Read more about our study in the full manuscript to learn how BTI influences T cell immunity against SARS-CoV-2 variants.
https://t.co/asf8yfeST9
Stay tuned for updates on our research! 8/8
We also identified novel epitopes recognizing variant-specific mutations, accounting for 9-15% of the total epitope repertoire. This indicates that the T cell response is responding to variant evolution and is able to generate new responses to the evolving virus. 7/8
I’m honored to receive this award from @ItalyMFA_int recognizing my contributions as a woman in science. It was a great opportunity to meet fellow award winners representing Asia and Africa and discuss our work together. Grazie mille! #scienceshesays
Congratulations to LJI Postdoc Alison Tarke, Ph.D., North American winner of the @ItalyMFA_int “Science, She Says! Award!”
Tarke established important U.S.-Italy research collaborations amidst the COVID-19 pandemic https://t.co/mMiz5Uu58E
@aetarke@SetteLab@UniGenova#COVID19
New findings from @SetteLab, @Alba_Grifoni, and @aetarke!
🔎T cells against alpha or beta common cold #coronaviruses tend to be cross-reactive
🔎These viruses have MANY similarities in epitope sequences
🔎T cells showed cross-reactivity in 89% of tests
https://t.co/MIH8TTk398
Go T cells! How can we be better prepared for upcoming coronaviruses? We focus on the T cell side of the question in a recent collaboration between me @settelab@ljiresearch and Richard Scheuermann @JCVenterInst published in @CellRepMed https://t.co/Q061b9E7ee
Recently graduated and interested in viral immunology? We have a full-time open position as a research tech @ljiresearch appy now! Ihttps://www.linkedin.com/jobs/view/3427081522
Our team is hiring!
We're looking for a research technician with interest in COVID-19 and other viral diseases. It's a great opportunity for a recent graduate or early career scientist! And lots of fun working with @SetteLab & @Alba_Grifoni 😄
👀 https://t.co/E1X6SgCeAo
We found limited cross-reactivity in the sarbeco CoV group (containing SARS2) in our samples collected before the SARS2 pandemic, suggesting that exposure may contribute to the ability of T cells to recognize phylogenetically similar viruses. 5/5
Can CD4+ T cells cross-recognize different coronaviruses (CoV), offering immune protection from potential future CoV pandemics? We explore this concept in our new study, just posted in pre-print. https://t.co/Ps16V9tJGm
@Alba_Grifoni@SetteLab 1/5
We found that T cells can recognize different viruses when the coronavirus sequences were conserved. Specifically, if conservation was >67%, we observed cross-reactivity in 89% of the fragments tested. 4/5