Congrats to @nicoleleejw (and other @ConfinementLab co-authors) on her main story coming out this month in @CellReports! Check out this thread if you’re interested in what Nicole discovered on the role #MechanicalMemory plays in facilitating cell migration in #confinement
@nicoleleejw is defending her #PhD in a few weeks and will be on the #postdoc market, so get in touch with her if you are looking for an outstanding #mechanobiologist!
Congrats to @nicoleleejw (and other @ConfinementLab co-authors) on her main story coming out this month in @CellReports! Check out this thread if you’re interested in what Nicole discovered on the role #MechanicalMemory plays in facilitating cell migration in #confinement
Also, since it didn't get selected but I really like the design from @ConfinementLab's Jennifer Marlena, here's our cover art! Bonus points if you can guess my favorite artist... #destijl
Huge congratulations to our Microfab MacGyver Gianluca Grenci for his new position at @UniPadova! As a result-@MBIsg is on the hunt for a new Microfab core facility head. Feel free to get in touch with me or Gianluca with questions! https://t.co/lsGvj8U67n
First international @ConfinementLab retreat on the tropical island of Langkawi (aka Lab-kawi) is in the books! There was plenty to explore for the #beachcrew, #junglecrew, and #culturecrew! Want to join in on the fun as a PhD student or postdoc? Get in touch!
Congratulations to newly minted Dr. @LY_Sci, Ph.D. #3 from the @ConfinementLab, aka Dr. Kueh Auntie, for her successful defense! If you're wondering what #Kueh has to do with confinement, keep an eye out for Yixuan's upcoming paper!
Attention #undergrads! Interested in experiencing a summer of #mechanobiology research at @MBIsg ? Apply for our MUST program! We accept students from all around the world, so don't hesitate to reach out for more information!
@jess_kabigting@Yusuke_Toyama@ahcells showed us the challenges of how immune cells are able to digest and clear large adipocytes (~100um) often found in aged tissue. Multiple smaller macrophages need to infiltrate an ECM shell to reach the dead adipocytes! #MBIMPG2025
How do cells remember their mechanical environment? Nicole Lee @ahcells@MBIsg identifies transcription factor NFATC2 as a key regulator of mechanical memory – a link between past stiffness and future behaviour such as enhanced migration through confined spaces. #MBIMPG2025
Day 1, done and dusted! But the party is just getting started with The Hawker Center Mentorship Night at three of Singapore’s most iconic hawker centers – ABC Brickworks, Lau Pa Sat and Newton Food Center. See you there! #MBIMPG2025
Big picture, we think that interfering with this mechanism to attenuate or even prevent cancer cell #migration in tight spaces holds translational potential. Another example of #confinement helping us gain a better understanding of cell biology in general!