Postdoctoral Fellow @UAlberta_MMI working at the interface of Med Chem, virology, CADD and ChemBio. PhD in Organic and Medicinal Chemistry @TheWestGroup1.
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
The Suzuki reaction is named after chemist Akira Suzuki, who was awarded the chemistry prize in 2010. Chemists use Suzuki couplings to join carbon atoms together – they have been used to create polymers that emit light and to develop light-capturing molecules.
Chemistry that forms an omnipresent type of carbon–carbon bond enables the modular synthesis of 3D organic molecules — a boon for drug discovery and materials design
https://t.co/IRwCJifK8y
Dr. David Marchant presented at the World RSV forum in Rome. His team work on how a single mutation in the virus surface protein can change whether vaccines and antibodies can block infection. See more here:
https://t.co/IyuAuOKweJ
Final version. Congrats to Adam and Yujun! Thanks to the collaboration with the @YangjianQUAN group! Electrochemical defluorinative Matteson-type homologation @Nature @Boron_Chemistry https://t.co/F9jX4Ra7i0
The U of A now houses one of only five cryo-electron microscopes in Canada, revealing life’s smallest details at the atomic scale.
Funded by the Government of Alberta through SPP-ARC, the new facility will accelerate treatments for infectious and neurodegenerative diseases and cancer. https://t.co/FQEqNLmrBI
🦠A new article in @Nature_NPJ npj Viruses describes a single RSV-F mutation (L305I) reshapes the antigenic landscape, enabling RSV to evade neutralizing antibodies, despite the site being distant from epitopes.
https://t.co/bUcw7w4fCI
We characterized the catalytic properties, substrate scope and structure of KslB, an unusual Pictet-Spenglerase with the ability to form 1,1-disubstituted tetrahydrocarbolines: https://t.co/LwXeS0SOCb
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075 | Journal of Medicinal Chemistry - hot off the press. This drug will enter phase 2 clinical trials in 2025. https://t.co/1g8ze42E7D
A reminder on why you get higher hit rates from screening small molecules versus large ones.
A one thousand member fragment library covers relative chemical space ten million times more than a one million member HTS library.
⚠️ BREAKING:
Deadly Marburg Virus That Kills 9 Has Spread to Belgium, Hospital Visits Banned Following Deaths
A major outbreak of the 'eye-bleeding disease' Marburg has potentially reached Europe, with experts warning it could spread globally.
Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!
https://t.co/cxHl1j20CJ
🚨Job alert🚨Thrilled to share that the Gabr Lab received FIVE R01 grants for small molecule immunomodulators research. We are hiring postdocs with expertise in medicinal chemistry, neuropharmacology, or protein biochemistry. Applicants can send CVs to [email protected]
Excited to share our newest strategy to access carbenes from aldehydes - now via radicals!
Young & Jake found this highly practical, efficient, & selective way to make triangles - that even works in the presence of air or water!
@J_A_C_S
https://t.co/l57mWvRQIx