Alex Wang

Scientist @gensaic @labcentral working on gene therapy, previously liver engineer @MITBE

[Alex Wang @ajwang3]

@JuanGnecco4 @LindaGGriffith1 Congratulations on a great paper!

[Alex Wang @ajwang3]

Since I had photo duty today...for anyone interested in both running and talking biotech, join the @atlasventure hosted runs every Thursday at 7am in Tech Square! #RunningAtlas

[gensaic @GensaicBio]

Catch our team at #ASGCT23! We’re looking forward to learning and discussing the newest developments in gene therapy.

[Alex Wang @ajwang3]

Gensaic is now using our platform to develop a gene therapy for CF! In related news, I'll be the lead for our internal CF program, so please let me know if anyone wants to talk about gene therapies for CF and the lung.

[gensaic @GensaicBio]

Gensaic has received funding from the @CF_Foundation to help us develop our gene therapy platform for CF! We are highly appreciative and excited about this opportunity to work on this severe disease.
https://t.co/pCrk8wWlKN

[gensaic @GensaicBio]

Gensaic has received funding from the @CF_Foundation to help us develop our gene therapy platform for CF! We are highly appreciative and excited about this opportunity to work on this severe disease.
https://t.co/pCrk8wWlKN

[Cystic Fibrosis Foundation @CF_Foundation]

We are investing up to $3.5M in Gensaic Inc. to conduct preclinical research to develop a new approach to deliver a gene therapy to the lung cells of people with #cysticfibrosis.
https://t.co/Er8ivtdAm3

[Alex Wang @ajwang3]

Great work by @jyhsu15 and team!

[LabCentral @LabCentral]

And the results are in! Congratulations to @futurefieldsHQ and @GensaicBio on securing this year’s @novonordisk Golden Ticket! #WhereBiotechBegins

[Alex Wang @ajwang3]

Excited to share a new collaboration between
@GensaicBio and @OvidRx to help develop our gene therapy platform for CNS indications:
https://t.co/uvytmxzahU
Fun times ahead!

[Alex Wang @ajwang3]

Exciting new paper demonstrating the possibilities of the gensaic phage-derived particle (PDP) platform:

[gensaic @GensaicBio]

Our co-founder Amin Hajitou just published a paper using engineered phage-derived particles (PDPs) for cancer immunotherapy: https://t.co/x6tzuEKcMM .../

[snicobio @snicobio]

Silent mutations aren't so silent. Interesting study showing that amino acid correction with synonymous codons doesn't restore protein function. Possible explanations: distortion of mRNA structure, altered half-life, and/or low abundance of the cognate tRNA

$BEAM

[Alex Wang @ajwang3]

We're hiring a research associate @GensaicBio! Come join our team of phage gene therapists: https://t.co/JCfXOh19RU
#STEMcareers, #genetherapy

[Alex Wang @ajwang3]

Excited to announce M13 Therapeutics is now gensaic! Our new name (gene + mosaic) reflects our vision of building a nonviral genomics medicine platform company.

[gensaic @GensaicBio]

Officially launching our new name and website: https://t.co/b1GdeDwjuw

[Alex Wang @ajwang3]

@TIlyaich Interesting tech, but probably has limited application in its current form. NHP data shows the need to 3x dose ImmTOR just to not see antibodies at day 84. A single dose still led to AAV-8 abs after day 56! Hard to say if this can be tolerated for human AAV redosing...

[Alex Wang @ajwang3]

Some of my takeaways from #ASGCT22 after taking the weekend to digest. (From someone relatively new to the gene therapy field)…/

[Alex Wang @ajwang3]

7) Conclusion: There has been amazing progress in the science and engineering of gene and cell therapy. There are still a lot of challenges, but the creativity of academics and industry researchers are rapidly paving the way for exciting and novel medicines.

[Alex Wang @ajwang3]

6) I'm not as well-versed in cell therapies, but that is a whole other mind-blowing side of ASGCT I'm planning to delve more into in the future. Excited to see the potential of engineered iPSCs, T-cells, NK cells, macrophages, and bioprinted organs for therapeutic applications...