Anna Bagnell

PhD student @HopkinsMedicine + @Sumnerlab studying TRPV4 neuropathies | @UofSC alum |

[Anna Bagnell @abagnell_sci]

"Treatment with a TRPV4 antagonist inhibited barrier leakage and reversed pathology, suggesting a therapeutic strategy to treat TRPV4 associated motor neuropathies!"

[Anna Bagnell @abagnell_sci]

After many years of amazing work, Dr. Jeremy Sullivan's paper (@SumnerLab ) is finally out and TRPV4 expression in brainstem blood vessels made the cover!

https://t.co/wnkws3Ljuc

[Science Translational Medicine @ScienceTM]

This week's new issue of #ScienceTranslationalMedicine has arrived!

Epigenetic clues can predict the risk of kidney failure in patients with type 1 diabetes, an experimental antiviral neutralizes an array of coronaviruses in mice, and more. https://t.co/NE70MeaFWb

[Anna Bagnell @abagnell_sci]

"Sullivan et al. used mouse models to show that TRPV4 gain-of-function mutations in endothelial cells led to focal disruptions of blood–spinal cord barrier, motor neuron loss, and the development of neurological symptoms resembling motor neuropathies."

[John Lukens @LukensJohnR]

Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice
https://t.co/fbDkBHZyhK

[Anna Bagnell @abagnell_sci]

@madamscientist @CMM_JHU @JohnsHopkins @SumnerLab @HopkinsMedicine Thank you Rajini!!!

[Nature Biotechnology @NatureBiotech]

Lighting the match: how a student-led career mentorship program can blaze the way for non-academic careers https://t.co/GK8xKpnp1O

[Anna Bagnell @abagnell_sci]

@willaise @jonathan_alevy 👀

[Anna Bagnell @abagnell_sci]

@sblizarraga @BrownUniversity @BrownMolBio @brown_ctn @BrownUNeuro @DrJudyLiu @TheWebbLab @YAlvinHuang Congrats Sofia!! So excited for you!

[Anna Bagnell @abagnell_sci]

@dude__itsme @HHMINEWS @AshaniTW Congrats Alexis!!!

[Anna Bagnell @abagnell_sci]

@LinvilleRaleigh @MIT_Picower Congrats Raleigh!!!

[Anna Bagnell @abagnell_sci]

@TracyD_Chung @SearsonGroup Congrats Tracy!!

[Care4ASH1L @Care4ASH1L]

Today is ASH1L Awareness Day. At Care4ASH1L, our mission is to raise funds to help facilitate ASH1L research in order to find a cure or a therapeutic intervention to ameliorate the lives of those affected.
Please donate at https://t.co/tkL93GuWMz

[Anna Bagnell @abagnell_sci]

@willaise Thanks will!!

[Anna Bagnell @abagnell_sci]

@willaise @SumnerLab This is cool!!! Sending this Brett's way 👀

[Anna Bagnell @abagnell_sci]

@sblizarraga @UofSCBiology Congrats Sofia and to all of the Lizarraga lab!! So excited to see this work published and to have had the opportunity to contribute to this research with my @SCHonorsCollege thesis 🎉

[Dr. Sofia Lizarraga 🇵🇪🇺🇦 @sblizarraga]

Excited to share our work on ASH1L in human neuronal development!! 🧬🧠 @ Molecular Psychiatry https://t.co/NvCFVuoPK9 🥳 🥳 Congratulations to awesome co-1st authors twitterless Sunny Cheon & Allie Culver & all co-authors (next tweet)!! https://t.co/wVqNNSwtQn @UofSCBiology

[Anna Bagnell @abagnell_sci]

@willaise @SumnerLab @jonathan_alevy Yay!! Congrats Will! Time for me to dispose of the leaning tower of western blot boxes in the deli fridge lol

[Vince Buffalo @vsbuffalo]

The subject of this painting is Christina Olson, Wyeth's neighbor and friend. Olson developed a degenerative muscle condition and preferred crawling —as depicted— rather than a wheelchair. The MOMA has a great video exploring this piece and disability: https://t.co/uZTGDnOGTs

[Anna Bagnell @abagnell_sci]

@LinvilleRaleigh I sometimes use this database to compare mouse endothelial transcriptomes from the brain, heart, and lung! https://t.co/RlEF6o6Ipk

This database is also useful in comparing gene expression in different regions/cell types of the mouse brain: https://t.co/Lay2xkUDz1