Alam Leon

Q.F.I. Maestro en Farmacología, Escuela Superior de Medicina (ESM), Instituto Politécnico Nacional (IPN)

Pues... a trabajar

[Kyle Tretina, Ph.D. @AllThingsApx]

🏭AlphaDesign just turned AlphaFold into a programmable protein‑design factory:

Hallucinate a backbone, diffuse the sequence, and ship it; no model retrain is needed.

Monomers, oligomers, bispecifics, shape‑shifters, 17 / 88 hits active in vivo 👀

[Tamayo @Tamayo_Mtz_JP]

Hi @LatinXChem community, I present my work related to Bioinformatic design of molecules with dual PPARg/PTP1B activity as potential antihyperglycemic effects.. #LatinXChem23 #LatinXChemBio #Bio061 @rsc_chembio, @ChemBioChem @humefigueroa

[Alam Leon @AlamLeon1]

@Varolete Felicidades!!

[Alam Leon @AlamLeon1]

@JaSantaolalla Le falta el bolillo para el susto y llegar 3 horas tarde a una fiesta Dr.

[Alam Leon @AlamLeon1]

@danyesva_ Vale, está hermoso ese diálogo!!, lo intentaré leer

[Guild Wars 2 ES @GuildWars2_ES]

Os presentamos al espectro, la nueva especialización de élite del ladrón que llegará con #GW2EOD. https://t.co/tacwUPoVO5

[IPN @IPN_MX]

#ComunicadoIPN 🗒️ Se unen IPN y Huawei para impulsar nuevos talentos

Más información ➡️ https://t.co/9R1tCXqFtu

[Laurent Vial @lo_vial]

You know it's true

[IPN @IPN_MX]

Con un minuto de silencio en honor a los 256 politécnicos fallecidos por #COVID19, el Director General del IPN, Arturo Reyes Sandoval, dio inicio a la Tercera Sesión Ordinaria del XXXIX Consejo General Consultivo.

[IPN @IPN_MX]

#ComunicadoIPN 🗒️ Prevención y ciencia de frontera, elementos importantes contra el cáncer: científico del IPN

Más información ➡️ https://t.co/QZqxThLPR5

[David S. Goodsell 🏳️‍🌈 @dsgoodsell]

Fixed up the errant ribosome and brightened up the colors on the "SARS-CoV-2 Fusion" painting for "New Ways of Living," a show for SciCommMake. A full size file and key is @buildmodels at https://t.co/v76XpcGyFc . #cellspace @SigmaXiSociety @ScienceTalkOrg

[Humberto L Mendoza Figueroa @humefigueroa]

Doctorado en Nanociencias - IPN, Convocatoria Feb-Jul 2021.

[LatinXChem @LatinXChem]

#LatinXChem in the news!

https://t.co/Nl2RYbiTre

[Angelica Flores López @Angelic92394430]

Hola @LatinXChem , este es mi trabajo " WAPAL TAIXNEXTIKA TATAMAN OKSEPATIS NESKAYOT Del Español al Náhuatl:  Adaptación de la Tabla Periódica al Náhuatl”, #LatinXChem #LatinXChemEd #Ed17 @ITSZACAPOAXTLA

[Viviana Morales @viviamorales]

Hola a todos @LatinXChem, este mi trabajo “aprovechamiento de residuos agroindustriales como nuevos materiales para la obtención de bio-nanocompositos para uso potencial en envase alimentario” #LatinXChem #LatinXChemAnalytical #AC34

[rany 🌟 @danyesva_]

Hi @LatinXChem, this is my work “Aplicación de Lipasas de Candida rugosa como biocatalizador enantioselectivo para la resolución Cinética de (S)-Ketoprofeno”, #LatinXChemCat Cat72

[Alam Leon @AlamLeon1]

@BarbosaBarretto @LatinXChem @ESM_Oficial @IPN_MX Cardiopathy*

[Alam Leon @AlamLeon1]

Hi @LatinXChem, I share my research work "Bioinformatic approach to the design and development of drugs with hypoglycemic and anti-neuropathic activity", which is developed in @ESM_Oficial of @IPN_MX 🇲🇽 #LatinXChemBio BIO-18 #BIO018
⬇️
Support information:https://t.co/fDoYCyPtLu

[Alam Leon @AlamLeon1]

@BarbosaBarretto @LatinXChem @ESM_Oficial @IPN_MX Rosiglitazone activates PPAR alpha receptors, which cause heart disease, our design focuses on selective PPAR gamma agonists. Additionally, the hydantoin nucleus has been shown to be better tolerated in liver metabolism.
https://t.co/28P6nIe760

[Alam Leon @AlamLeon1]

@Mod_Molecular @LatinXChem @ESM_Oficial @IPN_MX The design is based on structural fragments, it was found that both PPAR gamma agonists and AR inhibitors have a polar region that is demarcated by this type of heterocycles, and our results infer affinity in both targets and it is inferred that their toxic effects tare minors.