Andrea Guala

Senior researcher. Vall d’Hebron Institute of Research and Hospital.

[Andrea Guala @andreaguala6]

In the 1st longitudinal prospective study ever, wall shear stress by 4D #WhyCMR predicted co-localised progressive ascending aorta dilation rate in patients with non-dysfunctional #bicuspid aortic valve. Brief 🧵summarising the findings. From @jaccjournals https://t.co/5JbBamOEKz

[Andrea Guala @andreaguala6]

suggesting 4Dflow-derived hemodynamics may become a therapeutic target and permit the optimization of aortic interventions. Larger studies and long FU are needed!

Full-text
https://t.co/eGKSF7vuSd

Big thanks to the patients, authors, reviewers, @VHIR_ @vallhebron and funders!

[Andrea Guala @andreaguala6]

Pts with #Marfan or #Loeys-Dietz syndrome who underwent root replacement are at high risk of distal aortic events, but the mechanisms are poorly understood. In this prospective study including pre- and post-#4Dflow #WhyCMR valve-sparing root replacement partially restores.. (1/3)

[Andrea Guala @andreaguala6]

certain downstream fluid dynamics characteristics to physiological levels, with no impact on stiffness. Results also show that the changes in aortic tortuosity consequent to surgery may modulate the hemodynamics changes. It makes me think of @HEARTinMagnet et al review... (2/3)

[Andrea Guala @andreaguala6]

@BecariosFLC @chateauform @FundlaCaixa It has been a pleasure to spend few days with all these wonderful colleagues, sharing experiences and tips, and moments of relax! Thanks to the organisers and the host!

[Andrea Guala @andreaguala6]

@DataTools4Heart @amsterdamumc @athenaRICinfo @BSC_CNS @escardio @ESCardioNews @ESC_Journals @Lynkeus_Rome @PanettaLawFirm @regionstockholm @ucl Fantastic team at SRDC, a pleasure to work together!

[Andrea Guala @andreaguala6]

Link: https://t.co/DGqVhodecb

[Andrea Guala @andreaguala6]

Aortic diameter and its growth are key for the clinical management of aortic aneurysms

Guideline-recommended method is subjective, poorly reproducible, and time-consuming

We presented an innovative image analysis method substantially outperforming current standard
#whycmr

[Andrea Guala @andreaguala6]

@cristianizquie @oscarcamararey @CarlosMartnIsl1 Congratulations!!

[Andrea Guala @andreaguala6]

@JulioChirinosMd @NAASociety @thaiscoutinhoCV @GaryPie09 @ArterySociety Congratulations!!

[Andrea Guala @andreaguala6]

False lumen thrombus presence and extent in chronic aortic dissection of the descending aorta is related to local flow characteristics, particularly blood kinetic energy. This non-invasive measure may be important to personalize patient management. Read @
https://t.co/BOQ9u2pqZJ

[Hypertension @HyperAHA]

2023 Recommendations for the Validation of Non-invasive Arterial Pulse Wave Velocity Measurement Devices for Use in Hypertension and Cardiovascular Prevention and Disease @BartSpronck @bettabianchini @rosam_bruno @andreaguala6 @ccmayer1

https://t.co/dw9IiFXOhC

[Andrea Guala @andreaguala6]

@BCN_AIM @Vic_vec @apaputDelx Congratulations Victor!!

[Bart Spronck @BartSpronck]

Are you interested in joining our multidisciplinary team at Cardiovascular Research Institute Maastricht (CARIM) as a PhD candidate in vascular biomechanics? Apply below!
https://t.co/ZzMdoiqCgH

@CARIMMaastricht @MaastrichtU @ArterySociety @VascAgeNet

[Andrea Guala @andreaguala6]

A fantastic animation on the use of vascular ageing measures in clinical practice by @RIVAIllustrati1 for @VascAgeNet @COSTprogramme . Also available with Spanish subtitles! Enjoy and spread!

ENG: https://t.co/D4YldTRB8B
ENG+ESP: https://t.co/jgV7Ey1KMX

[Andrea Guala @andreaguala6]

@DataTools4Heart @EU_Commission @UniBarcelona What a pity to be able to participate only online!! ;(

[Andrea Guala @andreaguala6]

Esteemed colleagues from the @PoliTOnews and @unito are looking for a PhD candidate to work on the association between atrial fibrillation and cognitive decline via mathematical models of the cerebral
circulation.

[Víctor M. Campello @Vic_vec]

📢 We are looking for challenge organizers focusing on African data and clinical needs for the first MICCAI conference in Africa 💻

Join us for the informational meeting on Sep 20, 2pm (CEST/UTC+2).

Contact @Vic_vec. Please, RT.

@MICCAI_Society @KarimLekadir @ja_schnabel

[Andrea Guala @andreaguala6]

@David_Ouyang @kayzayai @milos_ai @yuanneal @CedarsSinaiMed @SmidtHeart @LorenzoRighett7 In you fantastic trial (congrats, impressive) the spread of Inter-observer variation in EF seems to me much lower.

[Andrea Guala @andreaguala6]

@David_Ouyang @kayzayai @milos_ai @yuanneal @CedarsSinaiMed @SmidtHeart @LorenzoRighett7 Thanks for engaging. My question was about the distribution of the difference in EF between AI and the report. You report a mean, which may inform of bias, but not on the spread (SD, IQR, 95%CI, any of them), which informs, IMO, about the reliability of the prediction.

[Andrea Guala @andreaguala6]

@David_Ouyang @kayzayai @milos_ai @yuanneal @CedarsSinaiMed @SmidtHeart @LorenzoRighett7 Other important information to understand the performance would be the number of patients with the diseases to be predicted in the testing set. How many pts had prior mitraclip, TAVR, pacemaker, or had heart failure, dilated LV and LA? What were the sens., spec., NPV and PPV?

[Andrea Guala @andreaguala6]

@David_Ouyang @kayzayai @milos_ai @yuanneal @CedarsSinaiMed @SmidtHeart @LorenzoRighett7 Congratulations! Just a question, what is the spread of the predictions of EF? From the figure it seems substantial and likely large then inter-observer reproducibility or scan-rescan variation, but the report only includes mean error and mean error with bootstrapping.