People with schizophrenia are underrepresented in volunteer-based biobanks. A new UK Biobank study shows that those who do participate tend to have milder symptoms, lower polygenic risk scores, and lower rates of copy-number variants. https://t.co/LOMr3ksUeA
@MariosGeorgakis@NAKO_Studie In case anyone was wondering: genotypes are *planned* to be made available mid-2026... I just reached out to them about this.
Ein Team der #CharitéBerlin hat dutzend neue Genvarianten gefunden, die mit der seltenen Autoimmunerkrankung Myasthenia Gravis in Verbindung stehen und zur Entwicklung neuer Früherkennungsmethoden oder Arzneimittel beitragen können. Mehr über die Arbeit 👉https://t.co/KE5jLW3LS2
Excited to share our new Genome-wide meta-analysis of myasthenia gravis! The study identifies novel genetic loci and enhances prediction models. Read more: https://t.co/bfjF5gIKBc @aliceb3000#Genetics#MyastheniaGravis
Calling all emerging scientists - it’s time to send us an application! 😉😎 Lead your own #MaxPlanck Research Group w/ €2.7M in funding over 6 yrs, full independence & resources to hire staff. State-of-the-art infrastructure awaits you!🌟 Apply today➡️https://t.co/cHxPLyRj9x
Tools that predict the causal genes in GWAS loci are too complex! Many use XGBoost models with >45 features (i.e. L2G, Ei).
CALDERA achieves better performance despite using LASSO regression and only 12 features. This makes it much easier to understand why a gene was chosen.
🎬 Exciting News! 🌍 GAMIAN-Europe proudly presents a new video series as part of the Psych-STRATA @HorizonEU project.
Don't miss these multilingual interviews on personalised mental health research. 🧠💡
👉 Read more: #MentalHealth#Research#PsychSTRATA https://t.co/Mx8O7UvlmD @ProfBaune@evdeycken
We took another shot at prioritizing genes responsible for schizophrenia through novel methods based on the latest @PGCgenetics GWAS.
I had a great time working on this project and am proud of what came out of it.
New pre-print from the @PGCgenetics#Depression Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets.
🔗 https://t.co/eAh41d9XfA
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#Reminder: The €500k #EinsteinFoundationAward w/ @questbih aims to provide recognition & publicity for outstanding efforts that enhance the rigor, reliability, robustness & transparency of research in 3 categories. The #CallForEntries closes 30/04/2024: https://t.co/B4mwSX9IVP