#Breaking: New positive Phase III results demonstrate superiority of an investigational molecule over standard-of-care KRAS G12C inhibitors in the first global head-to-head study in KRAS G12C-mutant non-small cell lung cancer: https://t.co/Bsxy2BeZ51
New compound from @RevMedicines RM-055 disclosed at #AACR26
They took a subtle finding 👉🏽Daraxonrasib-CYPA complex modestly increasing RAS GTP hydrolysis 👉🏽 to build a RAS GAP on steroids. RM-055 flattens Daraxonrasib resistant tumors including RAS amplified cases across models.
Thank you to #MelMcLaughlin for speaking openly about her lung cancer, thankfully detected early & treated w surgery
Her story raises awareness of a widely misunderstood disease
Wishing Mel a smooth recovery & return on @Channel7 soon
https://t.co/PK6CPhGvuV
#LCSM#lungcancer
Akeso reports Phase III HARMONi-A trial positive for survival. Ivonescimab (PD1/VEGF bispecific) + chemotherapy vs chemo in #EGFR NSCLC post TKI already showed PFS benefit (7.1m vs 4.8m) but OS was in question. Full results to be presented at #WCLC25.
https://t.co/6GAlMA2K0N
In a single-center study of NSCLC resections (2008-2020), long-term postop mortality dropped by almost 50% (HR 0.59; 95% CI 0.45–0.78) over 12 years, despite stable early post-op complications, possibly reflecting multiple contributing factors
Read more: https://t.co/61CqiEGWbZ
https://t.co/T23XdWbItd
Hello all! After a great TOGA ASM I'm running the City2Surf to raise funds for Thoracic Cancer research. Thanks for all your support.
💡Starting out in thoracic oncology?
The @IASLC Communications Committee proudly brings you:
‘50 Years of Progress in NSCLC: A New Fellow’s Guide in the Clinic’
A whistlestop tour of key advances, distilled by global leaders
@JTOonline@OncoAlert#LCSM
https://t.co/aRjpaDYAbk
I loved watching "ER" when I was a resident. But I can't watch "The Pitt". It's too close to home. I take the care of self & colleagues much more seriously these days.
https://t.co/EoM2aCst87
Grateful for the opportunity to present DB-1311/BNT324 (a novel B7H3 ADC) a Ph 1/2 study in patients with heavily pretreated CRPC (Abstract #5015) at #ASCO25 🎤 @Macquarie_Uni investigators: John Park @DSabanathan@HowardGurney@AlisonZhangMBBS Wei Yen Chan 🧵 1/7
In a Review now published online, Fei Zhou, Haoyue Guo, Yang Xia, Xiuning Le, Daniel Tan, Suresh Ramalingam & Caicun Zhou provide a comprehensive overview of the treatment landscape for EGFR-mutant non-small-cell #lungcancer https://t.co/W7nT6149Za
Disheartening.
Frustrating.
Devastating.
Patients unable to access immunotherapy via PBS for recurrent NSCLC due to once in a lifetime rule that is inconsistent w/ current standard of care.
Communicating this to patients is hard.
@MOGA_ORG pls keep advocating for change 🙏
Surprising results, stereotactic radiation plus anti-PD1 for stage 1-2 NSCLC, addition of immunotherapy does not confer benefit #lcsm https://t.co/YrERyeBAco
🎙️ NEW PODCAST: Access to New Medicines: Which Surrogate Endpoints Matter?
Listen on Apple https://t.co/BXBiXqGSZh
Listen on Spotify https://t.co/6J6QQ7mfT4