A

Views are my own.

[Ryan Radecki, MD MS @emlitofnote]

Remember kids, "FDA approval" doesn't mean "clinically useful" – for example, AvertD, a polygenic risk score for OUD is FDA approved, but a population-based analysis showed the attributable fraction of OUD risk to the SNVs cumulative was merely 0.40%.

https://t.co/HnzWuDOnqt

[MedPage Today @medpagetoday]

"It can't predict OUD any better than a coin flip." -- @andrewkolodny, of @BrandeisU, discussing the #AvertD test which is meant to predict opioid use disorder (OUD) risk based on genetic variants.
https://t.co/smQmEri810

[Norman Ornstein @NormOrnstein]

He learned that a simple inexpensive salve could prevent the devastation. He contacted drug companies, got them to donate the medication. He went to the leadership in the countries affected to make sure that the salve would be distributed without corruption and at no charge. 3/

[John Morales @JohnMoralesTV]

“Proof is mounting that climate change is the biggest challenge of the century. Personalize it, talk about it, meet people where they are & challenge them to prioritize it. This is a time like no other to be courageous.” —guest essay in ⁦@nytopinion⁩ https://t.co/oplw5A60Zu

[Eric Columbus @EricColumbus]

Happy 70th Birthday to Ruby Bridges, who at the age of 6 desegregated the New Orleans public schools.

She’s younger than 36 senators and only 7 years older than Barack Obama.

The past isn’t past.

[Jodi Kantor @jodikantor]

Really striking view of Tim Walz from deep in the @nytimes archives https://t.co/8OqLTC77H6

[Eric Topol @EricTopol]

The ability to manipulate the gut microbiome was restricted to pre- and probiotics,FMT. Now there's successful #CRISPR base editing
https://t.co/0ayLR3YWQq
@justsaysinmice
@Nature @EligoBio @dbikard @duportet

[Brian Tierney @BTTierney85]

reading Marie Howe’s new and selected and came upon this metaphysical stunner

[The Philadelphia Inquirer @PhillyInquirer]

The epidemic of intimate partner violence is a hidden problem for college students https://t.co/TubJBVvN6V

[Sam Adams @SamuelAAdams]

what if it’s just a story about a baby with too many shoes

[The Moth @TheMoth]

This episode also features stories from @birbigs, Beth Buchler, and Paul Nurse and is hosted by The Moth's former Artistic Director, Catherine Burns. You can listen to the story behind the photo, here: https://t.co/oKJ3viDit8 🧬🎧

[ProPublica @propublica]

New: Decades ago, Kris Hansen showed 3M that its PFAS chemicals were in people's bodies. Her bosses halted her work. As the EPA now forces the removal of the chemicals from drinking water, she wrestles with the secrets that 3M kept from her and the world. https://t.co/ooMdsghoFu

[The Philadelphia Inquirer @PhillyInquirer]

Philadelphia police and city workers dismantled a homeless encampment in Kensington early Wednesday.

Officials said the encampment clearing would be led by outreach workers, but witnesses said it was police officers who escorted away advocates and people living on the streets.

[The Culturist @the_culturist_]

How is it that one person can produce all of this?

That person lived 500 years ago — so why hasn't humanity produced another talent like him in all the time since? 🧵

[VA Research @VAResearch]

The @SecVetAffairs Denis McDonough officially opens the CReATE Motion Center @VAPhiladelphia, offering hope for Veterans with osteoarthritis through advanced treatments designed to avoid joint replacements and improve quality of life.
Read more: https://t.co/n7bf4qCByh

[Jake Blumgart @jblumgart]

Really excellent use of data and graphics in this @MaxMMarin story on the tragedies of Kensington https://t.co/QIbrXcwtJ2

[VA Research @VAResearch]

#VAResearchNewsBrief: @VAPhiladelphia researchers and colleagues identified 126 genetic locations that affect a person’s susceptibility to #chronicpain, 69 of which were previously unknown.
#VAResearch #VeteransHealth https://t.co/PKTEKBoJ3M

[James Lucas @JamesLucasIT]

Thread of photos that look like paintings

1. Arnaud Montagard

[VA Research @VAResearch]

A groundbreaking @DeptVetAffairs Million Veteran Program cross-ancestry study finds genetic factors behind chronic pain intensity, offering insights into its complex nature and potential targeted treatments.
#VAResearch via @NatureMedicine
https://t.co/idJ2Ykd9Ht