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"The AlphaFold advance was possible only because of the Protein Data Bank, a laboriously created database of protein structures that the National Science Foundation began funding in the 1970s. No Protein Data Bank, no AlphaFold."

https://t.co/xoFyzAJPV8

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Molecular Origami: Build 3D Paper Models of Protein Domains
Download printable alpha helices and beta strand templates for hands-on exploration of protein folding domains, including a TIM Barrel and a Beta Sandwich
https://t.co/LezcZftIWB

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Computed Structure Models (CSMs) at RCSB PDB Updated from AlphaFold, ModelArchive
Updated CSMs include data from AlphaFold v6 and a refresh of files from the ModelArchive
https://t.co/7gXAPCe03H

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Molecule of the Month: Therapeutic Phage
Using the natural predators of bacteria to fight antibiotic-resistant infections
https://t.co/kF28Qgv6L8

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Researchers pioneer method to rapidly design proteins
Their strategy revealed new details that open the door to designing proteins with powerful abilities that could ultimately benefit medicine and manufacturing.
https://t.co/ExWSQVIGWG

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A nanosized extract of the plant thylakoid grana — the molecular engine behind photosynthesis — is transplanted into the eye’s corneal cells, producing a key protective molecule when exposed to ambient light, opening a new front against dry eye disease
https://t.co/MXHscq5U5i

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Join the RCSB PDB DevOps Team at Rutgers
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Impact of PDB Structures on Anti-Cancer Drug Approvals:
Open access to PDB data facilitates discovery and development of life saving drugs
Full flyer at https://t.co/nd8UN8pTgJ
#NationalCancerResearchMonth

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Video: Immunology and Cancer
Visit PDB-101 to watch a three-part series exploring the cellular and molecular details of the human immune response to cancer. Now available in English and Spanish #NationalCancerResearchMonth
https://t.co/vzGiL8hOIN

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Transglutaminases play essential roles in most of our cells, and also indispensable tools in food biotechnology. For example, a small bacterial transglutaminase helps improve the texture of hot dogs and other meat products #HappyMemorialDayWeekend
https://t.co/rVVIPpx4q4

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Improving vaccine design for Ebola, HIV and more
Scripps Research scientists and colleagues develop a nanodisc platform that offers a clearer view of how key viral proteins interact with antibodies.
https://t.co/bGURpnwleh

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Inflammatory and Autoimmune Disease Therapeutics Informed by Tick Protein
https://t.co/1tjLcaaapV

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PROTACs: A modular approach to protein destruction
More at Molecule of the Month: https://t.co/hf5yVPlLDa

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May is National Pet Month.
Cats Iris (tortoise) and Ares (grey) help RCSB PDB's Ezra Peisach manage the PDBx/mmCIF Dictionary and preparations for the upcoming transition to extended PDB IDs and the new Beta Archive https://t.co/6Ud3bbQTDU

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Contact Customer Services with Questions and Feedback
RCSB PDB collects and answers questions about the website, PDB data, and structural biology. A new chatbot answers general questions about structure deposition, biocuration, and more.
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RCSB PDB will discontinue rsync protocol for PDB Versioned and NextGen archives starting June 22, 2026. Users are encouraged to use rsync at PDBj or the https protocol for these archives.
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The genome of ebola virus contains instructions for building seven proteins, which assemble with the genomic RNA to form one of the deadliest viruses. More at PDB-101: https://t.co/j4nwGiefRZ

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First-in-class molecules block a specific protein interaction in immune cells, offering a potential targeted approach to autoimmune diseases like lupus and rheumatoid arthritis.
https://t.co/QgWqiaUYc1

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Try this new online training game from Leandro F. Estrozi designed for newcomers in structural biology, with a focus on cryo-EM and cryo-ET map interpretation: https://t.co/gxhQXmRPWL