Centre sets up a 3-member panel, chaired by NITI Aayog member Dr M Srinivas, with former Union health secretary Preeti Sudan and Medanta chairman Dr Naresh Trehan, after the Supreme Court flagged the failure of existing rules to curb unethical pharma marketing, including inducements to doctors and promotion of irrational, high-priced drugs.
#SupremeCourt
#Pharma #Healthcare #MedicalEthics @timesofindia@amitanandTOI@MoHFW_INDIA
@airindia Hi all terms and conditions met , inventary is available , i got the mail
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An Anti-Aging Vitamin? Yes.
A vitamin that slowed biological aging in a randomized controlled trial (but only for these people).
https://t.co/bZ8yuSvbaO
The Lu et al. paper shows OSK boosts GSTA4 to clear toxic 4-HNE from lipid peroxidation, restoring oxidative resilience and rejuvenating aged RPE without full reprogramming. GSTA4 rises in many longevity interventions.
This pathway links to fertility because ovarian aging and oocyte quality decline heavily involve oxidative stress and 4-HNE buildup, which damages mitochondria, spindles, and DNA. GSTA4 is expressed in ovaries; partial OSK/OSKM reprogramming (e.g., hypothalamic) has already extended fertility and raised pregnancy rates in aged rats.
For skin aging, UV and ROS drive 4-HNE accumulation; GSTA4 is highly expressed in keratinocytes and induced by stress. Partial OSK reprogramming rejuvenates skin epigenetically, thickens epidermis, cuts senescence, and speeds healing—likely aided by the same resilience axis.
@Y_Ryan_Lu@ImmunoFever Hi i am
Working in fertility , recent nature shows 4-HNE accumulation causes ovarian ageing & Glutathione is the break . Really wish to know ur thoughts and how u can help us
Age related bone deterioration may be partially reversible by restoring mitochondrial communication between cells, rather than replacing damaged ones.
More important, it raises the possibility that mitochondrial dysfunction within the bone marrow environment drives the aging of stem cells.
https://t.co/knOrmCn2hJ