Hepatosaurio

Música, Deportes y Medicina.

[Coskun Ozer Demirtas @drdemirtass]

🚀 The Baveno-HCC model is out!

We developed and validated Baveno-HCC, a novel, tumor-adjusted noninvasive model for predicting clinically significant portal hypertension (CSPH) in patients with hepatocellular carcinoma (HCC), now published in The American Journal of Gastroenterology (AJG).

💡 Why it matters: In patients with HCC, tumor burden can influence liver stiffness measurements (LSM) independently of portal pressure, potentially limiting the accuracy of Baveno VII criteria, particularly in patients with larger tumors (>5 cm).

📊 Key study takeaways:
• Cohort: 452 patients with paired LSM and HVPG measurements across six international centers.
• Model parameters: LSM, platelet count, spleen size, and tumor burden.
• Impact: Substantially improved rule-in performance in patients with larger tumors while maintaining high rule-out performance in both derivation and validation cohorts.

🧮 Try the online calculator: https://t.co/WcZIBvDkBL

📄 Read the full article: https://t.co/k1H7A2aIHS

Huge thanks to all our co-authors and collaborating centers for making this study possible!
@CatherineMezza1 Riccardo Sartoris @RautouE Mario Romero Cristóbal Rafael Bañares @sutac_cosmina @bogdanprocopet @allaire_manon Dominique Thabut Elba Llop Herrera Juan Carlos Garcia-Pagan @MuthuRajakannu @Eric_Vibert Tamar Taddei @ggarciatsao

@AmCollegeGastro @JasmohanBajaj
#BavenoHCC #Hepatology #HCC #PortalHypertension #LiverCancer #Elastography #AJG

[Arndt Vogel @ArndtVogel]

🔥off the press🔥
Pre-Liver Transplant Immunotherapy and Post-Transplant Outcomes in HCC: Global LIFT-HCC-1 Study
https://t.co/EHOF2df8Sg
👉408 pts
👉Tumor burden & AFP at LT associated with HCC recurrence
👉Rejection associated with non-HBV, irAEs, age, shorter ICI washout
🧐pre-LT ICI feasible, clinical utility needs to be established
@myESMO @EASLnews @ILCAnews

[Hepatosaurio @alextd92]

@El_pinche_norte … ponerles un lugar específico para eso. Es simple: la calle se hizo para el tránsito vesicular, no para poner un tianguis.

[Hepatosaurio @alextd92]

@El_pinche_norte Me parece incorrecto. Hay un mercado que me caga que se pone en Av. Nuevo México. Este mercado afecta la salida todos los jueves de las familias que vivimos ahí. Que cool que la gente se esfuerce y salga adelante vendiendo múltiples cosas, pero está mal. Creo que el gobierno debe

[☁️ @gardenofcolours]

colours of the sky

[Javier Crespo @DrJavierCrespo]

LITMUS in The Lancet
https://t.co/igj3goCDGN
👉 Non-invasive biomarkers can identify advanced fibrosis and cirrhosis with high diagnostic accuracy, but important limitations remain in diagnosing MASH and replacing liver biopsy.

[Sunil Taneja @drsuniltaneja]

Acute Autoimmune Hepatitis
🔵Recognize early, treat & identify patients at risk of liver failure before the window for effective therapy is lost.@ajay_duseja @RoyAHep @RohitMehtaniDM @drnipunverma @doc_arka
https://t.co/4V7I6hQbAN

[Showboi Walpaper @showboi_237]

Live wallpaper

[Unique Wallpaper @just_unique0]

Gradient live wallpaper

[Thomas Reiberger @ReibergerThomas]

#LiverX
🔑 take aways from @BavenoCoop VIII
https://t.co/glxmxFgQVb

[Joaquín Rodríguez | 🔎Endoscopia digestiva @joakirodriguez]

👁️ Qué describes todos los días en una gastroscopia 👁️?

GASTRITIS CRÓNICA.

Te doy varias sugerencias que pueden mejorar tus descripciones y tus informes por supuesto.

Vamos a graduar endoscópicamente la gastritis.

Si te apetece, aquí las tienes:

[Jan Král @KralJan]

⚠️ Key message from #UEGWeek2026: TIPS at the right time can be lifesaving. 🩸

From pre-emptive TIPS in high-risk patients to rescue TIPS and secondary prophylaxis.

✅ Timing and patient selection are key.

@my_UEG @LiverFellow #MedTwitter #PortalHypertension #Endoscopy

[Keith Siau @drkeithsiau]

Gastric intestinal metaplasia (GIM) - pearls from #UEGWeek 💡

1. Differentiate autoimmune vs H pylori and biopsy using Sydney protocol
2. Risk stratify based on MAPS3 guidelines
3. Use OLGIM staging for extent
4. For autoimmune gastritis, consider immunology, biochemistry and 3 yearly surveillance

[José Siles | AI | Data @josesilesdata]

Las MEJORES Herramientas de IA.

Separadas por categorías 👇

[ZGutier @ZGuti_]

Si vas a empezar una Serie de tv, NUNCA elijas:

❌ Pierdes tiempo

・Peaky Blinders 🇬🇧 (estética, cero guion)
・Sons of Anarchy 🇺🇸 (telenovela motera)
・The Boys 🇺🇸 (gore barato)
・Casa de Papel 🇪🇸 (trampas absurdas)
・Juego de Tronos 🇺🇸 (el peor final)

✅ 6 Joyas PERFECTAS ↓

[Frontline Gastro @FrontGastro_BMJ]

📰 New in Frontline Gastroenterology: a visual guide to immunotherapy in hepatocellular carcinoma

How does HCC evade the immune system, and where do checkpoint inhibitors act? This figure maps the immunosuppressive tumour microenvironment and the main drug targets.

🔑 Key points:
🧬 HCC cells overexpress PD-L1, downregulate MHC-I and secrete IL-10, TGF-β and VEGF
🛑 Tregs use CTLA-4 to block T cell co-stimulation via B7
😴 Exhausted CD8+ T cells co-express PD-1, TIM-3 and LAG-3
💊 Drug classes: anti-PD-1 (nivolumab, pembrolizumab), anti-PD-L1 (atezolizumab, durvalumab), anti-CTLA-4 (ipilimumab, tremelimumab) and anti-VEGF(R) (bevacizumab, cabozantinib)

Read the full article here👇
🔗 https://t.co/b4vwJkTLEj

@BritSocGastro @dr_aditi_kumar @OTavabie @DrJMKennedy @DunnePdj @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @dtleiberman

[Frontline Gastro @FrontGastro_BMJ]

🩸 FIT-positive but no colorectal cancer: what's going on? Tee et al followed 1,056 symptomatic patients for 3 years. Higher FIT levels were linked to IBD, vascular disease, upper GI pathology and perianal disease. Only 52% had documented safety-netting.

Read the full paper here:
https://t.co/OEXWqtxRJH

@BritSocGastro @dr_aditi_kumar @OTavabie @DrJMKennedy @DunnePdj @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @dtleiberman

[Pulaski Wallpaper @Pulaxki]

New Drop!

[Liver Transplantation Journal (LTxJournal) @LTxJournal]

Is portal vein thrombosis more than a clot?

In CLEARED, PVT carried higher 30-day mortality despite lower MELD-Na. This editorial argues PVT reflects structural disease of the portal vein, which may explain why anticoagulation often disappoints.

https://t.co/QkJOiXD0FN

#LiverX