Alekhya Amudalapalli

MD, DM Clinical Immumology Rheumatology

[Prakashini @prakashini_]

It’s imperative everyone learns Adlerian psychology as early as possible in life!

Truly thought-provoking and life-changing

Thank you @kishimi @fumiken for making it so lucid!

#reads

[Roxana González @RoxOsler]

Repeat kidney biopsy in lupus nephritis?
🔹It distinguishes active inflammation from chronic damage.
🔹Only 44% of clinical remissions = histologic remission.
🔹Biopsy helps guide treatment decisions, including tapering.
🔹Biopsy-guided care = fewer flares. #LUPUS2025

[Alekhya Amudalapalli @alekhya_7]

@ancesmulles @rheumarhyme @APLAR_org @EMEUNET @eular_org Looking forward to it! @ancesmulles

[Alekhya Amudalapalli @alekhya_7]

@rheumarhyme @APLAR_org @ancesmulles @EMEUNET @eular_org Thank you @rheumarhyme

[ILLIASUL IBAD @IlliasulK]

Tweet 14 (Final Tweet):

🔬 Key Takeaways on Dactylitis:

✅ Not just tenosynovitis!
✅ Think functional entheses & accessory pulleys
✅ “Rope-on-fire” on USG & MRI for deeper insights
✅ Marker of PsA progression!

🔁 Retweet & share with fellow Rheumatologists, MSK Radiologists & Imaging Experts! 🚀

#Rheumatology #Dactylitis #PsA #Enthesitis #Ultrasound #MRI #MSKImaging

[Dr.Mukesh , MD , DM @dr_immuno29]

‼️Takayasu Arteritis & Spondyloarthritis: A Shared Immunopathology**

- **Historical Context**: 50 years ago, the overlap between seronegative spondyloarthropathies was controversial but recognized.
- **Inclusion of Takayasu Arteritis**: If more prevalent in the UK, TA would have been clinically included with spondyloarthropathies; now supported by shared immunopathology.
- **MHC-1-opathy**: Evidence shows a common immunopathology in spondyloarthropathies linked to CD8 T-cell dysregulation and the IL-23–IL-17 axis.
- **Overlapping Features**: TA shares clinical features with spondyloarthritis like aortic root inflammation, inflammatory bowel disease, and HLA-B*52 association.
- **Pathophysiological Distinction**: TA's hallmark is granulomatous inflammation, driven by type 1 cytokines (IFN, TNF) from IL-12.
- **Immunogenetics**: Both conditions linked to IL-12B, influencing IL-23 and IL-12, key in cytokine responses.
- **T-cell Plasticity**: Explains both the distinct and overlapping features between TA and spondyloarthritis, including similar responses to TNF inhibitors.
- **Therapeutic Implications**: Recognizing shared mechanisms suggests potential for unified T-cell targeting treatments across these diseases.

https://t.co/DIUY083ije

#MedTwitter #RheumTwitter #Sharedimmunopathology #TA #TakayasuArteritis #MHC1opathy

[Alekhya Amudalapalli @alekhya_7]

My family are victims of a scam at ongoing Kumbh Mela in Prayagraj, where fake accounts like this were used to fraudulently book tents in name of government. Requesting @UPGovt @myogiadityanath to take immediate action to stop such scams and protect devotees. @dgpup

[Danish Sait @DanishSait]

Only my life is boring or what? 😭

[Dr. John Cush @RheumNow]

Small but useful open label RCT of MMF vs CYC vs TAC in SLE nephritis

Surprisingly similar rates of remission at week 24... suggests TAC could be an option for induction?

#ACR24 @RheumNow Abstr#0670 https://t.co/dr3M3cnjRG

[liminal @Liminal1988]

I came across a quote that said:

[Alberto Giraldo @alb_giraldo]

2024 EULAR points to consider on the initiation of targeted therapies in patients with #inflammatory #arthritis and a history of #cancer

🔗https://t.co/iDoiTgVYJm

[Alekhya Amudalapalli @alekhya_7]

@prakashini_ @TedDanson @netflix

[ASAS @Official_ASAS]

💫 Check out the results of an ancillary analysis of the ASAS perSpA study examining prevalence of SpA patients with purely peripheral SpA.

👉 https://t.co/zKu8QKb6H7

#Spondyloarthritis #ASAS #ASASPerSpA

[Dr. John Cush @RheumNow]

Cyclophosphomide vs Mycophenolate vs Tacrolimus in Lupus Nephritis

Dr. Mike Putman discusses abstract 0670, presented at #ACR24.

https://t.co/aLzsSSOmML

[Alekhya Amudalapalli @alekhya_7]

@prakashini_ @RheumNow Thank you

[Guru Samy @WellSaidGuru]

Upma was served in a breakfast every morning in a hostel with a capacity of 100 people. Out of those 100 people, 80 people used to complain every day that different items should be made instead of upma.
But, the other 20 people were happy to eat upma. The remaining 80 people wanted to cook something other than upma.

The hostel warden voting method was proposed as some decision had to be reached in this chaotic situation.

According to this, whichever tiffin gets the most votes, that tiffin will be cooked that day.*

20 students who wanted Upma cast their vote accurately. The remaining 80 people cast their vote as follows.
18 - Masala Dosa
16 - Aloo Parotta & Dahi
14 - Roti & Subg
12 - Bread & Butter
10 - Noodles
10 - Idli Sambar

So, as per the voting results, Upma gets the highest number of votes, and again the same is served every day.

Lesson: As long as 80% of the population is selfish, divided and scattered, 20% will rule us.

This is a silent message.

[Ritasman Baisya @RitasmanB]

⚡Learn nail 💅 fold capillaroscopy
👉Non-scleroderma pattern - normal or nonspecific
👉Scleroderma -early, active, late
👉Density, dimension, morphology, hemorrhage
First 🥇track algorithm.
#ACR2024 #ACRAmbassador