Anand Lab

Integrative structural biology lab at Penn State University

[Anand Lab @anandlabpsu]

We’re excited to announce our latest paper in J. Mol. Biol. led by @victori84080201!! Using HDX–MS, she uncovered how acidic pH triggers non-canonical conformational changes in the EnvZ–OmpR system.

Read more: DOI 10.1016/j.jmb.2025.169345

Congrats to Victoria!

[Anand Lab @anandlabpsu]

Huge shoutout to @ajoygramm for delivering a fantastic talk on SARS-CoV-2 dynamics at #ASMS2025! 🧬🦠🔥 So proud to see your hard work and insight shared on such a big stage. #SciComm #MassSpec #SARSCoV2

[Anand Lab @anandlabpsu]

Proud of Varun for all his work on PKA reset through fantastic integration of HDXMS, Cryo-EM, and Native MS! Come check out his poster from 10:30-2:30 at poster # 606 at #ASMS2025

[Anand Lab @anandlabpsu]

It’s always great meeting up with past students and getting to see them present! Great work @TulsianNikhil on your #ASMS2025 talk today!

[Anand Lab @anandlabpsu]

Come check out our graduate student @victori84080201’s poster here at #ASMS2025
She’ll be at poster # 401 today from 10:30-12, and 1-2:30
We’re proud of all the incredible work she does and can’t wait for her to share it with you!

[Penn State Chemistry @psu_chemistry]

A new study by the @anandlabpsu reveals mechanism responsible for resetting key molecular cycle involved in response to stress and starvation!

Read more: https://t.co/auqmd4jYh5

@PSUScience @penn_state @PSUresearch @J_A_C_S #PennStateChemistry #PKA #biochemistry

[Anand Lab @anandlabpsu]

Huge congratulations to Dr. Sean Braet for successfully defending his PhD! An incredible achievement after years of hard work, dedication, and perseverance. We’re proud to see him reach this milestone and excited for what comes next!

[Anand Lab @anandlabpsu]

Huge congratulations to Dr. Buckley for successfully defending her dissertation on Friday! She’s officially the first PhD to defend from our lab at PSU— blazing the trail with brilliance, grit, and grace. We couldn't be prouder!

[Anand Lab @anandlabpsu]

Congratulations to our amazing undergraduate student, Molly Clawson for defending her senior honors thesis on viral capsid dynamics in RNA viruses. Next stop: nursing school! We can’t wait to see what the future holds for you, Molly!

[Anand Lab @anandlabpsu]

Excited to share our lab's most recent publication! This work delves into the structure of PKA type 1 reset holoenzyme! Congratulations @VarunVenkat2559 for leading this incredible work! https://t.co/TDyue3WNfE

[Ganesh S Anand @GaneshSAnand1]

Delighted to share our group’s integrative cryo-EM and structural MS of PKA type I reset holoenzyme. This exciting work led by Varun (@VarunVenkat2559) and other Penn State colleagues caps a long search for structure of the elusive holoenzyme and highlights ensemble behavior.

[Ganesh S Anand @GaneshSAnand1]

Pleased to share our group’s review of virus breathing and dynamics!
Thank you ⁦⁦@anandlabpsu⁩ https://t.co/R3iLZG8xLw