Angela Goncalves

Computational biology group leader @DKFZ. Likes data, machine learning, stats, single-cells and aging-resistant species.

[Science and Innovation at Cancer Research UK @CRUKresearch]

Announcing the next phase of ACED, the International Alliance for Cancer Early Detection! 🎉

We are thrilled to welcome @DanaFarber and @DKFZ to our growing research community.

They join our continuing partners, @OfficialUoM, @ucl, @OHSUKnight, and @Cambridge_Uni, in this one-of-a-kind strategic collaboration to revolutionise cancer early detection for real-world patient impact.

👉 Read more: https://t.co/9n8KtodN7Y

[DKFZ @DKFZ]

The @BayerFoundation's Early Excellence in Science Award 2024 in the category of Data Science goes to Ivana Winkler of the DKFZ. 👏 Winkler's work uncovered the unexpected effect of female reproductive capacity.
➡️ https://t.co/YHgErlacxr

[Camille Berthelot @camilleberthelot.bsky.social @CamLBerthelot]

Looking for a PhD position in 2025? 🧑‍🎓
Interested in endometriosis research? 🩸

We are looking for a computational candidate for the Pasteur-Paris University PhD program to join a fantastic international collab between my lab, @afilimon and L. Doridot!

Please RT!

[Michael Baumann, MD @_MichaelBaumann]

Indeed - what a party celebrating our 60th birthday! The DKFZ is its people!

[IRB Barcelona @IRBBarcelona]

🗣️The 41st #BarcelonaBioMed Conference reveals new avenues for #cancer prevention.

➕150 international scientists have discussed the factors that contribute to the risk of getting #cancer & their implication in the prevention of the disease.

🤝@FundacionBBVA

Read more here ➡️https://t.co/m2KlF0kTqP

[IRB Barcelona @IRBBarcelona]

🗣️Fully immersed in the #conference "Cancer Promotion: Understanding Cancer Promotion to Inform Prevention"!

🔝With leading experts sharing groundbreaking insights, this event is pivotal in advancing our understanding of #cancer.

A remarkable moment for collaboration and progress in #CancerResearch!

#BarcelonaBiomed

[Angela Goncalves @afilimon]

@michelle_c_ward Congrats Michelle!!

[Angela Goncalves @afilimon]

@GuezguezL Thank you so much Borhane!

[Angela Goncalves @afilimon]

You can explore the analyses of our #aging mouse #reproductive atlas through a Shiny app: https://t.co/LmeO0r2OeT It includes differential expression, TF activity, cell-cell communication and links to the raw data.

[Angela Goncalves @afilimon]

@NeBanovich Thank you Nick! super happy this is finally out :)

[DKFZ @DKFZ]

Scientists from DKFZ have uncovered unexpected long-term consequences of female reproductive function: The constant remodeling of the organs of the reproductive tract during the reproductive cycle leads to fibrosis and chronic inflammation over the years.
https://t.co/AP32BhcNDD

[Angela Goncalves @afilimon]

@tolkachov2112 @JasperPanten @FloGrunschlager @haas_lab @odom_lab @dfg_public Thank you also to @augustoschneide for the VCD model!

[Angela Goncalves @afilimon]

Happy to announce that our story on the effect of #aging and estrous cycling on the female #reproductive tract is out @CellCellPress https://t.co/ETvRxjkDIG It was a fantastic effort by Ivana Winkler @DKFZ. Follow the 🧵 to find out the unexpected cost of cyclical remodeling...

[Angela Goncalves @afilimon]

Thank you to @tolkachov2112, Fritjof Lammers, Perrine Lacour, Klaudija Daugeleite, @JasperPanten, @FloGrunschlager, @haas_lab and the @odom_lab, it's been a pleasure. Thank you to the @dfg_public for funding.

[Angela Goncalves @afilimon]

@marta_mele_m Thank you Marta!!

[Angela Goncalves @afilimon]

@mele_lab @DKFZ So glad our work is being used ❤️ the final revised version just came online with a lot more spatial data @CellCellPress: https://t.co/ETvRxjkDIG

[Angela Goncalves @afilimon]

Congrats to Klaudija Daugelaite, Perrine Lacour & Ivana Winkler! With the @odom_lab @dkfz

[Angela Goncalves @afilimon]

Why is the success rate of IVF so low? In our new study in mice we find that oocyte-granulosa intercellular communication is severely disrupted by the exogenous hormones used to trigger superovulation: https://t.co/bxqoIfMvkk

[Angela Goncalves @afilimon]

Superovulation causes the release of two classes of oocytes with distinct developmental potentials. These classes can be predicted with reasonable accuracy by non-invasively profiling the transcriptome of the associated granulosa cells.