصل إلى 500 مرة في الثانية، ويمكنها حمل أجهزة استشعار صغيرة للمراقبة.

ولكن هناك عيب واحد - قد تعصف بهم الرياح.

#سليمان_الفهد

[Aditya Raj Kaul @AdityaRajKaul]

Trump: "If [the Iran deal] works out, I'm going to take the credit; if it doesn't work out, I'm blaming JD [Vance]."

Interesting to see Marco Rubio’s straight face reaction while Lutnick just can’t stop laughing!

[Sexual Health coach @sxhealth101]

If you are a man 40+ years old, these supplements should never be missing in your house:

• Zinc → Supports testosterone production and sperm health
• Magnesium → Improves sleep, recovery, and circulation
• Vitamin D3 + K2 → Supports hormones and overall health
• Omega-3 → Promotes healthy blood flow and heart health
• L-Citrulline → Helps increase nitric oxide for better circulation
• Ashwagandha → Helps manage stress and supports hormone balance
• CoQ10 → Supports energy production and sperm quality

Your sexual health at 40 always begins to deteoriate this supplements will save you.

[Dr Ranjan @DocRGM_]

Corrupt from Top to Bottom...

[Dr Tariq Tramboo @tariqtramboo]

Note: Your body doesn't naturally make vitamin B12. That means you have to get it. Naturally occurring B12 is not found in plants.

[القرآن @Quranconnect_]

Yaa Allah I got goosebumps 🥹❤️❤️.

[Allah Islam Quran @AllahGreatQuran]

Remember Allah, wherever you are.

[IndiaToday @IndiaToday]

Senior journalist @sardesairajdeep shared a light-hearted reaction to the growing online buzz around the Cockroach Janta Party, saying he may be “too old to join” the satirical movement, but still considers himself “a Cockroach.” His remarks come amid the outfit’s rising popularity across social media platforms.
#RajdeepSardesai #CockroachJantaParty #CJP #PoliticalSatire #SocialMedia #DemoraticNewsroom

[𝐌𝐚𝐡𝐝𝐢 @Mahdii_365]

SubhanAllah!

[The Trading Wolf @TheTradingwolf0]

🚨 BIG CRISIS ALERT ‼️

🏦 People across India are suddenly pulling huge amounts of cash out of banks 💸

📌 Indians withdraw ₹61,000 Crore in just 15 days as currency circulation rises 📈

📌 Crosses ₹42 lakh crore amid rising distrust in digital banking 📲⚠️

📌 Signal of growing fear 😟 & loss of trust in digital systems 🌐

💡 Are you prepared? Keep some cash 💵 Stay alert 🚨

✅ Financial stability starts with smart choices.

#Bigcrisis