Andy Fraser

you can't put a fire out with gasoline.

apparently i need to say that my opinions are my opinions. so there you go.

[バイオステーション(Bio-station)/ポッドキャスト @Bio_stations]

シーケンスによる代謝物の定量法(smol-seq)

標的代謝物が結合したときに構造が変化することでバーコードDNAを遊離するアプタマーをデザイン。バーコードをシーケンスすることで代謝物量を測定。高い特異性と多重検出能力を持ち、診断や治療応用にも期待ー面白いアイデアです
https://t.co/nWuPHSjnZ5

[Andy Fraser @andy_utoronto]

paper is at:
https://t.co/9L7UtX7Tgo or
https://t.co/jxKnt9MhMX
or
https://t.co/XNNwl3QqIE (open access)

[Andy Fraser @andy_utoronto]

Delighted to share our paper describing a way to read levels of 100s of metabolites or drugs in parallel using DNA sequencing. This method which we call ‘smol-seq’ (Small MOLecule sequencing) harnesses the power of DNA sequencing for metabolite detection
https://t.co/jxKnt9MhMX

[Andy Fraser @andy_utoronto]

Finally - we are now hiring multiple positions to bring this tech to reality. If you have aptamer experience or are a compbio person excited to learn how to predict aptamer-target interactions, please DM me!

[Andy Fraser @andy_utoronto]

@laurpelletier Thx Laurence!

[Andy Fraser @andy_utoronto]

@mike_tilapia thx Mikko!

[Andy Fraser @andy_utoronto]

@drugmonkeyblog Glad to see an honest direct post instead of toxic positivity “don’t give up!” crap. I can’t think of anything that isn’t fucked by this and the more I try the worse it gets. This empowers every horrible nasty violent corrupt bigoted ignorant person and regime.

[Roddy 🇨🇦 @RodKahx]

This needs to be unequivocally disqualifying as a Prime Minister of Canada.

Full stop.

[Beth Levy @Beth_Levy66]

Do you have one of those fancy interactive maps for

Where to find a family doctor
Open ER
Deeply affordable housing unit
Properly funded school
A moment in time where your government wasn’t wasting money on Beer

#ONpoli

[Gil Meslin @g_meslin]

Paying $13M for the repairs necessary to keep the Ontario Science Centre open through to 2034 would have been the equivalent of reducing the $200 pre-election handout cheques to $199.19.

[Norm Di Pasquale 🇨🇦 @normsworld]

And you wonder why we want safe, separated bike lanes on Yonge? #bikeTO #topoli #onpoli

[Alex Bozikovic @alexbozikovic]

This is aggressively stupid. It will accomplish nothing but to get people killed.

[André Picard @picardonhealth]

Canada’s Geoffrey Hinton, #AI pioneer, and @UofT computer science professor, co-winner of #NobelPrize in Physics with American John Hopfield, by ⁦@IvanSemeniuk⁩ via ⁦@globeandmail⁩ ⁦@NobelPrize⁩ https://t.co/WsXU8sre8v

[Andy Fraser @andy_utoronto]

@picardonhealth @alexbozikovic @globeandmail “Will nobody think of the parking revenues??!”(aaarghh)