AggarwalLab

Synthetic organic chemistry group focused on the incorporation, homologation and functionalisation of organoboron compounds. Group ran account.

[AggarwalLab @AggarwalLab]

We say goodbye to Max Roth, our visiting Master’s student from RWTH Aachen University 🇩🇪

Wishing you all the best in your future endeavours, Max!

[AggarwalLab @AggarwalLab]

Congrats to our very own Prof. Varinder Aggarwal who has been awarded the 2026 Nagoya Gold Medal Prize. This prize was established in 1995 by Prof. Noyori and is awarded to an organic chemist who has made significant original contributions to the field in its broadest sense.

[AggarwalLab @AggarwalLab]

Think outside the box, but for stubborn thiazoles, think outside the ring!

Our latest @angew_chem, (in collab w/ @merckgroup) LiBAP cross-coupling, exploits an out-of-ring sulfinyl activation unlocking 1,2-migration that thiazoles resist.
https://t.co/bHq0PfmxeW
@BristolChem

[AggarwalLab @AggarwalLab]

One catalyst, two geometries.

Check out the work from the Zheng and You group showing how Ir catalysis enables stereodivergent access to chiral Z- and E-allylated isochromanones.

Original article: https://t.co/KfD3BCEZlZ

Our Preview: https://t.co/F8WWCfOmzR

[AggarwalLab @AggarwalLab]

Rule breaking continues!

Our latest work with the Paton Lab @bobbypaton shows how tuning electronics controls [2+2] photocycloaddition regioselectivity, enabling selective access to distinct aza-bicycles.

https://t.co/6vTQalEN4n

#Photochemistry @BristolChem

[AggarwalLab @AggarwalLab]

Forget airbending. We’re ozone-bending. 🌬️

Our latest @J_A_C_S paper on dealkenylative borylation combined ozonolysis and Fe cat to shorten the synthesis of the a pheromone from 11 (lit.) to just 2!

Congrats team! 🎉
https://t.co/jun8lUi8kI
@BristolChem #Organoboron

[AggarwalLab @AggarwalLab]

We say goodbye to Suguru (@RGS_202803), our visiting researcher from the University of Tokyo. 🇯🇵

Wishing you all the best as you head back to Japan to finish your PhD. Thanks for being part of the Aggarwal Lab, and best of luck with the final stretch!

[AggarwalLab @AggarwalLab]

Prostacyclin just got an upgrade!

Excited to share our latest work with the @HersIngeborg group, now out in J. Med. Chem. (@ACSBioMed). Our chemically stable PGI₂ analogue is the most potent reported to date. Congrats team! 🎉

https://t.co/FOX1itLRQe

@BristolChem

[AggarwalLab @AggarwalLab]

Finally, electrophilic amine joins the migration club. 🎉

Check out our latest @NatureChemistry paper on amination-induced 1,2-boronate migration, enabling direct access to unprotected β-amino boronic esters. Congrats team!

https://t.co/PtU7EbHZda

#organoboron

[AggarwalLab @AggarwalLab]

Radically sweet indeed! 🍬 Chuffed to see Our collaboration with the @BaranLabReads reaching @Nature. Congratulations to everyone who made this possible! 🎉

@BristolUni @BristolChem

[Baran Lab @BaranLabReads]

Appearing today as an Accelerated Article Preview publication in @Nature :https://t.co/uWKIj77IR7

[Baran Lab @BaranLabReads]

Appearing today as an Accelerated Article Preview publication in @Nature :https://t.co/uWKIj77IR7

[AggarwalLab @AggarwalLab]

Check out SYNFACTS’ (@thiemechemistry) Highlights in Chemical Synthesis featuring Hanwen and Roucheng’s JACS paper on Ni/PRC-enabled C(sp³)–C(sp³) deboronative and decarboxylative coupling:

https://t.co/VXGNpo8D9U

https://t.co/rf1HXDopsr

[AggarwalLab @AggarwalLab]

We would also like to say goodbye to Denisa, who is returning to the Czech Republic to finish her PhD. We hope you enjoyed your research visit in our group. All the best, Denisa! 🎉

[AggarwalLab @AggarwalLab]

Today, we are *simultaneously* (pun intended; cf. JACS 2024, 146, 13719–13726) sad and delighted as Dr. Shen wraps up his time in our group. Sad to lose a postdoc powerhouse, but thrilled to see him kick off his independent career back in China. All the best, Hong Cheng! 🎉

[AggarwalLab @AggarwalLab]

Avengers! Assemble... alkyl phosphonates.

Check out our new @angew_chem paper for the direct C(sp3)–H phosphonylation of unactivated alkanes ⚗️ Using an iron photocatalyst.

Congrats Team!

https://t.co/dmiEk1bC1t
@BristolChem #photocatalysis

[AggarwalLab @AggarwalLab]

Our latest work with @duarte_group shows the unexpected exo-C2 lithiation of ABP and ABH, allowing access to ring-opening products with full stereocontrol.

Congrats Team!

#OrganicChemistry #StrainRelease @BristolChem

https://t.co/ifzhserezI

[AggarwalLab @AggarwalLab]

🎉 Chuffed to see our JACS paper is among the most read articles this month!

See how a boron-mediated Ni/photoredox strategy for hydroalkylation of olefins enabled the access to quaternary carbons.

https://t.co/rf1HXDopsr

Congrats Team!

#Photoredox #Organoborons @BristolChem

[AggarwalLab @AggarwalLab]

Mixed emotions… 😊 Proud that Dr. Liang Wei is starting his independent career at Huazhong University of Science and Technology 🇨🇳✨, but sad to say goodbye to one of the kindest and brightest postdocs in the Aggarwal Lab.

All the best, Liang! 🚀

[AggarwalLab @AggarwalLab]

Au revoir, auf Wiedersehen, arrivederci! 👋

Time flies✈️,our three visiting researchers are now back to their home universities to continue their research journeys.

All the best to @GrossAdrien5 (🇫🇷 → Uni Freiburg 🇩🇪), Fin (Uni Hannover 🇩🇪), and Federica (Uni Pavia 🇮🇹)!

[AggarwalLab @AggarwalLab]

Breaking the rule-of-five in [2+2] cycloadditions!⚡

Check out our @NatureSynthesis article where a radical stabilization strategy enabled Photo EnT route to elusive 3D-isosteres of 6 membered N-heterocycles.
https://t.co/lTta55UNi3

#Photocatalysis #bioisosteres @BristolChem