DPd or DKd in relapsed myeloma? Efficacy may be similar—but toxicity differs.
Our real-world study of 399 patients:
• mPFS: 15 vs 12 mo (p=0.20) • Grade ≥3 neutropenia: 36% vs 23% • CV events: 18% vs 29%
Distinct toxicity profiles may guide regimen selection.
The future of multiple myeloma treatment is shaped by clinical trials but where is that research happening?
Is innovation concentrated in just a handful of countries?
Which countries are leading multiple myeloma clinical research?
Where are early and late phase trials conducted?
New Publication: Double-hit vs single-hit high-risk NDMM in transplant-eligible patients (n=154). Higher post-ASCT ORR in single-hit (97% vs 82% , p=0.006), but no difference in PFS (36 vs 31 mo) or OS (103 vs 94 mo).
Would value your thoughts.
https://t.co/vgu4PabTIx
🧵 ASH abstracts via #USMIRC group (Myeloma subdivision): 2288 The Impact of Financial Support on the Development of Clinical Research in Multiple Myeloma: An in-Depth Analysis (1980-2024)
Presents by @AnasZayad@AtrashShebli#mmsm#ASH2024#MedTwitter
https://t.co/Hzd0SGyVwH