⭐ Up to one-third of patients with #IBD in remission have IBS-like symptoms. A new Rome Foundation–IOIBD consensus defines this phenotype and outlines diagnostic and treatment strategies: https://t.co/w2GcoHzyZq
We continue with our series. Next up is a session with APGNA on how to stand out as a fellowship candidate especially in competitive fields.
📆 Mar 29, 2026
🕕 11:00 AM CST
Register for this webinar:
https://t.co/4mfiAlXGxX
#GITwitter#MedTwitter
Many patients with cirrhosis or AH get cross-sectional imaging in the ED, with a lot of this imaging suggestive of "enteritis" or "colitis," with evidence of enteric/colonic wall thickening.
Many reflexively treat with cipro/flagyl, regardless of symptoms.
🛑
⤵️ (1/2)
Liver fibrosis is often silent until it's advanced. How can we screen for it without immediate imaging or biopsies?
Enter the FIB-4 Score.
A quick tutorial on the most useful non-invasive screening tool for liver disease (especially MASLD/NAFLD). 🧵👇 #LiverHealth#MedEd #PrimaryCare
What is FIB-4? It's a calculated score that estimates the degree of liver scarring.
The beauty is its simplicity. You only need 4 routine clinical values:
1️⃣ Age 2️⃣ AST (liver enzyme) 3️⃣ ALT (liver enzyme) 4️⃣ Platelet Count
No fancy labs required. 🩸
Think of FIB-4 as a Triage Tool, not a diagnostic cannon.
Its greatest strength is its "Negative Predictive Value." It is excellent at RULING OUT advanced fibrosis. It helps identify low-risk patients who don't need expensive referrals or specialized testing right now.
How to interpret the score (Standard ages 35-65):
🟢 < 1.30 (Low Risk): High probability of no advanced fibrosis. Re-assess in 2-3 years. 🟡 1.30 – 2.67 (Indeterminate): The "Grey Zone." Needs a second look (e.g., FibroScan). 🔴 > 2.67 (High Risk): Suggests advanced fibrosis/cirrhosis. Refer to Hepatology.
⚠️ Important Clinical Pearl:
Age is part of the formula. Older patients naturally score higher, leading to false positives.
For patients aged > 65, the "Low Risk" rule-out threshold is raised to < 2.0 (instead of 1.30). Don't over-refer your older patients!
Summary: ✅ FIB-4 uses routine labs to triage liver risk. ✅ Great at ruling OUT disease (<1.30). ✅ Adjust the cut-off for age >65 (<2.0). ✅ High scores need specialist workup.
Practical updates in Metabolic liver dz @AmCollegeGastro by expert & leader @KanwalFasiha
📋Nomenclature MASH, metALD & SLD are on a spectrum
📋Alochol use underreported for metALD
📋Resmitrom and Semaglutide for F2-3 MASH
📋GLP1-RAs role in MetALD?🧐
@BCMDeptMedicine
non-invasive detection of post-op #CD. What’s your go-to?
✅@AGA_CGH SR/MA
2 interesting points
▶️recurrence rate is highly-variable 21-98%! Why?
▶️IUS looks GREAT - but I have Q’s about this…..(see next tweet)
https://t.co/yOpEDLDvH2
Steroid tapering in UC: Is a 6-week steroid taper as effective as a 10-week taper in UC?
• ✅ 10-week taper (vs. 6-week taper inferior) → higher steroid-free remission at 6 months with comparable relapse rates and adverse effects
👉 Bottom line: 10-week taper works better.
❓How fast should we taper steroids in Ulcerative Colitis?
Longer taper (10 weeks) better than a shorter course (6 weeks)
- Balancing relapse vrs adverse effects
- Setting of 5-ASA + Thiopurine use
- Probably not applicable to advanced therapy
https://t.co/gCqnyk9Uvl
Day 2 of @AmCollegeGastro 2nd Year Fellows Course agenda is packed with high yield topics!
Starting off with a phenomenal talk by
@ebtapper breaking down “Portal Hypertension”
Some high-yield pearls:
⭐️Treat ascites to improve survival and quality of life ⭐️Sodium restriction alone often fails and worsens malnutrition ⭐️Diuretics work when dosed correctly and monitored ⭐️Build systems: paracentesis clinics reduce harm ⭐️HE is common, underrecognized, and treatable ⭐️Lactulose = induction dosing when admitted with HE, not just aiming for 2-3 BMs per day ⭐️Rifaximin reduces recurrence ⭐️TIPS works in the right patient: good kidneys, heart, bilirubin, minimal HE
When used wisely albumin can help patients with cirrhosis says the best meta-analysis on this in @HepCommJournal
https://t.co/wKMh5zoXHw
But these trials are small and misuse - SO COMMON - outside of trials is harmful. How to thread the needle?
A fasting-mimicking diet induced clinical response and remission significantly more than usual diet in open-label trial of patients with mild-moderate Crohn disease.
https://t.co/l6VaJMHaFA
The most common chronic liver disease worldwide, metabolic dysfunction–associated steatotic liver disease (MASLD) affects approximately 30% to 40% of the general adult population.
This Review summarizes the diagnosis, treatment, and prognosis of MASLD. https://t.co/cnge8XGwQ6
Accumulating evidence of aspirin as a potential onco-preventative agent in IBD patients. Prospective study needed to analyze if it’s truly helpful as we continue to add aging patients in the compounding prevalence bucket of IBD epidemiology https://t.co/8TcPyP5gmT
2025 Best GI papers @GuildConference
🎤Achalasia ⬆️s all-cause mortality (esoph cancer and aspiration)
🤢 prucalopride for gastroparesis in guide
🎯 ing seropositive for celiac diagnoses doubles diagnoses
🥑 Mediterranean diet helps IBS
#MedTwitter#GITwitter#audreycald#evande