Andrea Fava

Rheumatologist and physician scientist @JohnsHopkins 🇮🇹🇺🇸| Studying mechanisms of #Lupus | Immunology | Computational biology

[Andrea Fava @andreafava]

Urine biomarkers capture molecular responses in lupus nephritis, and may reshape how we assess treatment response.

In TULIP-LN, anifrolumab significantly reduced urinary biomarkers of histologic activity by Week 12, even in proteinuric nonresponders.

📄 https://t.co/CUlSNZwLOv

[Soumya Raychaudhuri সৌম্য রায়চৌধুরী @soumya_boston]

So excited to share our latest with Betty Diamond and many colleagues from the AMP RA/SLE consortium, @NIH_NIAMS , and @NIAIDNews ! A large-scale blood and tissue atlas of Lupus Nephritis! https://t.co/c1SAlMnRcu

[Andrea Fava @andreafava]

@SilvanaDebened7 Benissimo - siamo in Liguria! Tutto bene voi?

[Andrea Fava @andreafava]

Preload deficiency as a treatable cause of fatigue and exercise intolerance in SLE - The Lancet Rheumatology https://t.co/H1uOJDMMaY

[The Lancet Rheumatology @TheLancetRheum]

NEW Correspondence—Preload deficiency as a treatable cause of fatigue and exercise intolerance in #SLE https://t.co/SbRcEhSKUS

[Andrea Fava @andreafava]

@luigiadamomdphd

[Hopkins Med News @HopkinsMedNews]

Pericarditis recurrence in lupus more likely among patients receiving oral prednisone. @andreafava @GoHealio
https://t.co/2caBtOgH0b

[Luigi Adamo @luigiadamomdphd]

@YooJinKimYJK led our @hopkinsheart + @andreafava @HopkinsRheum team in investigating recurrent pericarditis in Lupus. Oral prednisone therapy increased recurrence risk. Further evidence that prednisone should be minimized in lupus?⁦@JAMANetworkOpen⁩ https://t.co/qnSKVSJXax

[Dr. John Cush @RheumNow]

268/279 SLE pts w/ kidney biopsy for proteinuria were Dx w/ lupus nephritis. Proliferative LN (III/IV+V) had higher levels of C1q, chromatin, dsDNA, ribosomal P Abs. C1q & dsDNA independently assoc w/ proliferative LN. AutoAbs decreased in proliferative LN https://t.co/tRucgJRpDN

[ACR_Journals @ACR_Journals]

Levels of anti-C1q and anti-dsDNA were independently associated with proliferative lupus nephritis

In proliferative LN, higher baseline anti-C1q levels predicted complete response better than baseline proteinuria

In A&R
https://t.co/vaA7fv9lyP

[Preprint Club - Immunology @preprintclub]

Tomorrow #preprintHub1 @nicolas_ruffin from @karolinskainst will present a #preprint by @luigiadamomdphd lab showing how B cell-mediated antigen presentation promotes adverse cardiac remodelling in chronic heart failure 🫀🩺👷‍♀️

https://t.co/gO993aiBAb

[Dr. John Cush @RheumNow]

Low urinary IL16 levels at 12 months predicts kidney survival at 3 years better than proteinuria - @Andreafava @rheumnow #RNL2024 https://t.co/4GLmJQr46C

[Andrea Fava @andreafava]

Thanks to @FNIH_Org, @NIDDKgov , @NIH_NIAMS, @LupusOrg, @LupusResearch, the Jerome L Greene Foundation, and the Plank Foundation for their support to this work and its future development!

[Andrea Fava @andreafava]

🔬 Exciting news in #Lupus! Our latest study is out. Discover how urinary biomarkers can transform lupus nephritis diagnosis & guide treatment. Plus novel insights into disease mechanism 🚀🚀. Dive into the research here https://t.co/mLVf94Fwye #Rheumatology #Nephrology

[JCI insight @JCI_insight]

Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis: https://t.co/ax77qPy0RL

@andreafava @HopkinsMedicine
#Nephrology

[JCI insight @JCI_insight]

Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis: https://t.co/ax77qPy0RL

@andreafava @HopkinsMedicine
#Nephrology

[Andrea Fava @andreafava]

Wonderful presentation by @celia_ida on a possibly novel cell type implicated in lupus nephritis #ACR23 #ACRBest

[Eric Dein @ericdeinmd]

A#2427 #ACR23 @RheumNow
PR3+ cell abundance higher in prolif LN, more than membranous. Mostly in tuberulointerstitium
Density of PR3+ higher in glomueruli of prolif LN
Correlates with activity, not chronicity
Urinary PR3 predict renal fxn loss at 3y
@jhrheumatology @andreafava

[Andrea Fava @andreafava]

@grieshaber Congratulations!!

[Alessandra Ida Celia @celia_ida]

Honoured to receive this award! Huge thanks to @LupusAcademy for the opportunity and gratitude to my mentor @andreafava for guiding me every step of the journey! 🙏🏻#grateful #AwardWinning

[Lupus Hub @lupus_hub]

CONGRESS #EULAR2023 | @andreafava presented data on urinary biomarker levels at 3 months predicting treatment response at 12 months. CD206, CD163 and IL16 better predict treatment response in proliferative LN than proteinuria.
#Lupus #lupusnephritis

[Andrea Fava @andreafava]

@danaorange Beuautiful work - congratulations!

[Johns Hopkins Rheumatology @jhrheumatology]

‼️ Application Opening ‼️
Join us as a postdoc #T32 research fellow in the Division of #Rheumatology! Learn more: https://t.co/i3NRCWSxCu