Aleksi Isomursu

Postdoc @etiennemannevil lab @institutpasteur 🇨🇵🔬 | Previously @IvaskaLab 🇫🇮 | Cell migration, mechanobiology, cancer | 🦋➡️

[epithelial mechanics fan club @EpiMechFC]

How is metabolism interconnected with cellular dynamics? We are @EManiou and @hpscenthusiast and through an energy inexpensive process, we will highlight advances in mechano-metabolism and related fields🧵@epimechfc

[Kumar Lab, UC Berkeley @kumarlabucb]

New paper in Advanced Materials! We develop a family of 3D viscoelastic HA matrices and use them to study effects of stress relaxation on GBM invasion. Led by @EmilyCarvalhoGQ in collaboration with Andreas Stahl and @ManishKAghi https://t.co/lglE66qAkt

[Wickstrom-Lab @WickstromLab]

Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress https://t.co/ijdKjiwHXl tweetorial👇

[Sirio Dupont @SirioDupont]

🚨 Super psyched this story is finally out!

Herculean effort and 3rd chef d’oeuvre in @NatCellBio by @patriziaromani in just 5y, where we describe #mitochondrial #mechanotransduction.

https://t.co/l9oRSFdhaH

Megathread with bonuses ⬇︎⬇︎⬇︎

[Johanna Ivaska @johannaivaska]

Super excited about this amazing collaboration with @IvaskaLab @guijacquemet @SalmiLab and the https://t.co/j0QsWX8FbS lab https://t.co/cWBpD2yaqo
Identifying details of cancer cell and leukocyte adhesion to endothelial monolayer under flow

[THERY Manuel @ManuelTHERY]

Anna Akhmanova and myself wrote a comment for @CurrentBiology about this publication. We put it back into the context of previous works, summarized the most convincing parts and pointed at exciting questions about MT dynamics and cell migration.
https://t.co/p3mO501z1t

[Gray Camp @GrayCampLab]

Exciting new inroads into human biology and therapy development: Human intestinal organoids with an autologous tissue-resident immune compartment! #Gjorevski #Cabon #IHB @Nature @IHB_Research https://t.co/x6YWSjl8yp

[Xavier Trepat @XavierTrepat]

Looking for a summer read?🏖️🌞📄 You're in luck 😂. Our paper on optogenetic leader cells is out @NaturePhysics. We found a force-velocity relation for collective cell migration. Experiments by @LeoneRossetti, theory by @ricardalert. @IBECBarcelona
https://t.co/eAxUVIDs5P

[Sylvain GABRIELE @GabrieleSylvain]

📢 Do cells migrating on a confined environment have a mechanical memory of their previous state ? We tried to answer this question in our new preprint 👇🏼
https://t.co/UZPyg5fhrB
an outstanding work by @KYohalie and very great collab with @d_brueckner

[David Brückner @d_brueckner]

How do cell interactions determine the migration of cell trains? 🦠🚂🤔

Check out our latest study in @NaturePhysics in collab w/ @GabrieleSylvain @EdouardHannezo @XavierTrepat & experiments led by @EleonoreVercru!

➡️https://t.co/ijKlg3eTyN

[THERY Manuel @ManuelTHERY]

I have been fooled by such images. They very much suggest that the balance of pulling forces along microtubules center the array.
...

[Xavier Trepat @XavierTrepat]

Some of us were asked by @CellCellPress about the future of mechanobiology. In all likelihood, 20 years from now we'll see we were all wrong. Any thoughts? What did we miss?🤔🔮👇https://t.co/TW1AN6QIkf

[Oded Rechavi @OdedRechavi]

A super important paper from Giacomo Cavalli's group on epigenetic origins of cancer: Reversible depletion of Polycomb induces cancer in the absence of driver mutations
https://t.co/Uk49MDg7d5

[Johanna Ivaska @johannaivaska]

Fresh @Ivaskalab review on #MechanoBiology and #Migration with @MathildeMthu @aisomursu Positive and negative durotaxis – mechanisms and emerging concepts https://t.co/NIoNMYsf5v

[Michal Dibus @DibusMichal]

Excited to share that our mini-review highlighting novel tools in adhesion research has been published in Current Opinion in Cell Biology!
@Omkar_Joshi_ @IvaskaLab

https://t.co/MXpbxNoWhv

[Aleksi Isomursu @aisomursu]

@sujanghm Thank you Sujan!

[Aleksi Isomursu @aisomursu]

Concluded one chapter yesterday. 🎩 Big thanks to Vinay @LabSwaminathan for being such an amazing opponent!

[Ivaska Lab @IvaskaLab]

This is an awesome wk for the lab! ERC adv grant for the lab, followed by @aisomursu PhD defence! Congrtulations Aleksi and @johannaivaska on the PhD success. A huge thanks to Vinay @LabSwaminathan for being here today as Aleksi's opponent and for the exciting discussion!

[Johanna Ivaska @johannaivaska]

@IvaskaLab offered the @ERC_Research AdG! Excited to pursue #BorderControl to gain fundamental understanding of metastasis in collab with @guijacquemet @EPeuhu @ValerioIzzi @PekkaRuusuvuori @BioscienceTurku @InFLAMES_Health @UniTurku @pipsa_saharinen @WickstromLab @SalmiLab

[Aleksi Isomursu @aisomursu]

@sarahdezperez Of course, I'll keep you posted. 👍