Interesting: @anna_masato & Luigi Bubacco review the important detail of the half-life of the #Parkinsons-associated protein alpha synuclein, which appears to "strongly depends on the cellular models & the experimental strategy used in each specific study"
https://t.co/e72m8tVGP3
⭐Introducing our new Biomedical Sciences lecturer - Susanna Cogo
Susanna was previously a postdoctoral researcher at @UniofReading conducting research into parkinsons and specialises in neuroscience and cell biology.
Look out for her in your upcoming practicals and lectures!🥼
Ever wondered how great discoveries are made? Have a look at this journal club, where I describe how a bit of stubbornness (and luck!) led Arvid Carlsson to the breakthrough discovery of the role of dopamine in brain physiology 🧠@NatRevNeurosci
https://t.co/NpQQBlRmLc
To the axon, RNA regulation, neurotrophin, and cytoskeleton nerds and nerdettes out there:
Ta-dah!! :)
(Summary thread coming soon).
BDNF controls phosphorylation and transcriptional networks governing cytoskeleton organization and axonal regeneration https://t.co/xz8mHtCS0k
Happy to share our latest article on aSynuclein and DOPAL role in Parkinson's disease neurodegeneration! Thank you @luigibubacco, Daniela Boassa, @NPlotegher and all our co-authors for their contribution!! https://t.co/AcPt9GXCNr
New @biorxivpreprint manuscript from @anna_masato@luigibubacco & colleagues presents data that dopamine metabolite DOPAL initiates α synuclein-mediated impaired proteostasis in neuronal projections that may lead to enhanced vulnerability in #Parkinsons
https://t.co/2kkEvUTiyC